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Multiple epidermal growth factor-like domains 8

Megf8 also known as Multiple Epidermal Growth Factor-like Domains 8, is a protein coding gene that encodes a single pass membrane protein, known to participate in developmental regulation and cellular communication. It is located on chromosome 19 at the 49th open reading frame in humans (19q13.2). There are two isoform constructs known for MEGF8, which…

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Aliases
MEGF8, C19orf49, CRPT2, EGFL4, SBP1, Multiple Epidermal Growth Factor-like Domains 8, multiple EGF like domains 8
Band
19q13.2 · 7|7 A3
Bgee
middle temporal gyrus · prefrontal cortex · right frontal lobe · tendon of biceps brachii · frontal pole
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Gene

Protein Architecture

Expression

  • NCBI National Center for Biotechnology Information

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Multiple epidermal growth factor-like domains 8

Nodes29
Edges28
Triples86
Avg. degree1.93
Density0.068966
Components1

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Multiple epidermal growth factor-like domains 8

Top relations

Gene ontology · 26
Multiple epidermal growth factor-like domains 8 → animal organ morphogenesis, BMP signaling pathway, calcium ion binding, cell migration involved in gastrulation, coronary vasculature development, craniofacial suture morphogenesis, determination of digestive tract left/right asymmetry, determination of heart left/right asymmetry, determination of left/right symmetry, embryonic heart tube left/right pattern formation, embryonic heart tube morphogenesis, embryonic limb morphogenesis, embryonic skeletal system morphogenesis, epiboly involved in gastrulation with mouth forming second, extracellular exosome, fasciculation of sensory neuron axon, integral component of membrane, left/right pattern formation, limb morphogenesis, membrane
Bgee · 20
Multiple epidermal growth factor-like domains 8 → ascending aorta, entorhinal cortex, epithelium of lens, external carotid artery, frontal pole, internal carotid artery, middle temporal gyrus, otic vesicle, otolith organ, parotid gland, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, Rostral migratory stream, superior frontal gyrus, supraoptic nucleus, tendon of biceps brachii, utricle, vestibular membrane of cochlear duct
RNA expression pattern · 20
Multiple epidermal growth factor-like domains 8 → ascending aorta, entorhinal cortex, epithelium of lens, external carotid artery, frontal pole, internal carotid artery, middle temporal gyrus, otic vesicle, otolith organ, parotid gland, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, Rostral migratory stream, superior frontal gyrus, supraoptic nucleus, tendon of biceps brachii, utricle, vestibular membrane of cochlear duct
Band · 2
Multiple epidermal growth factor-like domains 8 → 19q13.2, 7|7 A3
Chr. · 2
Multiple epidermal growth factor-like domains 8 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
Multiple epidermal growth factor-like domains 8 → 25,065,342 bp, 42,378,769 bp
Aliases · 1
Multiple epidermal growth factor-like domains 8 → MEGF8, C19orf49, CRPT2, EGFL4, SBP1, Multiple Epidermal Growth Factor-like Domains 8, multiple EGF like domains 8
BioGPS · 1
Multiple epidermal growth factor-like domains 8 → More reference expression data
Databases · 1
Multiple epidermal growth factor-like domains 8 → NCBI: entry; OMA: entry
Ensembl · 1
Multiple epidermal growth factor-like domains 8 → ENSG00000105429

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Important terminology

megf8 found protein domain domains predicted also gene key function several isoform amino mutations growth orthologs chromosome 19 bp human

Entity relationships Subject–Predicate–Object triples

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SubjectPredicateObjectConfidenceSrc
Multiple epidermal growth factor-like domains 8AliasesMEGF8, C19orf49, CRPT2, EGFL4, SBP1, Multiple Epidermal Growth Factor-like Domains 8, multiple EGF like domains 81.00infobox
Multiple epidermal growth factor-like domains 8Band19q13.21.00infobox
Multiple epidermal growth factor-like domains 8Band7|7 A31.00infobox
Multiple epidermal growth factor-like domains 8Bgeemiddle temporal gyrus1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeprefrontal cortex1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeright frontal lobe1.00infobox
Multiple epidermal growth factor-like domains 8Bgeetendon of biceps brachii1.00infobox
Multiple epidermal growth factor-like domains 8Bgeefrontal pole1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeprimary visual cortex1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeentorhinal cortex1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeright hemisphere of cerebellum1.00infobox
Multiple epidermal growth factor-like domains 8Bgeesuperior frontal gyrus1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeparotid gland1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeotolith organ1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeutricle1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeotic vesicle1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeinternal carotid artery1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeascending aorta1.00infobox
Multiple epidermal growth factor-like domains 8Bgeevestibular membrane of cochlear duct1.00infobox
Multiple epidermal growth factor-like domains 8BgeeRostral migratory stream1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeexternal carotid artery1.00infobox
Multiple epidermal growth factor-like domains 8Bgeeepithelium of lens1.00infobox
Multiple epidermal growth factor-like domains 8Bgeesupraoptic nucleus1.00infobox
Multiple epidermal growth factor-like domains 8BioGPSMore reference expression data1.00infobox
Multiple epidermal growth factor-like domains 8Chr.Chromosome 19 (human)1.00infobox
Multiple epidermal growth factor-like domains 8Chr.Chromosome 7 (mouse)1.00infobox
Multiple epidermal growth factor-like domains 8DatabasesNCBI: entry; OMA: entry1.00infobox
Multiple epidermal growth factor-like domains 8End42,378,769 bp1.00infobox
Multiple epidermal growth factor-like domains 8End25,065,342 bp1.00infobox
Multiple epidermal growth factor-like domains 8EnsemblENSG000001054291.00infobox

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