Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Peroxiredoxin 1: Clinical significance, Interactions & Function

Peroxiredoxin-1 is a protein that in humans is encoded by the PRDX1 gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Peroxiredoxin 1 topic overview

The analysis highlights Clinical significance, Interactions and Function as prominent areas in the source structure around Peroxiredoxin 1.

Related topics
10
Source areas
4
Connected nodes
14
Extracted relationships
104
Related term clusters
7
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 4 topics
Interactions · 3 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.11.1.24
↗
Aliases
PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RII, 3HY2, 4XCS
Band
1p34.1 · 4 D1|4 53.28 cM
Bgee
right lobe of thyroid gland · left lobe of thyroid gland · nasal epithelium · olfactory zone of nasal mucosa · palpebral conjunctiva
BioGPS
More reference expression data

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Clinical significance

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Peroxiredoxin 1 connects Entity context

The extracted context around Peroxiredoxin 1 shows recurring relationship patterns in the source. For example, Peroxiredoxin 1 → antioxidant activity, cadherin binding, cell population proliferation, cell redox homeostasis, cellular response to oxidative stress, cytoplasm, cytosol, erythrocyte homeostasis, extracellular exosome, extracellular matrix, extracellular space, hydrogen peroxide catabolic process, identical protein binding, leukocyte activation, melanosome, mitochondrion, myelin sheath, natural killer cell activation, natural killer cell mediated cytotoxicity, nucleus Another extracted example is Peroxiredoxin 1 → C1 segment, efferent ductule, endothelial cell of lymphatic vessel, epiblast, ganglionic eminence, gingival epithelium, Gonadal ridge, gums, iris, left lobe of thyroid gland, lobe of prostate, mucosa of esophagus, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, primitive streak, right kidney, right lobe of thyroid gland, stroma of bone marrow, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

Peroxiredoxin 1

Top relations

Gene ontology · 33
Peroxiredoxin 1 → antioxidant activity, cadherin binding, cell population proliferation, cell redox homeostasis, cellular response to oxidative stress, cytoplasm, cytosol, erythrocyte homeostasis, extracellular exosome, extracellular matrix, extracellular space, hydrogen peroxide catabolic process, identical protein binding, leukocyte activation, melanosome, mitochondrion, myelin sheath, natural killer cell activation, natural killer cell mediated cytotoxicity, nucleus
Bgee · 20
Peroxiredoxin 1 → C1 segment, efferent ductule, endothelial cell of lymphatic vessel, epiblast, ganglionic eminence, gingival epithelium, Gonadal ridge, gums, iris, left lobe of thyroid gland, lobe of prostate, mucosa of esophagus, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, primitive streak, right kidney, right lobe of thyroid gland, stroma of bone marrow, vas deferens
RNA expression pattern · 20
Peroxiredoxin 1 → C1 segment, efferent ductule, endothelial cell of lymphatic vessel, epiblast, ganglionic eminence, gingival epithelium, Gonadal ridge, gums, iris, left lobe of thyroid gland, lobe of prostate, mucosa of esophagus, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, primitive streak, right kidney, right lobe of thyroid gland, stroma of bone marrow, vas deferens
related to Clinical significance · 3
Peroxiredoxin 1 → LPS, Peroxiredoxin, TNF-alpha
Band · 2
Peroxiredoxin 1 → 1p34.1, 4 D1|4 53.28 cM
Chr. · 2
Peroxiredoxin 1 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Peroxiredoxin 1 → 116,558,019 bp, 45,542,732 bp
related to Interactions · 2
Peroxiredoxin 1 → Peroxiredoxin, PRDX4
1.11.1.24 · 1
Peroxiredoxin 1 → ↗
Aliases · 1
Peroxiredoxin 1 → PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

peroxiredoxin human bp gene chr band protein chromosome prdx1 cancer role location may play activity mouse antioxidant function external pdb

