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Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene.
The analysis highlights Meiosis, Interactions and Overview as prominent areas in the source structure around MUS81.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MUS81 shows recurring relationship patterns in the source. For example, MUS81 → 3'-flap endonuclease activity, cellular response to DNA damage stimulus, crossover junction endodeoxyribonuclease activity, DNA binding, DNA catabolic process, endonucleolytic, DNA metabolic process, DNA recombination, DNA repair, double-strand break repair via break-induced replication, endodeoxyribonuclease activity, endonuclease activity, Holliday junction resolvase complex, hydrolase activity, interstrand cross-link repair, metal ion binding, mitotic G2 DNA damage checkpoint signaling, mitotic intra-S DNA damage checkpoint signaling, nuclease activity, nucleic acid phosphodiester bond hydrolysis, nucleolus Another extracted example is MUS81 → apex of heart, body of uterus, canal of the cervix, cerebellar cortex, granulocyte, left coronary artery, left uterine tube, mucosa of transverse colon, muscle layer of sigmoid colon, muscle of thigh, otic vesicle, primary oocyte, right coronary artery, right ovary, saccule, spermatocyte, superior frontal gyrus, thymus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
recombination endonuclease bp co chromosome dna chr human band gene 11 crossover holliday meiosis pathway junction location homologous end mouse
TTTA extracted 108 structured relationships around MUS81. Examples in this analysis include MUS81 → Aliases → MUS81, SLX3, MUS81 structure-specific endonuclease subunit and MUS81 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2MC3, 4P0P, 4P0Q, 4P0R, 4P0S. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MUS81 | Aliases | MUS81, SLX3, MUS81 structure-specific endonuclease subunit | 1.00 | infobox |
| MUS81 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2MC3, 4P0P, 4P0Q, 4P0R, 4P0S | 1.00 | infobox |
| MUS81 | Band | 11q13.1 | 1.00 | infobox |
| MUS81 | Band | 19|19 A | 1.00 | infobox |
| MUS81 | Bgee | body of uterus | 1.00 | infobox |
| MUS81 | Bgee | left uterine tube | 1.00 | infobox |
| MUS81 | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| MUS81 | Bgee | granulocyte | 1.00 | infobox |
| MUS81 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| MUS81 | Bgee | right ovary | 1.00 | infobox |
| MUS81 | Bgee | canal of the cervix | 1.00 | infobox |
| MUS81 | Bgee | right coronary artery | 1.00 | infobox |
| MUS81 | Bgee | apex of heart | 1.00 | infobox |
| MUS81 | Bgee | left coronary artery | 1.00 | infobox |
| MUS81 | Bgee | muscle of thigh | 1.00 | infobox |
| MUS81 | Bgee | primary oocyte | 1.00 | infobox |
| MUS81 | Bgee | cerebellar cortex | 1.00 | infobox |
| MUS81 | Bgee | otic vesicle | 1.00 | infobox |
| MUS81 | Bgee | spermatocyte | 1.00 | infobox |
| MUS81 | Bgee | saccule | 1.00 | infobox |
| MUS81 | Bgee | thymus | 1.00 | infobox |
| MUS81 | Bgee | superior frontal gyrus | 1.00 | infobox |
| MUS81 | Bgee | ventricular zone | 1.00 | infobox |
| MUS81 | BioGPS | More reference expression data | 1.00 | infobox |
| MUS81 | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| MUS81 | Chr. | Chromosome 19 (mouse) | 1.00 | infobox |
| MUS81 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MUS81 | End | 65,867,653 bp | 1.00 | infobox |
| MUS81 | End | 5,538,430 bp | 1.00 | infobox |
| MUS81 | Ensembl | ENSG00000172732 | 1.00 | infobox |
The concept neighborhoods around MUS81 bring nearby vocabulary together. In this analysis, examples include Pathway, Search and Co. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MUS81, one of the stronger structural bridges in this analysis connects MUS81 with Meiosis. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MUS81 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Meiosis, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MUS81 · EN edition · Analysis: TopicsToTalkAbout