Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Nucleosome

A nucleosome is the basic structural unit of DNA packaging in eukaryotes. The structure of a nucleosome consists of a segment of DNA wound around eight histone proteins and resembles thread wrapped around a spool. The nucleosome is the fundamental subunit of chromatin. Each nucleosome is composed of a little less than two turns of DNA wrapped around a…

Regions & Measurement

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Nucleosome. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Modulating nucleosome structure

Gene silencingMethylationUbiquitinationLysineArginine
22 related topics

Overview

DNAEukaryotesHistoneSpoolChromatin
39 related topics

Dynamics

Cooperative bindingCTCFFRETRNA polymerase II
4 related topics

Structure

Electron microscopyEuchromatinHeterochromatin
3 related topics

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Nucleosome spacing

Dynamics

Modulating nucleosome structure

Nucleosome assembly in vitro

Nucleosome assembly in vivo

Gallery

  • PDB Protein Data Bank

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nucleosome

Nodes83
Edges82
Triples158
Avg. degree1.98
Density0.024096
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Nucleosome

Top relations

related to ATP-dependent nucleosome remodeling · 11
Nucleosome → At, ATP-dependent, DNA, H2A, H2A/H2B, Recently, Remodeling, Studies, Swr1, What, While
related to External links · 11
Nucleosome → Database, Eukaryotic Genome, Individual Nucleosomes Across, MBInfo, NCBI, NucleosomesNucleosome, PDBDynamic Remodeling, Response, Richmond Lab, Transcriptional PerturbationNucPosDB, What
related to H3 and H4 · 11
Nucleosome → Asf1, CAF-1, DNA, H3, H4, Histones H3, It, Newly, RCAF, The, They
related to Histone variants · 11
Nucleosome → Also, Although, CENPA, DNA, H2A, H2AX, H2AZ, H2B, H3, H4, This
related to Dynamic nucleosome remodelling across the Yeast genome · 10
Nucleosome → About, After, DNA, HMGB, However, In, Most, Saccharomyces, Studies, The
related to H2A and H2B · 10
Nucleosome → ATP-dependent, Chd1, H2A, H2B, H3, H4, In, Isw1 Ino80, NAP-1, The
related to DNA site exposure · 9
Nucleosome → DNA, DNA-binding, FRET, II, In, Introducing, Nucleosomal DNA, RNA, This
related to Gallery · 8
Nucleosome → DNA, H2A, H2B, H3, H4, Histones, PDB, The
related to Histone post-translational modifications · 8
Nucleosome → Common, DNA, Later, Modifications, Recently, Since, Some, The
related to Disulfide crosslinked nucleosome core particles · 7
Nucleosome → DNA, H2A, H2A/H2B, H3 N-terminal, N38C, The DNA-histone, Two

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dna nucleosomes histone chromatin histones h3 core h4 structure h2a proteins h2b octamer transcription two binding also particle around modifications

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nucleosomeis abasic structural unit of DNA packaging in eukaryotes0.90text
Nucleosomeis afundamental subunit of chromatin0.90text
Nucleosomeis acore particle0.90text
Nucleosomeis avery stable protein-DNA complex0.90text
H1instance ofGenome-wide nucleosome positioning maps are now available for many model organisms and human cells.Linker histones0.80text
its isoforms are involved in chromatin compactioninstance ofGenome-wide nucleosome positioning maps are now available for many model organisms and human cells.Linker histones0.80text
sit at the base of the nucleosome near the DNA entryinstance ofGenome-wide nucleosome positioning maps are now available for many model organisms and human cells.Linker histones0.80text
exit binding to the linker region of the DNAinstance ofGenome-wide nucleosome positioning maps are now available for many model organisms and human cells.Linker histones0.80text
DNA replicationinstance ofIn order to achieve the high level of control required to co-ordinate nuclear processes0.80text
repairinstance ofIn order to achieve the high level of control required to co-ordinate nuclear processes0.80text
and transcriptioninstance ofIn order to achieve the high level of control required to co-ordinate nuclear processes0.80text
cells have developed a variety of means to locallyinstance ofIn order to achieve the high level of control required to co-ordinate nuclear processes0.80text

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.