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Pyrazinamide is a medication used to treat tuberculosis. For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol. It is not generally recommended for the treatment of latent tuberculosis. It is taken by mouth.
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tuberculosis used acid treatment pyrazinoic citation needed resistance pnca liver side effects rifampicin isoniazid rpsa mutations use pyrazinamidase activity also
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Pyrazinamide | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Pyrazinamide | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Pyrazinamide | ATC code | J04AK01 (WHO) J04AM09 (WHO), J04AM10 (WHO), J04AM11 (WHO), J04AM12 (WHO) | 1.00 | infobox |
| Pyrazinamide | Bioavailability | >90% | 1.00 | infobox |
| Pyrazinamide | CAS Number | 98-96-4 Y | 1.00 | infobox |
| Pyrazinamide | ChEBI | CHEBI:45285 Y | 1.00 | infobox |
| Pyrazinamide | ChEMBL | ChEMBL614 Y | 1.00 | infobox |
| Pyrazinamide | ChemSpider | 1017 Y | 1.00 | infobox |
| Pyrazinamide | CompTox Dashboard (EPA) | DTXSID9021215 | 1.00 | infobox |
| Pyrazinamide | DrugBank | DB00339 Y | 1.00 | infobox |
| Pyrazinamide | ECHA InfoCard | 100.002.470 | 1.00 | infobox |
| Pyrazinamide | Elimination half-life | 9 to 10 hours | 1.00 | infobox |
| Pyrazinamide | Excretion | Kidney | 1.00 | infobox |
| Pyrazinamide | Formula | C5H5N3O | 1.00 | infobox |
| Pyrazinamide | IUPHAR/BPS | 7287 | 1.00 | infobox |
| Pyrazinamide | KEGG | D00144 Y | 1.00 | infobox |
| Pyrazinamide | Legal status | US: ℞-only | 1.00 | infobox |
| Pyrazinamide | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Pyrazinamide | License data | US DailyMed: Pyrazinamide | 1.00 | infobox |
| Pyrazinamide | MedlinePlus | a682402 | 1.00 | infobox |
| Pyrazinamide | Metabolism | Liver | 1.00 | infobox |
| Pyrazinamide | Molar mass | 123.115 g·mol−1 | 1.00 | infobox |
| Pyrazinamide | NIAID ChemDB | 007697 | 1.00 | infobox |
| Pyrazinamide | PubChem CID | 1046 | 1.00 | infobox |
| Pyrazinamide | Routes of administration | By mouth | 1.00 | infobox |
| Pyrazinamide | Trade names | Rifater, Tebrazid, others | 1.00 | infobox |
| Pyrazinamide | UNII | 2KNI5N06TI | 1.00 | infobox |
| Pyrazinamide | is a | medication used to treat tuberculosis | 0.90 | text |
| Pyrazinamide | is a | potent antiuricosuric drug and consequently has an off-label use in the diagnosis of causes of hypouricemia and hyperuricosuria | 0.90 | text |
| Pyrazinamide | is a | most common cause of drug-induced hepatitis | 0.90 | text |
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