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PRDX4: Interactions & Overview

Peroxiredoxin-4 is a protein that in humans is encoded by the PRDX4 gene. It is a member of the peroxiredoxin family of antioxidant enzymes.

Language: English [EN]
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PRDX4 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around PRDX4.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
97
Concept neighborhoods
7
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 3 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.11.1.24
Aliases
PRDX4, AOE37-2, AOE372, HEL-S-97n, PRX-4, peroxiredoxin 4
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PN8, 3TJB, 3TJF, 3TJG, 3TJJ, 3TJK, 3TKP, 3TKQ, 3TKR, 3TKS, 4RQX
Band
Xp22.11 · X F3|X 72.38 cM
Bgee
body of pancreas · tibia · islet of Langerhans · parotid gland · stromal cell of endometrium
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PRDX4 connects Entity context

The extracted context around PRDX4 shows recurring relationship patterns in the source. For example, PRDX4 → 4-hydroxyproline metabolic process, antioxidant activity, cell redox homeostasis, cellular oxidant detoxification, cytoplasm, cytosol, endoplasmic reticulum, extracellular exosome, extracellular matrix organization, extracellular region, extracellular space, ficolin-1-rich granule lumen, hydrogen peroxide catabolic process, I-kappaB phosphorylation, male gonad development, mitochondrion, negative regulation of male germ cell proliferation, neutrophil degranulation, nucleus, oxidoreductase activity Another extracted example is PRDX4 → beta cell, body of pancreas, cartilage tissue, cumulus cell, dermis, endocardial cushion, external carotid artery, gonad, Gonadal ridge, islet of Langerhans, left testis, maxillary prominence, otic placode, otic vesicle, parotid gland, right testis, saccule, stromal cell of endometrium, tibia, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

PRDX4

Top relations

Gene ontology · 31
PRDX4 → 4-hydroxyproline metabolic process, antioxidant activity, cell redox homeostasis, cellular oxidant detoxification, cytoplasm, cytosol, endoplasmic reticulum, extracellular exosome, extracellular matrix organization, extracellular region, extracellular space, ficolin-1-rich granule lumen, hydrogen peroxide catabolic process, I-kappaB phosphorylation, male gonad development, mitochondrion, negative regulation of male germ cell proliferation, neutrophil degranulation, nucleus, oxidoreductase activity
Bgee · 20
PRDX4 → beta cell, body of pancreas, cartilage tissue, cumulus cell, dermis, endocardial cushion, external carotid artery, gonad, Gonadal ridge, islet of Langerhans, left testis, maxillary prominence, otic placode, otic vesicle, parotid gland, right testis, saccule, stromal cell of endometrium, tibia, vas deferens
RNA expression pattern · 20
PRDX4 → beta cell, body of pancreas, cartilage tissue, cumulus cell, dermis, endocardial cushion, external carotid artery, gonad, Gonadal ridge, islet of Langerhans, left testis, maxillary prominence, otic placode, otic vesicle, parotid gland, right testis, saccule, stromal cell of endometrium, tibia, vas deferens
Band · 2
PRDX4 → X F3|X 72.38 cM, Xp22.11
Chr. · 2
PRDX4 → X chromosome (human), X chromosome (mouse)
End · 2
PRDX4 → 154,123,750 bp, 23,686,397 bp
1.11.1.24 · 1
PRDX4 → ↗
Aliases · 1
PRDX4 → PRDX4, AOE37-2, AOE372, HEL-S-97n, PRX-4, peroxiredoxin 4
Available structures · 1
PRDX4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PN8, 3TJB, 3TJF, 3TJG, 3TJJ, 3TJK, 3TKP, 3TKQ, 3TKR, 3TKS, 4RQX
BioGPS · 1
PRDX4 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp peroxiredoxin gene chr human band protein chromosome antioxidant 11 location family mouse function encoded external search activity 686 397

PRDX4 relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around PRDX4. Examples in this analysis include PRDX4 → 1.11.1.24 → ↗ and PRDX4 → Aliases → PRDX4, AOE37-2, AOE372, HEL-S-97n, PRX-4, peroxiredoxin 4. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PRDX41.11.1.241.00infobox
PRDX4AliasesPRDX4, AOE37-2, AOE372, HEL-S-97n, PRX-4, peroxiredoxin 41.00infobox
PRDX4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PN8, 3TJB, 3TJF, 3TJG, 3TJJ, 3TJK, 3TKP, 3TKQ, 3TKR, 3TKS, 4RQX1.00infobox
PRDX4BandXp22.111.00infobox
PRDX4BandX F3|X 72.38 cM1.00infobox
PRDX4Bgeebody of pancreas1.00infobox
PRDX4Bgeetibia1.00infobox
PRDX4Bgeeislet of Langerhans1.00infobox
PRDX4Bgeeparotid gland1.00infobox
PRDX4Bgeestromal cell of endometrium1.00infobox
PRDX4Bgeebeta cell1.00infobox
PRDX4Bgeegonad1.00infobox
PRDX4Bgeeright testis1.00infobox
PRDX4Bgeeleft testis1.00infobox
PRDX4Bgeecartilage tissue1.00infobox
PRDX4Bgeesaccule1.00infobox
PRDX4Bgeeotic placode1.00infobox
PRDX4Bgeeotic vesicle1.00infobox
PRDX4Bgeeexternal carotid artery1.00infobox
PRDX4Bgeedermis1.00infobox
PRDX4Bgeeendocardial cushion1.00infobox
PRDX4Bgeemaxillary prominence1.00infobox
PRDX4BgeeGonadal ridge1.00infobox
PRDX4Bgeevas deferens1.00infobox
PRDX4Bgeecumulus cell1.00infobox
PRDX4BioGPSMore reference expression data1.00infobox
PRDX4Chr.X chromosome (human)1.00infobox
PRDX4Chr.X chromosome (mouse)1.00infobox
PRDX4DatabasesNCBI: entry; OMA: entry1.00infobox
PRDX4End23,686,397 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PRDX4 bring nearby vocabulary together. In this analysis, examples include Activity, Enzyme and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PRDX4
    • Activity
    • Enzyme
    • External
    • Function
    • Peroxiredoxin
    • Search
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
  • prdx4
    • Activity
    • Enzyme
    • External
    • Function
    • Peroxiredoxin
    • Search
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Human
    • Prdx4
    • Activity
    • Bp
    • Chr
    • End
    • Enzyme
    • External
    • F3
    • Function
  • peroxiredoxin
    • Prdx4
    • Hydrogen
    • Peroxide
    • Search
    • Location
    • Reading
    • References
    • Cytoplasm
    • End
    • F3
    • Mouse
    • Band
  • peroxiredoxin 1
    • Prdx4
    • Hydrogen
    • Peroxide
    • Search
    • Location
    • Reading
    • References
    • Cytoplasm
    • End
    • F3
    • Mouse
    • Band
  • interactions
    • Reading
    • References
    • Search
    • Location
    • Human
    • Prdx4
    • Peroxiredoxin
  • protein
    • Search

Connections between topic areas Semantic bridges

For PRDX4, one of the stronger structural bridges in this analysis connects PRDX4 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PRDX4Overview · splits 4 ⟂ 4
PRDX4Interactions · splits 5 ⟂ 3

Map overview Semantic statistics

PRDX4

Nodes8
Edges7
Triples97
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around PRDX4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PRDX4 · EN edition · Analysis: TopicsToTalkAbout

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