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Ethambutol

Ethambutol (EMB, E) is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii. It is taken by mouth.

Standards, Overview & Mechanism of action

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Explore the main themes, entities and connections around Ethambutol. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J04AK02 (WHO) J04AM09 (WHO)
CAS Number
74-55-5 Y
ChEBI
CHEBI:4877
ChEMBL
ChEMBL44884

Topics to explore

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Overview

Chirality and biological activity

Adverse effects

Mechanism of action

Pharmacokinetics

Advanced semantic analysis

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Map overview Semantic statistics

Ethambutol

Nodes41
Edges40
Triples40
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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Ethambutol

Top relations

related to Chirality and biological activity · 6
Ethambutol → Hence, It, On, The, This, Toxicity
related to Mechanism of action · 5
Ethambutol → D-arabinose, Disruption, It, Mycolic, TB
has effect · 4
Ethambutol → ArthralgiaHyperuricaemiaVertical, Optic, People, Red
Legal status · 2
Ethambutol → AU: S4 (Prescription only), In general: ℞ (Prescription only)
3D model (JSmol) · 1
Ethambutol → Interactive image
AHFS/Drugs.com · 1
Ethambutol → Monograph
ATC code · 1
Ethambutol → J04AK02 (WHO) J04AM09 (WHO)
CAS Number · 1
Ethambutol → 74-55-5 Y
ChEBI · 1
Ethambutol → CHEBI:4877
ChEMBL · 1
Ethambutol → ChEMBL44884

Important terminology Word statistics

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Important terminology

used problems tuberculosis effects complex treat pregnancy optic neuritis use medication side include arabinogalactan metabolism mouth liver -ethambutol drug cell

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ethambutol3D model (JSmol)Interactive image1.00infobox
EthambutolAHFS/Drugs.comMonograph1.00infobox
EthambutolATC codeJ04AK02 (WHO) J04AM09 (WHO)1.00infobox
EthambutolCAS Number74-55-5 Y1.00infobox
EthambutolChEBICHEBI:48771.00infobox
EthambutolChEMBLChEMBL448841.00infobox
EthambutolChemSpider134331.00infobox
EthambutolCompTox Dashboard (EPA)DTXSID80230061.00infobox
EthambutolDrugBankDB003301.00infobox
EthambutolECHA InfoCard100.000.7371.00infobox
EthambutolElimination half-life3–4 hours1.00infobox
EthambutolFormulaC10H24N2O21.00infobox
EthambutolKEGGD079251.00infobox
EthambutolLegal statusAU: S4 (Prescription only)1.00infobox
EthambutolLegal statusIn general: ℞ (Prescription only)1.00infobox
EthambutolLicense dataUS DailyMed: Ethambutol1.00infobox
EthambutolMetabolismliver1.00infobox
EthambutolMolar mass204.314 g·mol−11.00infobox
EthambutolOther names(2S,2’S)-2,2’-(Ethane-1,2-diyldiimino)dibutan-1-ol1.00infobox
EthambutolProtein binding20–30%1.00infobox
EthambutolPubChem CID140521.00infobox
EthambutolRoutes of administrationBy mouth1.00infobox
EthambutolTrade namesMyambutol, Etibi, Servambutol, others1.00infobox
EthambutolUNII8G167061QZ1.00infobox

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