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Ibutamoren

Ibutamoren (INNTooltip International Nonproprietary Name; developmental code MK-677, MK-0677, LUM-201, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the…

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Effect on lean mass

GH–IGF-1 axisLean body massTotal fat massVisceral fatGrowth hormone deficiency
9 related topics

Overview

INNPotentOrally-activeSelectiveNon-peptide
15 related topics

Effect on sleep architecture

Rapid eye movement sleepSlow-wave sleep
2 related topics

Growth hormone deficiency

Height velocity
1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
CAS Number
159634-47-6 Y 159752-10-0 (mesylate)
ChEMBL
ChEMBL13817
ChemSpider
154975
CompTox Dashboard (EPA)
DTXSID90166700
DrugBank
DB18214 N

Topics to explore

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Overview

Effect on lean mass

Effect on sleep architecture

Growth hormone deficiency

Non-research use

Advanced semantic analysis

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Map overview Semantic statistics

Ibutamoren

Nodes34
Edges33
Triples42
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

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Ibutamoren

Top relations

related to Growth hormone deficiency · 8
Ibutamoren → An, In, LUM-201, OraGrowtH210, OraGrowtH212 Trials, PGHD, Phase, Topline
related to External links · 6
Ibutamoren → AdisInsightMK-677, Loungecity, Molecular Psychiatry Study, Nature, Over-Stimulation, Potential Dementia Link
related to Effect on lean mass · 5
Ibutamoren → As, GH, IGF-1, It, June
related to Non-research use · 5
Ibutamoren → However, Investigational New Drug, Since, The, United States
related to Effect on sleep architecture · 2
Ibutamoren → In, Treatment
3D model (JSmol) · 1
Ibutamoren → Interactive image
CAS Number · 1
Ibutamoren → 159634-47-6 Y 159752-10-0 (mesylate)
ChEMBL · 1
Ibutamoren → ChEMBL13817
ChemSpider · 1
Ibutamoren → 154975
CompTox Dashboard (EPA) · 1
Ibutamoren → DTXSID90166700

Important terminology Word statistics

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Important terminology

growth hormone increase levels mass shown gh igf-1 deficiency also mk-677 study sleep ghrelin name mk-0677 l-163 191 oratrope secretion

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ibutamoren3D model (JSmol)Interactive image1.00infobox
IbutamorenCAS Number159634-47-6 Y 159752-10-0 (mesylate)1.00infobox
IbutamorenChEMBLChEMBL138171.00infobox
IbutamorenChemSpider1549751.00infobox
IbutamorenCompTox Dashboard (EPA)DTXSID901667001.00infobox
IbutamorenDrugBankDB18214 N1.00infobox
IbutamorenECHA InfoCard100.236.7341.00infobox
IbutamorenElimination half-life4–6 hours (in beagles); IGF-1 levels remain elevated in humans with a single oral dose for up to 24 hours1.00infobox
IbutamorenFormulaC27H36N4O5S1.00infobox
IbutamorenIUPHAR/BPS58671.00infobox
IbutamorenLegal statusInvestigational New Drug1.00infobox
IbutamorenMolar mass528.67 g·mol−11.00infobox
IbutamorenOther namesMK-677; MK-0677; L-163,191; Oratrope1.00infobox
IbutamorenPubChem CID99390501.00infobox
IbutamorenRoutes of administrationBy mouth1.00infobox
IbutamorenUNIIGJ0EGN38UL1.00infobox

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    Min side: 3
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