PIEZO2

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PIEZO2 topic overview

The analysis highlights Function, Structure and Pathology as prominent areas in the source structure around PIEZO2.

Related topics: 37
Source areas: 4
Connected nodes: 41
Extracted relationships: 107
Concept neighborhoods: 15
Bridge connections: 41

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 19 topics

Overview · 10 topics

Pathology · 4 topics

Structure · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: PIEZO2, C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS, piezo type mechanosensitive ion channel component 2, DAIPT
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes6KG7
Band: 18p11.22-p11.21 · 18|18 E1
Bgee: sural nerve · corpus callosum · spinal ganglia · visceral pleura · inferior ganglion of vagus nerve
BioGPS: n/a
Chr.: Chromosome 18 (human) · Chromosome 18 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Pathology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PIEZO2 connects Entity context

The extracted context around PIEZO2 shows recurring relationship patterns in the source. For example, PIEZO2 → Achilles tendon, aortic valve, ascending aorta, C1 segment, corpus callosum, cumulus cell, gastrula, genital tubercle, hand, inferior ganglion of vagus nerve, lobe of prostate, lumbar spinal ganglion, optic nerve, parietal pleura, prostate, spinal ganglia, sural nerve, trigeminal ganglion, visceral pleura Another extracted example is PIEZO2 → cation channel activity, cation transmembrane transport, cation transport, cellular response to mechanical stimulus, detection of mechanical stimulus, detection of mechanical stimulus involved in sensory perception, integral component of membrane, ion transmembrane transport, ion transport, mechanosensitive ion channel activity, membrane, plasma membrane, regulation of membrane potential, response to mechanical stimulus, response to stimulus, transmembrane transport. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Bgee · 19

PIEZO2 → Achilles tendon, aortic valve, ascending aorta, C1 segment, corpus callosum, cumulus cell, gastrula, genital tubercle, hand, inferior ganglion of vagus nerve, lobe of prostate, lumbar spinal ganglion, optic nerve, parietal pleura, prostate, spinal ganglia, sural nerve, trigeminal ganglion, visceral pleura

RNA expression pattern · 19

Gene ontology · 16

PIEZO2 → cation channel activity, cation transmembrane transport, cation transport, cellular response to mechanical stimulus, detection of mechanical stimulus, detection of mechanical stimulus involved in sensory perception, integral component of membrane, ion transmembrane transport, ion transport, mechanosensitive ion channel activity, membrane, plasma membrane, regulation of membrane potential, response to mechanical stimulus, response to stimulus, transmembrane transport

related to Pathology · 8

PIEZO2 → Arthrogryposis, Distal Arthrogryposis, Distal Arthrogryposis Type, Gain-of-function, Gordon, Loss, Marden-Walker, Mice

related to Physiological function · 6

PIEZO2 → Along, For, In, It, Merkel, PIEZO1

related to Structure · 6

PIEZO2 → Each, Piezo, Piezos, The, They, Under

related to Molecular function · 3

PIEZO2 → PIEZO1, PIEZO2-mediated, The

Band · 2

PIEZO2 → 18p11.22-p11.21, 18|18 E1

Chr. · 2

PIEZO2 → Chromosome 18 (human), Chromosome 18 (mouse)

End · 2

PIEZO2 → 11,149,569 bp, 63,520,254 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

channel ion bp membrane chr human band protein role gene structure piezo1 chromosome 18 mouse mechanical nm mechanosensitive blades component

