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Conjugated estrogens

Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. It is a mixture of the sodium salts of estrogen conjugates found in horses, such as estrone sulfate and equilin sulfate. CEEs are…

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17α-Dihydro-equilin sulfate
Estrogen
AHFS/Drugs.com
Multum Consumer Information
ATC code
G03CA57 (WHO)
Bioavailability
Variable
CAS Number
12126-59-9 Y
ChEBI
CHEBI:8389

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Conjugated estrogens

Nodes176
Edges175
Triples84
Avg. degree1.99
Density0.011364
Components1

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Conjugated estrogens

Top relations

related to Names · 28
Conjugated estrogens → Australia, Canada, CEEs, Cenestin, Congest, English-speaking, Enjuvia, Estrogens, Ireland, It, JANTooltip Japanese Accepted Name, Major, Many, New Zealand, Premarin, Premelle, Premia, Premique, Prempak, Prempak-C
related to history · 20
Conjugated estrogens → Abbreviated New Drug Application, ANDA, Biochemistry, Both, Conjugated, Department, Emmenin, Estrone, FDA, Federal Register, In, Kefauver Harris Amendment, NIH, Premarin, Progynon, The, This, Toronto, University, Wyeth Ayerst
Legal status · 3
Conjugated estrogens → CA: ℞-only, In general: ℞ (Prescription only), US: ℞-only
17α-Dihydro-equilin sulfate · 1
Conjugated estrogens → Estrogen
AHFS/Drugs.com · 1
Conjugated estrogens → Multum Consumer Information
ATC code · 1
Conjugated estrogens → G03CA57 (WHO)
Bioavailability · 1
Conjugated estrogens → Variable
CAS Number · 1
Conjugated estrogens → 12126-59-9 Y
ChEBI · 1
Conjugated estrogens → CHEBI:8389
ChEMBL · 1
Conjugated estrogens → ChEMBL1201649

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Important terminology

cees estrogens estradiol estrogen estrone oral equilin premarin sulfate used breast effects mg women cancer risk brand united urine found

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Conjugated estrogens17α-Dihydro-equilin sulfateEstrogen1.00infobox
Conjugated estrogensAHFS/Drugs.comMultum Consumer Information1.00infobox
Conjugated estrogensATC codeG03CA57 (WHO)1.00infobox
Conjugated estrogensBioavailabilityVariable1.00infobox
Conjugated estrogensCAS Number12126-59-9 Y1.00infobox
Conjugated estrogensChEBICHEBI:83891.00infobox
Conjugated estrogensChEMBLChEMBL12016491.00infobox
Conjugated estrogensChemSpider570974 Y1.00infobox
Conjugated estrogensCompTox Dashboard (EPA)DTXSID90211861.00infobox
Conjugated estrogensDrug classEstrogen1.00infobox
Conjugated estrogensDrugBankDB002861.00infobox
Conjugated estrogensECHA InfoCard100.031.9871.00infobox
Conjugated estrogensElimination half-lifeEstrone: 26.7 hours Estrone (BA): 14.8 hours Equilin: 11.4 hours[unreliable medical source?]1.00infobox
Conjugated estrogensEquilin sulfateEstrogen1.00infobox
Conjugated estrogensEstrone sulfateEstrogen1.00infobox
Conjugated estrogensExcretionKidney1.00infobox
Conjugated estrogensKEGGD040701.00infobox
Conjugated estrogensLegal statusCA: ℞-only1.00infobox
Conjugated estrogensLegal statusUS: ℞-only1.00infobox
Conjugated estrogensLegal statusIn general: ℞ (Prescription only)1.00infobox
Conjugated estrogensMetabolismLiver1.00infobox
Conjugated estrogensOther namesCEs; Conjugated equine estrogens; CEEs; Pregnant mares' urine; Estrogens, conjugated1.00infobox
Conjugated estrogensProtein bindingHigh (to albumin and SHBGTooltip sex hormone-binding globulin)1.00infobox
Conjugated estrogensPubChem CID6566131.00infobox
Conjugated estrogensRoutes of administrationBy mouth, topical, vaginal, intravenous injection, intramuscular injection1.00infobox
Conjugated estrogensTrade namesCenestin, Enjuvia, Premarin, others1.00infobox
Conjugated estrogensUNIIIU5QR144QX1.00infobox

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