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Leronlimab

Leronlimab (codenamed PRO 140) is a humanized monoclonal antibody targeted against the CCR5 receptor found on T lymphocytes of the human immune system. It is being investigated as a potential therapy in the treatment of triple negative breast cancer and HIV infection.

Development, Mechanism of action & Overview

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Key facts & relationships

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ATC code
none
CAS Number
674782-26-4 Y
ChEMBL
ChEMBL2109343
ChemSpider
none
DrugBank
DB05941 Y
KEGG
D11399

Topics to explore

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Overview

Development

Mechanism of action

Advanced semantic analysis

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Map overview Semantic statistics

Leronlimab

Nodes34
Edges33
Triples51
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

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Leronlimab

Top relations

related to Development · 26
Leronlimab → ART, ASM Microbe, August, BLA, CytoDyn, Cytodyn Inc, FDA, HAART, HIV, HIV RNA, HIV-1 RNA, HIV-infected, If, In, In December, In February, In March, In May, January, On
related to External links · 7
Leronlimab → Action, Animation, COM, HER2, January, Leronlimab Mechanism, Retrieved
related to COVID-19 · 6
Leronlimab → CD10, CD12, COVID-19, CytoDyn, Inc, With
ATC code · 1
Leronlimab → none
CAS Number · 1
Leronlimab → 674782-26-4 Y
ChEMBL · 1
Leronlimab → ChEMBL2109343
ChemSpider · 1
Leronlimab → none
DrugBank · 1
Leronlimab → DB05941 Y
KEGG · 1
Leronlimab → D11399
NIAID ChemDB · 1
Leronlimab → 088103

Important terminology Word statistics

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Important terminology

pro 140 cytodyn patients ccr5 hiv antibody trial treatment breast 2019 cancer drug covid-19 viral monoclonal also humanized fda mtnbc

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LeronlimabATC codenone1.00infobox
LeronlimabCAS Number674782-26-4 Y1.00infobox
LeronlimabChEMBLChEMBL21093431.00infobox
LeronlimabChemSpidernone1.00infobox
LeronlimabDrugBankDB05941 Y1.00infobox
LeronlimabKEGGD113991.00infobox
LeronlimabNIAID ChemDB0881031.00infobox
LeronlimabOther namesPRO 1401.00infobox
LeronlimabSourceHumanized1.00infobox
LeronlimabTargetCCR51.00infobox
LeronlimabTypeWhole antibody1.00infobox
LeronlimabUNIIY1J4NP8FF01.00infobox

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