Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

MECR

Mitochondrial trans-2-enoyl-CoA reductase (MECR) is an enzyme that in humans is encoded by the MECR gene. It belongs to the enzyme class of oxidoreductases and catalyzes the last step of mitochondrial fatty acid synthesis (mtFAS). In doing so, MECR makes the fatty acyl chain bound to mitochondrial acyl carrier protein (mtACP) available again for…

Function, Structure & Clinical significance

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around MECR. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.3.1.104
↗
Aliases
MECR, CGI-63, FASN2B, NRBF1, mitochondrial trans-2-enoyl-CoA reductase, ETR1, nuclear receptor binding factor 1, trans-2-enoyl-CoA reductase, mitochondrial, mitochondrial 2-enoy…
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZSY, 2VCY
Band
1p35.3 · 4|4 D2.3
Bgee
apex of heart · muscle of thigh · gastrocnemius muscle · prefrontal cortex · anterior cingulate cortex
BioGPS
More reference expression data

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Reaction

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

MECR

Nodes72
Edges71
Triples107
Avg. degree1.97
Density0.027778
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

MECR

Top relations

Bgee · 20
MECR → anterior cingulate cortex, apex of heart, brown adipose tissue, C1 segment, epithelium of stomach, gastrocnemius muscle, left colon, left ventricle, lens, lip, lumbar spinal ganglion, muscle of thigh, neural layer of retina, prefrontal cortex, primary oocyte, proximal tubule, right adrenal gland, right auricle of heart, right frontal lobe, right kidney
RNA expression pattern · 20
MECR → anterior cingulate cortex, apex of heart, brown adipose tissue, C1 segment, epithelium of stomach, gastrocnemius muscle, left colon, left ventricle, lens, lip, lumbar spinal ganglion, muscle of thigh, neural layer of retina, prefrontal cortex, primary oocyte, proximal tubule, right adrenal gland, right auricle of heart, right frontal lobe, right kidney
related to Function · 15
MECR → C16, C2, C8, CoA, Condensation, In, It, Longer-chain, LYRM, NADK2, NADPH, Octanoyl-mtACP, PPAR, The MECR, Through
Gene ontology · 10
MECR → cytoplasm, fatty acid beta-oxidation, fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolism, mitochondrial matrix, mitochondrion, nucleus, oxidoreductase activity, trans-2-enoyl-CoA reductase (NADPH) activity
related to Structure · 7
MECR → C16, C4, CoA, N-terminal, The, The MECR, Through
related to Clinical significance · 4
MECR → LHON-like, MEPAN, MRI, Pathogenic
Band · 2
MECR → 1p35.3, 4|4 D2.3
Chr. · 2
MECR → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
MECR → 131,595,097 bp, 29,230,942 bp
1.3.1.104 · 1
MECR → ↗

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mitochondrial gene bp fatty chr human band enzyme trans-2-enoyl-coa reductase chromosome acid mtfas nuclear chain species protein available location synthesis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MECR1.3.1.104↗1.00infobox
MECRAliasesMECR, CGI-63, FASN2B, NRBF1, mitochondrial trans-2-enoyl-CoA reductase, ETR1, nuclear receptor binding factor 1, trans-2-enoyl-CoA reductase, mitochondrial, mitochondrial 2-enoy…1.00infobox
MECRAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZSY, 2VCY1.00infobox
MECRBand1p35.31.00infobox
MECRBand4|4 D2.31.00infobox
MECRBgeeapex of heart1.00infobox
MECRBgeemuscle of thigh1.00infobox
MECRBgeegastrocnemius muscle1.00infobox
MECRBgeeprefrontal cortex1.00infobox
MECRBgeeanterior cingulate cortex1.00infobox
MECRBgeeleft ventricle1.00infobox
MECRBgeeright frontal lobe1.00infobox
MECRBgeeright auricle of heart1.00infobox
MECRBgeeC1 segment1.00infobox
MECRBgeeright adrenal gland1.00infobox
MECRBgeebrown adipose tissue1.00infobox
MECRBgeeneural layer of retina1.00infobox
MECRBgeeright kidney1.00infobox
MECRBgeelens1.00infobox
MECRBgeeproximal tubule1.00infobox
MECRBgeelip1.00infobox
MECRBgeelumbar spinal ganglion1.00infobox
MECRBgeeprimary oocyte1.00infobox
MECRBgeeepithelium of stomach1.00infobox
MECRBgeeleft colon1.00infobox
MECRBioGPSMore reference expression data1.00infobox
MECRChr.Chromosome 1 (human)1.00infobox
MECRChr.Chromosome 4 (mouse)1.00infobox
MECRDatabasesNCBI: entry; OMA: entry1.00infobox
MECREnd29,230,942 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.