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Medrogestone

Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. It is taken by mouth.

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3D model (JSmol)
Interactive image
ATC code
G03DB03 (WHO) G03FB07 (WHO) (with estrogen)
Bioavailability
Nearly 100%
CAS Number
977-79-7
ChemSpider
8125459
CompTox Dashboard (EPA)
DTXSID70878637

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Overview

Medical uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

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Map overview Semantic statistics

Medrogestone

Nodes130
Edges129
Triples90
Avg. degree1.98
Density0.015385
Components1

How this topic connects Entity context

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Medrogestone

Top relations

related to Availability · 10
Medrogestone → Argentina, Canada, Egypt, Europe, France, Germany, Hong Kong, However, Tunisia, United States
related to Generic names · 8
Medrogestone → AY-62022, BANTooltip British Approved Name, INNTooltip International Nonproprietary Name, It, Name, NSC-123018, R-13615, USANTooltip United States Adopted
related to Brand names · 7
Medrogestone → Ayerluton, Colpro, Colpron, Colprone, Etogyn, Presomen, Prothil
related to Chemistry · 7
Medrogestone → C17α, C6, C7, In, It, The, This
related to Pharmacodynamics · 7
Medrogestone → Accordingly, Although, Clauberg, HDL, However, In, There
related to Pharmacokinetics · 4
Medrogestone → After, Cmax, The, Upon
related to history · 3
Medrogestone → French, In, The BMJ
related to Medical uses · 3
Medrogestone → Cyclic, In, It
related to Synthesis · 3
Medrogestone → Incorporation, The, This
3D model (JSmol) · 1
Medrogestone → Interactive image

Important terminology Word statistics

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Important terminology

activity progesterone progestin progestogen effects available drug glucocorticoid names found acetate treatment progestogens weak described synthetic antimineralocorticoid side brand name

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Medrogestone3D model (JSmol)Interactive image1.00infobox
MedrogestoneATC codeG03DB03 (WHO) G03FB07 (WHO) (with estrogen)1.00infobox
MedrogestoneBioavailabilityNearly 100%1.00infobox
MedrogestoneCAS Number977-79-71.00infobox
MedrogestoneChemSpider81254591.00infobox
MedrogestoneCompTox Dashboard (EPA)DTXSID708786371.00infobox
MedrogestoneDrug classProgestogen; Progestin1.00infobox
MedrogestoneDrugBankDB091241.00infobox
MedrogestoneECHA InfoCard100.012.3231.00infobox
MedrogestoneElimination half-life35–36 hours1.00infobox
MedrogestoneFormulaC23H32O21.00infobox
MedrogestoneKEGGD048851.00infobox
MedrogestoneLegal statusIn general: ℞ (Prescription only)1.00infobox
MedrogestoneMetabolismHepatic (hydroxylation)1.00infobox
MedrogestoneMolar mass340.507 g·mol−11.00infobox
MedrogestoneOther namesMetrogestone; Medrogesterone; AY-62022, NSC-123018, R-13615; 6,17α-Dimethyl-6-dehydroprogesterone; 6,17α-Dimethyl-4,6-pregnadiene-3,20-dione1.00infobox
MedrogestonePregnancy categoryX1.00infobox
MedrogestoneProtein binding95%: Albumin (90%), CBGTooltip corticosteroid-binding globulin (3%), SHBGTooltip sex hormone-binding globulin (2%)1.00infobox
MedrogestonePubChem CID99498481.00infobox
MedrogestoneRoutes of administrationBy mouth1.00infobox
MedrogestoneTrade namesColprone, others1.00infobox
MedrogestoneUNII077DN93G5B1.00infobox
Medrogestoneis aprogestin0.90text

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