PIEZO2 relationships Subject–Predicate–Object triples

TTTA extracted 107 structured relationships around PIEZO2. Examples in this analysis include PIEZO2 → Aliases → PIEZO2, C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS, piezo type mechanosensitive ion channel component 2, DAIPT and PIEZO2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes6KG7. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
PIEZO2	Aliases	PIEZO2, C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS, piezo type mechanosensitive ion channel component 2, DAIPT	1.00	infobox
PIEZO2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes6KG7	1.00	infobox
PIEZO2	Band	18p11.22-p11.21	1.00	infobox
PIEZO2	Band	18\|18 E1	1.00	infobox
PIEZO2	Bgee	sural nerve	1.00	infobox
PIEZO2	Bgee	corpus callosum	1.00	infobox
PIEZO2	Bgee	spinal ganglia	1.00	infobox
PIEZO2	Bgee	visceral pleura	1.00	infobox
PIEZO2	Bgee	inferior ganglion of vagus nerve	1.00	infobox
PIEZO2	Bgee	trigeminal ganglion	1.00	infobox
PIEZO2	Bgee	parietal pleura	1.00	infobox
PIEZO2	Bgee	optic nerve	1.00	infobox
PIEZO2	Bgee	C1 segment	1.00	infobox
PIEZO2	Bgee	Achilles tendon	1.00	infobox
PIEZO2	Bgee	lumbar spinal ganglion	1.00	infobox
PIEZO2	Bgee	prostate	1.00	infobox
PIEZO2	Bgee	lobe of prostate	1.00	infobox
PIEZO2	Bgee	cumulus cell	1.00	infobox
PIEZO2	Bgee	genital tubercle	1.00	infobox
PIEZO2	Bgee	hand	1.00	infobox
PIEZO2	Bgee	aortic valve	1.00	infobox
PIEZO2	Bgee	ascending aorta	1.00	infobox
PIEZO2	Bgee	gastrula	1.00	infobox
PIEZO2	BioGPS	n/a	1.00	infobox
PIEZO2	Chr.	Chromosome 18 (human)	1.00	infobox
PIEZO2	Chr.	Chromosome 18 (mouse)	1.00	infobox
PIEZO2	Databases	NCBI: entry; OMA: entry	1.00	infobox
PIEZO2	End	11,149,569 bp	1.00	infobox
PIEZO2	End	63,520,254 bp	1.00	infobox
PIEZO2	Ensembl	ENSG00000154864	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PIEZO2 bring nearby vocabulary together. In this analysis, examples include Cells, Expressed and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

PIEZO2
- Cells
- Expressed
- Protein
- Role
- Activated
- Mechanically
- Piezo1
- Molecular
- Function
- Location
- Mouse
- Proprioception
piezo2
- Cells
- Expressed
- Protein
- Role
- Activated
- Mechanically
- Piezo1
- Molecular
- Function
- Location
- Mouse
- Proprioception
mechanosensitive
- Gene
- Molecular
- Function
- Location
- Chromosome
- Human
- Nm
- Protein
- Bp
- Chr
- Species
- Mouse
gene
- Location
- Mechanosensitive
- Chromosome
- Human
- Bp
- Chr
- Molecular
- Ion
- Function
- Mouse
- Band
- Nm
transmembrane proteins
- Species
- Protein
- Molecular
- Component
- Form
- Function
- Location
- Mechanosensitive
- Mouse
- Plasma
- Proteins
- Transmembrane
transmembrane domains
- Protein
- Molecular
- Species
- Component
- Form
- Function
- Location
- Mechanosensitive
- Mouse
- Plasma
- Proteins
- Band
function
- Molecular
- Location
- Mechanosensitive
- Chromosome
- Gene
- Human
- Nm
- Bp
- Chr
- Ion
- Species
- Mouse
plasma membrane
- Plasma
- Form
- Species
- Proteins
- Transmembrane
- Protein
- Molecular
- Function
- Location
- Mouse
- Nano-dome
- Three

Connections between topic areas Semantic bridges

For PIEZO2, one of the stronger structural bridges in this analysis connects PIEZO2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

PIEZO2 — Function · splits 22 ⟂ 20

PIEZO2 — Overview · splits 31 ⟂ 11

PIEZO2 — Structure · splits 37 ⟂ 5

PIEZO2 — Pathology · splits 37 ⟂ 5

Map overview Semantic statistics

PIEZO2

Nodes42

Edges41

Triples107

Avg. degree1.95

Density0.047619

Components1

Source & methodology

TTTA analyzes the structure around PIEZO2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Pathology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PIEZO2 · EN edition · Analysis: TopicsToTalkAbout