PIEZO2

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Explore the main themes, entities and connections around PIEZO2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Calcium Patch clamp Picosiemens Touch Proprioception

19 related topics

Structure

Transmembrane proteins Cryo-electron microscopy Transmembrane domains Curvature

4 related topics

Pathology

Arthrogryposis Gordon syndrome Marden-Walker syndrome Perinatal

4 related topics

Overview

Mechanosensitive Protein Gene Mechanotransduction Depolarization

10 related topics

Key facts & relationships

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Aliases: PIEZO2, C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS, piezo type mechanosensitive ion channel component 2, DAIPT
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes6KG7
Band: 18p11.22-p11.21 · 18|18 E1
Bgee: sural nerve · corpus callosum · spinal ganglia · visceral pleura · inferior ganglion of vagus nerve
BioGPS: n/a
Chr.: Chromosome 18 (human) · Chromosome 18 (mouse)

Topics to explore

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Pathology

Advanced semantic analysis

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Map overview Semantic statistics

Nodes42

Edges41

Triples107

Avg. degree1.95

Density0.047619

Components1

How this topic connects Entity context

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PIEZO2

Top relations

Bgee · 19

PIEZO2 → Achilles tendon, aortic valve, ascending aorta, C1 segment, corpus callosum, cumulus cell, gastrula, genital tubercle, hand, inferior ganglion of vagus nerve, lobe of prostate, lumbar spinal ganglion, optic nerve, parietal pleura, prostate, spinal ganglia, sural nerve, trigeminal ganglion, visceral pleura

RNA expression pattern · 19

Gene ontology · 16

PIEZO2 → cation channel activity, cation transmembrane transport, cation transport, cellular response to mechanical stimulus, detection of mechanical stimulus, detection of mechanical stimulus involved in sensory perception, integral component of membrane, ion transmembrane transport, ion transport, mechanosensitive ion channel activity, membrane, plasma membrane, regulation of membrane potential, response to mechanical stimulus, response to stimulus, transmembrane transport

related to Pathology · 8

PIEZO2 → Arthrogryposis, Distal Arthrogryposis, Distal Arthrogryposis Type, Gain-of-function, Gordon, Loss, Marden-Walker, Mice

related to Physiological function · 6

PIEZO2 → Along, For, In, It, Merkel, PIEZO1

related to Structure · 6

PIEZO2 → Each, Piezo, Piezos, The, They, Under

related to Molecular function · 3

PIEZO2 → PIEZO1, PIEZO2-mediated, The

Band · 2

PIEZO2 → 18p11.22-p11.21, 18|18 E1

Chr. · 2

PIEZO2 → Chromosome 18 (human), Chromosome 18 (mouse)

End · 2

PIEZO2 → 11,149,569 bp, 63,520,254 bp

Important terminology Word statistics

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Important terminology

channel ion bp membrane chr human band protein role gene structure piezo1 chromosome 18 mouse mechanical nm mechanosensitive blades component

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PIEZO2	Aliases	PIEZO2, C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS, piezo type mechanosensitive ion channel component 2, DAIPT	1.00	infobox
PIEZO2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes6KG7	1.00	infobox
PIEZO2	Band	18p11.22-p11.21	1.00	infobox
PIEZO2	Band	18\|18 E1	1.00	infobox
PIEZO2	Bgee	sural nerve	1.00	infobox
PIEZO2	Bgee	corpus callosum	1.00	infobox
PIEZO2	Bgee	spinal ganglia	1.00	infobox
PIEZO2	Bgee	visceral pleura	1.00	infobox
PIEZO2	Bgee	inferior ganglion of vagus nerve	1.00	infobox
PIEZO2	Bgee	trigeminal ganglion	1.00	infobox
PIEZO2	Bgee	parietal pleura	1.00	infobox
PIEZO2	Bgee	optic nerve	1.00	infobox
PIEZO2	Bgee	C1 segment	1.00	infobox
PIEZO2	Bgee	Achilles tendon	1.00	infobox
PIEZO2	Bgee	lumbar spinal ganglion	1.00	infobox
PIEZO2	Bgee	prostate	1.00	infobox
PIEZO2	Bgee	lobe of prostate	1.00	infobox
PIEZO2	Bgee	cumulus cell	1.00	infobox
PIEZO2	Bgee	genital tubercle	1.00	infobox
PIEZO2	Bgee	hand	1.00	infobox
PIEZO2	Bgee	aortic valve	1.00	infobox
PIEZO2	Bgee	ascending aorta	1.00	infobox
PIEZO2	Bgee	gastrula	1.00	infobox
PIEZO2	BioGPS	n/a	1.00	infobox
PIEZO2	Chr.	Chromosome 18 (human)	1.00	infobox
PIEZO2	Chr.	Chromosome 18 (mouse)	1.00	infobox
PIEZO2	Databases	NCBI: entry; OMA: entry	1.00	infobox
PIEZO2	End	11,149,569 bp	1.00	infobox
PIEZO2	End	63,520,254 bp	1.00	infobox
PIEZO2	Ensembl	ENSG00000154864	1.00	infobox

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