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Phorbol-12-myristate-13-acetate-induced protein 1

Phorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the PMAIP1 gene, and is also known as Noxa.

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Aliases
PMAIP1, APR, NOXA, phorbol-12-myristate-13-acetate-induced protein 1
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3MQP
Band
18q21.32
Bgee
buccal mucosa cell · cartilage tissue · oral cavity · gonad · monocyte
BioGPS
More reference expression data
Chr.
Chromosome 18 (human)

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Phorbol-12-myristate-13-acetate-induced protein 1

Nodes14
Edges13
Triples72
Avg. degree1.86
Density0.142857
Components1

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Phorbol-12-myristate-13-acetate-induced protein 1

Top relations

Gene ontology · 32
Phorbol-12-myristate-13-acetate-induced protein 1 → activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to DNA damage stimulus, cellular response to glucose starvation, cellular response to hypoxia, cytosol, defense response to virus, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, mitochondrial outer membrane, mitochondrion, negative regulation of mitochondrial membrane potential, nucleus, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of glucose metabolic process, positive regulation of intrinsic apoptotic signaling pathway
Bgee · 10
Phorbol-12-myristate-13-acetate-induced protein 1 → bone marrow, buccal mucosa cell, cartilage tissue, gonad, human penis, monocyte, nipple, oral cavity, palpebral conjunctiva, skin of thigh
RNA expression pattern · 10
Phorbol-12-myristate-13-acetate-induced protein 1 → bone marrow, buccal mucosa cell, cartilage tissue, gonad, human penis, monocyte, nipple, oral cavity, palpebral conjunctiva, skin of thigh
Aliases · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → PMAIP1, APR, NOXA, phorbol-12-myristate-13-acetate-induced protein 1
Available structures · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3MQP
Band · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → 18q21.32
BioGPS · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → More reference expression data
Chr. · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → Chromosome 18 (human)
Databases · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → NCBI: entry; OMA: entry
End · 1
Phorbol-12-myristate-13-acetate-induced protein 1 → 59,904,306 bp

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Important terminology

noxa protein bcl-2 human pmaip1 involved bp gene p53 chr chromosome 18 pro-apoptotic family also uniprot band apoptosis phorbol-12-myristate-13-acetate-induced damage

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Phorbol-12-myristate-13-acetate-induced protein 1AliasesPMAIP1, APR, NOXA, phorbol-12-myristate-13-acetate-induced protein 11.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Available structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3MQP1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Band18q21.321.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeebuccal mucosa cell1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeecartilage tissue1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeeoral cavity1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeegonad1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeemonocyte1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeeskin of thigh1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeenipple1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeehuman penis1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeebone marrow1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Bgeepalpebral conjunctiva1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1BioGPSMore reference expression data1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Chr.Chromosome 18 (human)1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1DatabasesNCBI: entry; OMA: entry1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1End59,904,306 bp1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1EnsemblENSG000001416821.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Entrez53661.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1External IDsOMIM: 604959; GeneCards: PMAIP11.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene location (Human)Gene location (Human)Chr.Chromosome 18 (human)Band18q21.32Start59,899,948 bpEnd59,904,306 bp1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologyprotein binding1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologycytosol1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologymitochondrial outer membrane1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologymitochondrion1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologynucleus1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologypositive regulation of extrinsic apoptotic signaling pathway via death domain receptors1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologyresponse to dsRNA1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologycellular response to glucose starvation1.00infobox
Phorbol-12-myristate-13-acetate-induced protein 1Gene ontologypositive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway1.00infobox

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