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PICK1: Interactions, Function & Overview

Protein Interacting with C Kinase - 1 is a protein that in humans is encoded by the PICK1 gene.

Language: English [EN]
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PICK1 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around PICK1.

Related topics
16
Source areas
3
Connected nodes
19
Extracted relationships
124
Concept neighborhoods
10
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 13 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PICK1, PICK, PRKCABP, protein interacting with PRKCA 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GZV
Band
22q13.1 · 15|15 E1
Bgee
anterior pituitary · right hemisphere of cerebellum · right uterine tube · left ovary · right frontal lobe
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

Suggested research paths

A focused starting point derived from the topic graph, ranked independently of the source article order.

Start with these areas

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PICK1 connects Entity context

The extracted context around PICK1 shows recurring relationship patterns in the source. For example, PICK1 → actin binding, actin filament binding, aggresome, Arp2/3 complex binding, cell junction, cellular response to decreased oxygen levels, cellular response to glucose starvation, cytoplasm, cytoskeleton, cytosol, dendritic spine maintenance, dendritic spine organization, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, endocytic vesicle membrane, enzyme binding, G protein-coupled receptor binding, glial cell development, Golgi apparatus, identical protein binding Another extracted example is PICK1 → anterior pituitary, body of pancreas, crypt of lieberkuhn of small intestine, extensor digitorum longus muscle, gastric mucosa, left ovary, left testis, lip, muscle of thigh, neural layer of retina, right frontal lobe, right hemisphere of cerebellum, right kidney, right ovary, right testis, right uterine tube, spermatid, spermatocyte, superior frontal gyrus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

PICK1

Top relations

Gene ontology · 50
PICK1 → actin binding, actin filament binding, aggresome, Arp2/3 complex binding, cell junction, cellular response to decreased oxygen levels, cellular response to glucose starvation, cytoplasm, cytoskeleton, cytosol, dendritic spine maintenance, dendritic spine organization, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, endocytic vesicle membrane, enzyme binding, G protein-coupled receptor binding, glial cell development, Golgi apparatus, identical protein binding
Bgee · 20
PICK1 → anterior pituitary, body of pancreas, crypt of lieberkuhn of small intestine, extensor digitorum longus muscle, gastric mucosa, left ovary, left testis, lip, muscle of thigh, neural layer of retina, right frontal lobe, right hemisphere of cerebellum, right kidney, right ovary, right testis, right uterine tube, spermatid, spermatocyte, superior frontal gyrus, ventricular zone
RNA expression pattern · 20
PICK1 → anterior pituitary, body of pancreas, crypt of lieberkuhn of small intestine, extensor digitorum longus muscle, gastric mucosa, left ovary, left testis, lip, muscle of thigh, neural layer of retina, right frontal lobe, right hemisphere of cerebellum, right kidney, right ovary, right testis, right uterine tube, spermatid, spermatocyte, superior frontal gyrus, ventricular zone
related to Interactions · 11
PICK1 → ACCN2, BNC1, Dopamine, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, HER2/neu, Metabotropic
Band · 2
PICK1 → 15|15 E1, 22q13.1
Chr. · 2
PICK1 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
PICK1 → 38,075,701 bp, 79,133,684 bp
Aliases · 1
PICK1 → PICK1, PICK, PRKCABP, protein interacting with PRKCA 1
Available structures · 1
PICK1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GZV
BioGPS · 1
PICK1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein bp gene chr human band chromosome 22 prkca function kinase location membrane mouse receptor interacting external mgi genecards encoded

PICK1 relationships Subject–Predicate–Object triples

TTTA extracted 124 structured relationships around PICK1. Examples in this analysis include PICK1 → Aliases → PICK1, PICK, PRKCABP, protein interacting with PRKCA 1 and PICK1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GZV. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PICK1AliasesPICK1, PICK, PRKCABP, protein interacting with PRKCA 11.00infobox
PICK1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GZV1.00infobox
PICK1Band22q13.11.00infobox
PICK1Band15|15 E11.00infobox
PICK1Bgeeanterior pituitary1.00infobox
PICK1Bgeeright hemisphere of cerebellum1.00infobox
PICK1Bgeeright uterine tube1.00infobox
PICK1Bgeeleft ovary1.00infobox
PICK1Bgeeright frontal lobe1.00infobox
PICK1Bgeeleft testis1.00infobox
PICK1Bgeeright testis1.00infobox
PICK1Bgeegastric mucosa1.00infobox
PICK1Bgeeright ovary1.00infobox
PICK1Bgeebody of pancreas1.00infobox
PICK1Bgeeneural layer of retina1.00infobox
PICK1Bgeespermatid1.00infobox
PICK1Bgeemuscle of thigh1.00infobox
PICK1Bgeespermatocyte1.00infobox
PICK1Bgeesuperior frontal gyrus1.00infobox
PICK1Bgeeright kidney1.00infobox
PICK1Bgeelip1.00infobox
PICK1Bgeecrypt of lieberkuhn of small intestine1.00infobox
PICK1Bgeeextensor digitorum longus muscle1.00infobox
PICK1Bgeeventricular zone1.00infobox
PICK1BioGPSMore reference expression data1.00infobox
PICK1Chr.Chromosome 22 (human)1.00infobox
PICK1Chr.Chromosome 15 (mouse)1.00infobox
PICK1DatabasesNCBI: entry; OMA: entry1.00infobox
PICK1End38,075,701 bp1.00infobox
PICK1End79,133,684 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PICK1 bring nearby vocabulary together. In this analysis, examples include Gene, Search and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PICK1
    • Gene
    • Search
    • Protein
    • Location
    • Receptor
    • Chromosome
    • Function
    • Human
    • Prkca
    • Bp
    • Chr
    • Domain
  • pick1
    • Gene
    • Search
    • Protein
    • Location
    • Receptor
    • Chromosome
    • Function
    • Human
    • Prkca
    • Bp
    • Chr
    • Domain
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Pick1
    • Bp
    • Chr
    • End
    • Interacting
    • Kinase
    • Mouse
    • Search
  • function
    • Membrane
    • Prkca
    • May
    • Monoamine
    • Plasma
    • Proteins
    • Search
    • Protein
    • Location
    • Receptor
    • Chromosome
    • Human
  • prkca
    • Monoamine
    • Plasma
    • Search
    • Protein
    • Membrane
    • Receptor
    • Domain
    • End
    • Found
    • Glutamate
    • Interact
    • May
  • protein
    • Found
    • Search
    • Membrane
    • Domain
    • End
    • May
    • Monoamine
    • Mouse
    • Plasma
    • Proteins
    • Receptor
    • Band
  • metabotropic glutamate receptor 3
    • Interact
    • Shown
    • Glutamate
    • Receptor
    • May
    • Monoamine
    • Plasma
    • Proteins
    • Membrane
    • Search
    • Pick1
    • Prkca
  • metabotropic glutamate receptor 7
    • Interact
    • Shown
    • Glutamate
    • Receptor
    • May
    • Monoamine
    • Plasma
    • Proteins
    • Membrane
    • Search
    • Pick1
    • Prkca

Connections between topic areas Semantic bridges

For PICK1, one of the stronger structural bridges in this analysis connects PICK1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PICK1Interactions · splits 6 ⟂ 14
PICK1Overview · splits 17 ⟂ 3

Map overview Semantic statistics

PICK1

Nodes20
Edges19
Triples124
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around PICK1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PICK1 · EN edition · Analysis: TopicsToTalkAbout

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