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ORC2: Measurement, Interactions & Function

Origin recognition complex subunit 2 is a protein that is encoded by the ORC2 (ORC2L) gene in humans.

Language: English [EN]
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ORC2 topic overview

The analysis highlights Measurement, Interactions and Function as prominent areas in the source structure around ORC2. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
19
Source areas
3
Connected nodes
23
Extracted relationships
97
Concept neighborhoods
12
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 12 topics
Function · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ORC2, ORC2L, origin recognition complex subunit 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5C8H
Band
2q33.1 · 1|1 C1.3
Bgee
Achilles tendon · sural nerve · epithelium of colon · buccal mucosa cell · gastric mucosa
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ORC2 connects Entity context

The extracted context around ORC2 shows recurring relationship patterns in the source. For example, ORC2 → Achilles tendon, body of pancreas, buccal mucosa cell, epiblast, epithelium of colon, fetal liver hematopoietic progenitor cell, gastric mucosa, genital tubercle, left testis, medullary collecting duct, Paneth cell, primitive streak, right testis, secondary oocyte, skin of leg, spermatid, spermatocyte, sural nerve, tail of embryo, ventricular zone Another extracted example is ORC2 → centrosome, chromatin, DNA replication, DNA replication initiation, DNA replication origin binding, G1 phase, G1/S transition of mitotic cell cycle, heterochromatin, inner kinetochore, membrane, negative regulation of transcription by RNA polymerase II, nuclear origin of replication recognition complex, nucleoplasm, nucleus, origin recognition complex, protein binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

ORC2

Top relations

Bgee · 20
ORC2 → Achilles tendon, body of pancreas, buccal mucosa cell, epiblast, epithelium of colon, fetal liver hematopoietic progenitor cell, gastric mucosa, genital tubercle, left testis, medullary collecting duct, Paneth cell, primitive streak, right testis, secondary oocyte, skin of leg, spermatid, spermatocyte, sural nerve, tail of embryo, ventricular zone
RNA expression pattern · 20
ORC2 → Achilles tendon, body of pancreas, buccal mucosa cell, epiblast, epithelium of colon, fetal liver hematopoietic progenitor cell, gastric mucosa, genital tubercle, left testis, medullary collecting duct, Paneth cell, primitive streak, right testis, secondary oocyte, skin of leg, spermatid, spermatocyte, sural nerve, tail of embryo, ventricular zone
Gene ontology · 16
ORC2 → centrosome, chromatin, DNA replication, DNA replication initiation, DNA replication origin binding, G1 phase, G1/S transition of mitotic cell cycle, heterochromatin, inner kinetochore, membrane, negative regulation of transcription by RNA polymerase II, nuclear origin of replication recognition complex, nucleoplasm, nucleus, origin recognition complex, protein binding
related to Interactions · 13
ORC2 → A1, CDC6, DBF4, MCM10, MCM2MCM4, MCM5, MCM6, MCM7, ORC1, ORC3, ORC4, ORC5, ORC6
related to External links · 3
ORC2 → Human Origin, PDB, PDBe-KB
Band · 2
ORC2 → 1|1 C1.3, 2q33.1
Chr. · 2
ORC2 → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
ORC2 → 200,963,680 bp, 58,544,268 bp
Aliases · 1
ORC2 → ORC2, ORC2L, origin recognition complex subunit 2
Available structures · 1
ORC2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5C8H

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human complex bp protein origin gene chr band recognition replication chromosome subunit dna initiation location mouse orc2l function external orc

ORC2 relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around ORC2. Examples in this analysis include ORC2 → Aliases → ORC2, ORC2L, origin recognition complex subunit 2 and ORC2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5C8H. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ORC2AliasesORC2, ORC2L, origin recognition complex subunit 21.00infobox
ORC2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5C8H1.00infobox
ORC2Band2q33.11.00infobox
ORC2Band1|1 C1.31.00infobox
ORC2BgeeAchilles tendon1.00infobox
ORC2Bgeesural nerve1.00infobox
ORC2Bgeeepithelium of colon1.00infobox
ORC2Bgeebuccal mucosa cell1.00infobox
ORC2Bgeegastric mucosa1.00infobox
ORC2Bgeebody of pancreas1.00infobox
ORC2Bgeesecondary oocyte1.00infobox
ORC2Bgeeskin of leg1.00infobox
ORC2Bgeeright testis1.00infobox
ORC2Bgeeleft testis1.00infobox
ORC2Bgeespermatocyte1.00infobox
ORC2Bgeefetal liver hematopoietic progenitor cell1.00infobox
ORC2Bgeetail of embryo1.00infobox
ORC2Bgeemedullary collecting duct1.00infobox
ORC2Bgeeventricular zone1.00infobox
ORC2Bgeeepiblast1.00infobox
ORC2Bgeespermatid1.00infobox
ORC2Bgeegenital tubercle1.00infobox
ORC2BgeePaneth cell1.00infobox
ORC2Bgeeprimitive streak1.00infobox
ORC2BioGPSMore reference expression data1.00infobox
ORC2Chr.Chromosome 2 (human)1.00infobox
ORC2Chr.Chromosome 1 (mouse)1.00infobox
ORC2DatabasesNCBI: entry; OMA: entry1.00infobox
ORC2End200,963,680 bp1.00infobox
ORC2End58,544,268 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ORC2 bring nearby vocabulary together. In this analysis, examples include Recognition, Origin and Subunit. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ORC2
    • Recognition
    • Origin
    • Subunit
    • Gene
    • Available
    • Function
    • Orc2l
    • Pdb
    • Search
    • Human
    • Protein
    • Location
  • orc2
    • Recognition
    • Origin
    • Subunit
    • Gene
    • Available
    • Function
    • Orc2l
    • Pdb
    • Search
    • Human
    • Protein
    • Location
  • protein
    • Replication
    • Cells
    • Orc3
    • Orc4
    • Orc5
    • Dna
    • Orc
    • Recognition
    • Subunit
    • Human
    • C1
    • Cdc6
  • gene
    • Location
    • Chromosome
    • Recognition
    • Subunit
    • Bp
    • Chr
    • Orc2
    • Origin
    • C1
    • End
    • Function
    • Mouse
  • origin recognition complex
    • Recognition
    • Orc2
    • Subunit
    • Complex
    • Gene
    • Human
    • Origin
    • Available
    • Function
    • Pdb
    • Protein
    • Search
  • replication protein a1
    • Cdc6
    • Demonstrated
    • Mcm10
    • Specifically
    • Replication
    • Cells
    • Orc3
    • Orc4
    • Orc5
    • Dna
    • Orc
    • Recognition
  • function
    • Search
    • Location
    • Chromosome
    • Recognition
    • Bp
    • Chr
    • Gene
    • Orc2
    • Origin
    • Available
    • C1
    • Cells
  • cdc6
    • Replication
    • Demonstrated
    • Mcm10
    • Orc3
    • Orc4
    • Orc5
    • Specifically
    • Initiation
    • Orc
    • Orc2
    • Protein

Connections between topic areas Semantic bridges

For ORC2, one of the stronger structural bridges in this analysis connects ORC2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ORC2Interactions · splits 11 ⟂ 13
ORC2Function · splits 17 ⟂ 7
ORC2Overview · splits 21 ⟂ 3

Map overview Semantic statistics

ORC2

Nodes24
Edges23
Triples97
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around ORC2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ORC2 · EN edition · Analysis: TopicsToTalkAbout

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