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Peroxiredoxin 1

Peroxiredoxin-1 is a protein that in humans is encoded by the PRDX1 gene.

Clinical significance, Interactions & Function

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Clinical significance

4 related topics

Interactions

3 related topics

Function

1 related topics

Overview

2 related topics

Key facts & relationships

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1.11.1.24
Aliases
PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RII, 3HY2, 4XCS
Band
1p34.1 · 4 D1|4 53.28 cM
Bgee
right lobe of thyroid gland · left lobe of thyroid gland · nasal epithelium · olfactory zone of nasal mucosa · palpebral conjunctiva
BioGPS
More reference expression data

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Overview

Function

Interactions

Clinical significance

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Map overview Semantic statistics

Peroxiredoxin 1

Nodes15
Edges14
Triples108
Avg. degree1.87
Density0.133333
Components1

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Peroxiredoxin 1

Top relations

Gene ontology · 33
Peroxiredoxin 1 → antioxidant activity, cadherin binding, cell population proliferation, cell redox homeostasis, cellular response to oxidative stress, cytoplasm, cytosol, erythrocyte homeostasis, extracellular exosome, extracellular matrix, extracellular space, hydrogen peroxide catabolic process, identical protein binding, leukocyte activation, melanosome, mitochondrion, myelin sheath, natural killer cell activation, natural killer cell mediated cytotoxicity, nucleus
Bgee · 20
Peroxiredoxin 1 → C1 segment, efferent ductule, endothelial cell of lymphatic vessel, epiblast, ganglionic eminence, gingival epithelium, Gonadal ridge, gums, iris, left lobe of thyroid gland, lobe of prostate, mucosa of esophagus, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, primitive streak, right kidney, right lobe of thyroid gland, stroma of bone marrow, vas deferens
RNA expression pattern · 20
Peroxiredoxin 1 → C1 segment, efferent ductule, endothelial cell of lymphatic vessel, epiblast, ganglionic eminence, gingival epithelium, Gonadal ridge, gums, iris, left lobe of thyroid gland, lobe of prostate, mucosa of esophagus, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, primitive streak, right kidney, right lobe of thyroid gland, stroma of bone marrow, vas deferens
related to Clinical significance · 7
Peroxiredoxin 1 → As, In, It, LPS, Peroxiredoxin, The, TNF-alpha
Band · 2
Peroxiredoxin 1 → 1p34.1, 4 D1|4 53.28 cM
Chr. · 2
Peroxiredoxin 1 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Peroxiredoxin 1 → 116,558,019 bp, 45,542,732 bp
related to Interactions · 2
Peroxiredoxin 1 → Peroxiredoxin, PRDX4
1.11.1.24 · 1
Peroxiredoxin 1 → ↗
Aliases · 1
Peroxiredoxin 1 → PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1

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Important terminology

peroxiredoxin human bp gene chr band protein chromosome prdx1 cancer role location may play activity mouse antioxidant function external pdb

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Peroxiredoxin 11.11.1.241.00infobox
Peroxiredoxin 1AliasesPRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 11.00infobox
Peroxiredoxin 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RII, 3HY2, 4XCS1.00infobox
Peroxiredoxin 1Band1p34.11.00infobox
Peroxiredoxin 1Band4 D1|4 53.28 cM1.00infobox
Peroxiredoxin 1Bgeeright lobe of thyroid gland1.00infobox
Peroxiredoxin 1Bgeeleft lobe of thyroid gland1.00infobox
Peroxiredoxin 1Bgeenasal epithelium1.00infobox
Peroxiredoxin 1Bgeeolfactory zone of nasal mucosa1.00infobox
Peroxiredoxin 1Bgeepalpebral conjunctiva1.00infobox
Peroxiredoxin 1BgeeC1 segment1.00infobox
Peroxiredoxin 1Bgeemucosa of esophagus1.00infobox
Peroxiredoxin 1Bgeeganglionic eminence1.00infobox
Peroxiredoxin 1Bgeegums1.00infobox
Peroxiredoxin 1Bgeegingival epithelium1.00infobox
Peroxiredoxin 1Bgeevas deferens1.00infobox
Peroxiredoxin 1Bgeeprimitive streak1.00infobox
Peroxiredoxin 1Bgeeendothelial cell of lymphatic vessel1.00infobox
Peroxiredoxin 1Bgeeright kidney1.00infobox
Peroxiredoxin 1BgeeGonadal ridge1.00infobox
Peroxiredoxin 1Bgeeefferent ductule1.00infobox
Peroxiredoxin 1Bgeelobe of prostate1.00infobox
Peroxiredoxin 1Bgeestroma of bone marrow1.00infobox
Peroxiredoxin 1Bgeeiris1.00infobox
Peroxiredoxin 1Bgeeepiblast1.00infobox
Peroxiredoxin 1BioGPSMore reference expression data1.00infobox
Peroxiredoxin 1Chr.Chromosome 1 (human)1.00infobox
Peroxiredoxin 1Chr.Chromosome 4 (mouse)1.00infobox
Peroxiredoxin 1DatabasesNCBI: entry; OMA: entry1.00infobox
Peroxiredoxin 1End45,542,732 bp1.00infobox

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