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Phagosome

In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis. Professional phagocytes include macrophages, neutrophils, and dendritic cells (DCs).

Art, Formation & Function

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Overview

Formation

Structure

Maturation process

Function

Bacterial evasion and manipulation

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Map overview Semantic statistics

Phagosome

Nodes117
Edges116
Triples153
Avg. degree1.98
Density0.017094
Components1

How this topic connects Entity context

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Phagosome

Top relations

related to Bacterial evasion and manipulation · 14
Phagosome → ERGIC, In, Legionella, Legionella-containing, Listeria, Listeriolysin, M2, Many, Mycobacterium, PtpA, ROS, SapM, The, This
related to Inflammation · 13
Phagosome → CR-mediated, FcR, IL-12, IL-1β, IL-6, MAP, Pathogen-infected, PI-3, PLC, Pro-inflammatory, Rho GTPases, The, TNFα
related to Fusion regulation · 12
Phagosome → CORVET, F-actin, GDI, HOPS, PI-3, Rab GTPases, Rab11, Rab5, Rab7, Shortly, The, Vps34
related to Formation · 11
Phagosome → CR, Fc, FcR, More, Other, Phagosomes, PLC, Protein, This, Toll-like, Upon
related to Maturation process · 11
Phagosome → As, ATPase, Enzyme, FcR, Fusion, It, Larger, Mycobacterium, The, This, Vacuolar
related to Opsonisation · 11
Phagosome → Complement-mediated, Fab, Fc, FcR, IgG, Immunoglobulin, It, Opsonins, Rho GTPases, The, They
related to Antigen presentation · 10
Phagosome → DCs, Immature, MHC, Peptides, Rho GTPases, T-cell, T-cells, The, They, This
related to Autophagosome · 9
Phagosome → Autophagosomes, Autophagy, Christian, Duve, ER-Golgi, ERGIC, However, The, When
related to Phagolysosome · 8
Phagosome → Also, ATPases, M1, M2, RNS, ROS, The, Those
related to Structure · 8
Phagosome → As, By, Early, Endosomes, Phagosomes, Rab5, Rab7, They

Important terminology Word statistics

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Important terminology

phagosomes cells membrane lysosomes also phagocytosis macrophages pathogens cell maturation proteins phagocytes process fusion phagolysosome fuse formed apoptotic bacteria protein

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Phagosomeis avesicle formed around a particle engulfed by a phagocyte via phagocytosis0.90text
fibroblastsinstance ofwhich means that they can induce phagocytosis if they are expressed in non-phagocytic cells0.80text
Toll-like receptors are involved in pathogen pattern recognitioninstance ofOther proteins0.80text
are often recruited to phagosomes but do not specifically trigger phagocytosis in non-phagocytic cellsinstance ofOther proteins0.80text
so they are not considered phagocytic receptors.OpsonisationOpsonins are molecular tags such as antibodiesinstance ofOther proteins0.80text
complements that attach to pathogensinstance ofOther proteins0.80text
up-regulate phagocytosisinstance ofOther proteins0.80text
FcRinstance ofHowever non-professional phagocytes do not express specific phagocytic receptors0.80text
have a much lower rate of internalisation.Some invasive bacteria can also induce phagocytosis in non-phagocytic cells to mediate host uptakeinstance ofHowever non-professional phagocytes do not express specific phagocytic receptors0.80text
antibodiesinstance ofOpsonisationOpsonins are molecular tags0.80text
complements that attach to pathogensinstance ofOpsonisationOpsonins are molecular tags0.80text
up-regulate phagocytosisinstance ofOpsonisationOpsonins are molecular tags0.80text

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