Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Naloxone

Naloxone, sold under the brand name Narcan among others, is an opioid antagonist, a medication used to reverse or reduce the effects of opioids. Naloxone is commonly used to restore breathing after an opioid overdose. Effects begin within two minutes when given intravenously, five minutes when injected into a muscle, and ten minutes as a nasal spray.…

History, Community, Culture & Applications

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Naloxone. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A06AH04 (WHO) V03AB15 (WHO)
Bioavailability
2% (by mouth, 90% absorption but high first-pass metabolism) 43–54% (intranasal) 98% (intramuscular, subcutaneous)
CAS Number
465-65-6 Y
ChEBI
CHEBI:7459 N

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Pharmacology

Chemistry

History

Society and culture

Veterinary use

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Naloxone

Nodes119
Edges118
Triples136
Avg. degree1.98
Density0.016807
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Naloxone

Top relations

related to Names · 19
Naloxone → Brand, British Approved Name, December, Denominazione Comune Italiana, Dénomination Commune Française, Evzio, Japanese Accepted Name, Kloxxado, Modified, Nalone, Narcan, Narcanti, Narcotan, Prenoxad Injection, Several, Teva, The, United States Adopted Name, Zimhi
related to External links · 8
Naloxone → March, MedlinePlus, Mental Health Services Administration, Naloxone Nasal Spray, OORM, Opioid Overdose Reversal Medications, SAMHSA, Substance Abuse
Legal status · 7
Naloxone → AU: S4 (Prescription only) / S3 (Pharmacist Only Medicine), BR: Class C1 (Other controlled substances), CA: OTC, DE: § 48 AMG/§ 1 MPAV (Prescription only), In general: ℞ (Prescription only), UK: POM (Prescription only), US: OTC / Rx-only
related to Pharmacodynamics · 7
Naloxone → DOR, If, In, KOR, MOR, Naloxone's, The
related to Clonidine overdose · 6
Naloxone → As, Case, Clonidine, However, Still, The
related to history · 6
Naloxone → It, Jack Fishman, Lewenstein, Mozes, Sankyo, United States
related to Legal status and availability to law enforcement and emergency personnel · 5
Naloxone → European Union, In, Nyxoid, September, United States
related to Preventing recreational opioid use · 5
Naloxone → However, If, SAMHSA's, Suboxone, This
related to Chemistry · 4
Naloxone → N-allylnoroxymorphone, Opioid, Oxymorphone, The
related to Community access · 4
Naloxone → December, In, The, US

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

opioid overdose opioids use used minutes drug administration nasal effects people states emergency us also may spray doses prescription available

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Naloxone3D model (JSmol)Interactive image1.00infobox
NaloxoneAHFS/Drugs.comMonograph1.00infobox
NaloxoneATC codeA06AH04 (WHO) V03AB15 (WHO)1.00infobox
NaloxoneBioavailability2% (by mouth, 90% absorption but high first-pass metabolism) 43–54% (intranasal) 98% (intramuscular, subcutaneous)1.00infobox
NaloxoneCAS Number465-65-6 Y1.00infobox
NaloxoneChEBICHEBI:7459 N1.00infobox
NaloxoneChEMBLChEMBL80 Y1.00infobox
NaloxoneChemSpider4447644 Y1.00infobox
NaloxoneCompTox Dashboard (EPA)DTXSID80233491.00infobox
NaloxoneDrug classOpioid antagonist1.00infobox
NaloxoneDrugBankDB01183 Y1.00infobox
NaloxoneDuration of actionINTooltip Intranasal: 30–90 min IVTooltip Intravenous: 45 min IMTooltip Intramuscular: 30–120 min1.00infobox
NaloxoneECHA InfoCard100.006.6971.00infobox
NaloxoneElimination half-life1–1.5 h1.00infobox
NaloxoneExcretionUrine, bile1.00infobox
NaloxoneFormulaC19H21NO41.00infobox
NaloxoneIUPHAR/BPS16381.00infobox
NaloxoneKEGGD08249 Y1.00infobox
NaloxoneKEGGas HCl: D01340 Y1.00infobox
NaloxoneLegal statusAU: S4 (Prescription only) / S3 (Pharmacist Only Medicine)1.00infobox
NaloxoneLegal statusBR: Class C1 (Other controlled substances)1.00infobox
NaloxoneLegal statusCA: OTC1.00infobox
NaloxoneLegal statusDE: § 48 AMG/§ 1 MPAV (Prescription only)1.00infobox
NaloxoneLegal statusUK: POM (Prescription only)1.00infobox
NaloxoneLegal statusUS: OTC / Rx-only1.00infobox
NaloxoneLegal statusIn general: ℞ (Prescription only)1.00infobox
NaloxoneLicense dataUS DailyMed: Naloxone1.00infobox
NaloxoneMedlinePlusa6120221.00infobox
NaloxoneMetabolismLiver1.00infobox
NaloxoneMolar mass327.380 g·mol−11.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.