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Prothrombin complex concentrate

Prothrombin complex concentrate (PCC), also known as factor IX complex, sold under the brand name Kcentra among others, is a combination medication made up of blood clotting factors II, IX, and X(3-factor PCC) or, when also containing factor VII as does Kcentra, 4-factor PCC. It is used to treat and prevent bleeding in hemophilia B if pure factor IX is…

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AHFS/Drugs.com
Monograph Monograph
ATC code
B02BD01 (WHO) B02BD04 (WHO)
CAS Number
37224-63-8 Y
DrugBank
DB11330 · DB13152
Factor II
Blood clotting factor
Factor IX
Blood clotting factor

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Overview

Medical uses

Contraindications

Chemistry

History

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Prothrombin complex concentrate

Nodes36
Edges35
Triples47
Avg. degree1.94
Density0.055556
Components1

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Prothrombin complex concentrate

Top relations

related to Medical uses · 9
Prothrombin complex concentrate → American College, Chest Physicians, For, INR, It, No, Other, Prothrombin, Several
related to Economics · 8
Prothrombin complex concentrate → AUD, Authority, In, IU, Prothrombinex, The Australian National Blood, United States, US
related to Chemistry · 7
Prothrombin complex concentrate → Heparin, II, IX, Prothrombin, Some, Typically, VII
Legal status · 5
Prothrombin complex concentrate → CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Contraindications · 4
Prothrombin complex concentrate → As PCC, However, PCC, The
DrugBank · 2
Prothrombin complex concentrate → DB11330, DB13152
AHFS/Drugs.com · 1
Prothrombin complex concentrate → Monograph Monograph
ATC code · 1
Prothrombin complex concentrate → B02BD01 (WHO) B02BD04 (WHO)
CAS Number · 1
Prothrombin complex concentrate → 37224-63-8 Y
Factor II · 1
Prothrombin complex concentrate → Blood clotting factor

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Important terminology

prothrombin complex concentrate factor ix may also used blood clotting factors hemophilia bleeding available effects include warfarin ii vii pcc

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Prothrombin complex concentrateAHFS/Drugs.comMonograph Monograph1.00infobox
Prothrombin complex concentrateATC codeB02BD01 (WHO) B02BD04 (WHO)1.00infobox
Prothrombin complex concentrateCAS Number37224-63-8 Y1.00infobox
Prothrombin complex concentrateDrugBankDB113301.00infobox
Prothrombin complex concentrateDrugBankDB131521.00infobox
Prothrombin complex concentrateFactor IIBlood clotting factor1.00infobox
Prothrombin complex concentrateFactor IXBlood clotting factor1.00infobox
Prothrombin complex concentrateFactor VIIBlood clotting factor1.00infobox
Prothrombin complex concentrateFactor XBlood clotting factor1.00infobox
Prothrombin complex concentrateLegal statusCA: ℞-only1.00infobox
Prothrombin complex concentrateLegal statusUK: POM (Prescription only)1.00infobox
Prothrombin complex concentrateLegal statusUS: ℞-only1.00infobox
Prothrombin complex concentrateLegal statusEU: Rx-only1.00infobox
Prothrombin complex concentrateLegal statusIn general: ℞ (Prescription only)1.00infobox
Prothrombin complex concentrateLicense dataUS DailyMed: Kcentra1.00infobox
Prothrombin complex concentrateOther namesfactor IX complex1.00infobox
Prothrombin complex concentrateRoutes of administrationIntravenous1.00infobox
Prothrombin complex concentrateTrade namesKcentra, others1.00infobox
Prothrombin complex concentrateUNIIRZ22DI43TP1.00infobox

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