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Notch 1

Neurogenic locus notch homolog protein 1 (Notch 1) is a protein encoded in humans by the NOTCH1 gene. Notch 1 is a single-pass transmembrane receptor.

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Aliases
NOTCH1, Notch1, 9930111A19Rik, Mis6, N1, Tan1, lin-12, AOS5, AOVD1, hN1, notch 1, notch receptor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PB5, 1TOZ, 1YYH, 2F8X, 2F8Y, 2HE0, 2VJ3, 3ETO, 3I08, 3L95, 3NBN, 3V79, 4CUD, 4CUE, 4CUF, 4D0E, 4D0F, 5FM9,…
Band
9q34.3 · 2 A3|2 18.91 cM
Bgee
ventricular zone · epithelium of colon · visceral pleura · external globus pallidus · ganglionic eminence
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)

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Map overview Semantic statistics

Notch 1

Nodes32
Edges31
Triples268
Avg. degree1.94
Density0.0625
Components1

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Notch 1

Top relations

Gene ontology · 205
Notch 1 → acrosomal vesicle, adherens junction, angiogenesis, animal organ regeneration, aortic valve morphogenesis, apical plasma membrane, apoptotic process involved in embryonic digit morphogenesis, arterial endothelial cell differentiation, astrocyte differentiation, atrioventricular node development, atrioventricular valve morphogenesis, auditory receptor cell fate commitment, axonogenesis, brain development, branching morphogenesis of an epithelial tube, calcium ion binding, cardiac atrium morphogenesis, cardiac chamber formation, cardiac epithelial to mesenchymal transition, cardiac left ventricle morphogenesis
Bgee · 19
Notch 1 → blood, conjunctival fornix, epithelium of colon, external globus pallidus, ganglionic eminence, gingival epithelium, granulocyte, hair follicle, renal corpuscle, Rostral migratory stream, skin of back, superficial temporal artery, transitional epithelium of urinary bladder, vasculature of trunk, ventricular zone, vestibular membrane of cochlear duct, vestibular sensory epithelium, visceral pleura, vulva
RNA expression pattern · 19
Notch 1 → blood, conjunctival fornix, epithelium of colon, external globus pallidus, ganglionic eminence, gingival epithelium, granulocyte, hair follicle, renal corpuscle, Rostral migratory stream, skin of back, superficial temporal artery, transitional epithelium of urinary bladder, vasculature of trunk, ventricular zone, vestibular membrane of cochlear duct, vestibular sensory epithelium, visceral pleura, vulva
Band · 2
Notch 1 → 2 A3|2 18.91 cM, 9q34.3
Chr. · 2
Notch 1 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
Notch 1 → 136,546,048 bp, 26,406,675 bp
Aliases · 1
Notch 1 → NOTCH1, Notch1, 9930111A19Rik, Mis6, N1, Tan1, lin-12, AOS5, AOVD1, hN1, notch 1, notch receptor 1
Available structures · 1
Notch 1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PB5, 1TOZ, 1YYH, 2F8X, 2F8Y, 2HE0, 2VJ3, 3ETO, 3I08, 3L95, 3NBN, 3V79, 4CUD, 4CUE, 4CUF, 4D0E, 4D0F, 5FM9,…
BioGPS · 1
Notch 1 → More reference expression data
Databases · 1
Notch 1 → NCBI: entry; OMA: entry

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Important terminology

notch1 notch receptor human bp gene protein cell development chr band signaling chromosome transmembrane external differentiation pathway embryonic cells location

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Notch 1AliasesNOTCH1, Notch1, 9930111A19Rik, Mis6, N1, Tan1, lin-12, AOS5, AOVD1, hN1, notch 1, notch receptor 11.00infobox
Notch 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PB5, 1TOZ, 1YYH, 2F8X, 2F8Y, 2HE0, 2VJ3, 3ETO, 3I08, 3L95, 3NBN, 3V79, 4CUD, 4CUE, 4CUF, 4D0E, 4D0F, 5FM9,…1.00infobox
Notch 1Band9q34.31.00infobox
Notch 1Band2 A3|2 18.91 cM1.00infobox
Notch 1Bgeeventricular zone1.00infobox
Notch 1Bgeeepithelium of colon1.00infobox
Notch 1Bgeevisceral pleura1.00infobox
Notch 1Bgeeexternal globus pallidus1.00infobox
Notch 1Bgeeganglionic eminence1.00infobox
Notch 1Bgeeblood1.00infobox
Notch 1Bgeegingival epithelium1.00infobox
Notch 1Bgeesuperficial temporal artery1.00infobox
Notch 1Bgeegranulocyte1.00infobox
Notch 1Bgeevulva1.00infobox
Notch 1Bgeehair follicle1.00infobox
Notch 1Bgeevestibular sensory epithelium1.00infobox
Notch 1Bgeevasculature of trunk1.00infobox
Notch 1BgeeRostral migratory stream1.00infobox
Notch 1Bgeetransitional epithelium of urinary bladder1.00infobox
Notch 1Bgeeconjunctival fornix1.00infobox
Notch 1Bgeerenal corpuscle1.00infobox
Notch 1Bgeeskin of back1.00infobox
Notch 1Bgeevestibular membrane of cochlear duct1.00infobox
Notch 1BioGPSMore reference expression data1.00infobox
Notch 1Chr.Chromosome 9 (human)1.00infobox
Notch 1Chr.Chromosome 2 (mouse)1.00infobox
Notch 1DatabasesNCBI: entry; OMA: entry1.00infobox
Notch 1End136,546,048 bp1.00infobox
Notch 1End26,406,675 bp1.00infobox
Notch 1EnsemblENSG000001484001.00infobox

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