Peroxiredoxin 1 relationships Subject–Predicate–Object triples

TTTA extracted 104 structured relationships around Peroxiredoxin 1. Examples in this analysis include Peroxiredoxin 1 → 1.11.1.24 → ↗ and Peroxiredoxin 1 → Aliases → PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Peroxiredoxin 11.11.1.24↗1.00infobox
Peroxiredoxin 1AliasesPRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 11.00infobox
Peroxiredoxin 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RII, 3HY2, 4XCS1.00infobox
Peroxiredoxin 1Band1p34.11.00infobox
Peroxiredoxin 1Band4 D1|4 53.28 cM1.00infobox
Peroxiredoxin 1Bgeeright lobe of thyroid gland1.00infobox
Peroxiredoxin 1Bgeeleft lobe of thyroid gland1.00infobox
Peroxiredoxin 1Bgeenasal epithelium1.00infobox
Peroxiredoxin 1Bgeeolfactory zone of nasal mucosa1.00infobox
Peroxiredoxin 1Bgeepalpebral conjunctiva1.00infobox
Peroxiredoxin 1BgeeC1 segment1.00infobox
Peroxiredoxin 1Bgeemucosa of esophagus1.00infobox
Peroxiredoxin 1Bgeeganglionic eminence1.00infobox
Peroxiredoxin 1Bgeegums1.00infobox
Peroxiredoxin 1Bgeegingival epithelium1.00infobox
Peroxiredoxin 1Bgeevas deferens1.00infobox
Peroxiredoxin 1Bgeeprimitive streak1.00infobox
Peroxiredoxin 1Bgeeendothelial cell of lymphatic vessel1.00infobox
Peroxiredoxin 1Bgeeright kidney1.00infobox
Peroxiredoxin 1BgeeGonadal ridge1.00infobox
Peroxiredoxin 1Bgeeefferent ductule1.00infobox
Peroxiredoxin 1Bgeelobe of prostate1.00infobox
Peroxiredoxin 1Bgeestroma of bone marrow1.00infobox
Peroxiredoxin 1Bgeeiris1.00infobox
Peroxiredoxin 1Bgeeepiblast1.00infobox
Peroxiredoxin 1BioGPSMore reference expression data1.00infobox
Peroxiredoxin 1Chr.Chromosome 1 (human)1.00infobox
Peroxiredoxin 1Chr.Chromosome 4 (mouse)1.00infobox
Peroxiredoxin 1DatabasesNCBI: entry; OMA: entry1.00infobox
Peroxiredoxin 1End45,542,732 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Peroxiredoxin 1 bring nearby vocabulary together. In this analysis, examples include Human, Act and Shown. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Prdx1
    • Chromosome
    • Bp
    • Chr
    • Protein
    • D1
    • End
    • Function
    • Mouse
    • Search
    • Human
  • function
    • Search
    • Activity
    • Location
    • Prdx1
    • Chromosome
    • Bp
    • Chr
    • Gene
    • Antioxidant
    • Available
    • Cell
    • D1
  • Peroxiredoxin 1
    • Human
    • Act
    • Shown
    • Cancer
    • Cell
    • Expression
    • Search
    • Location
    • Prdx1
    • May
    • Role
    • Antioxidant
  • peroxiredoxin 1
    • Human
    • Act
    • Shown
    • Cancer
    • Cell
    • Expression
    • Search
    • Location
    • Prdx1
    • May
    • Role
    • Antioxidant
  • peroxiredoxin
    • Human
    • Act
    • Shown
    • Cancer
    • Cell
    • Expression
    • Search
    • Location
    • Prdx1
    • May
    • Role
    • Antioxidant
  • cancer
    • Act
    • Human
    • Peroxiredoxin
    • Development
    • Expression
    • May
    • Play
    • Protein
    • Role
  • protein
    • May
    • Play
    • Role
    • Q06830
    • Search
    • Uniprot
    • Cancer

Connections between topic areas Semantic bridges

For Peroxiredoxin 1, one of the stronger structural bridges in this analysis connects Peroxiredoxin 1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Peroxiredoxin 1 — Clinical significance · splits 10 ⟂ 5
Peroxiredoxin 1 — Interactions · splits 11 ⟂ 4
Peroxiredoxin 1 — Overview · splits 12 ⟂ 3

Map overview Semantic statistics

Peroxiredoxin 1

Nodes15
Edges14
Triples104
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around Peroxiredoxin 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Peroxiredoxin 1 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.

Monitor your Domain Rating with FrogDR