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Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than…
Products, Linkage analysis & Recombination frequency
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recombination genes linkage genetic two chromosome frequency citation needed meiosis crossover alleles chromosomes markers gene lod distance different linked analysis
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Genetic linkage | is a | tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction | 0.90 | text |
| Genetic linkage | is a | most prominent exception to Gregor Mendel's Law of Independent Assortment | 0.90 | text |
| Genetic linkage | is a | centimorgan | 0.90 | text |
| microsatellites or those generating restriction fragment length polymorphisms | instance of | confirmed or assumed noncoding DNA sequences | 0.80 | text |
| Huntington disease | instance of | While linkage analysis was successfully used to identify genetic variants that contribute to rare disorders | 0.80 | text |
| it did not perform that well when applied to more common disorders such as heart disease or different forms of cancer | instance of | While linkage analysis was successfully used to identify genetic variants that contribute to rare disorders | 0.80 | text |
| template switches | instance of | The increase in recombination may be due to replication errors by the defective DNA polymerase that are themselves recombination events | 0.80 | text |
| i.e. copy choice recombination events | instance of | The increase in recombination may be due to replication errors by the defective DNA polymerase that are themselves recombination events | 0.80 | text |
| Genetic linkage | related to Recombination frequency | Recombination | 0.60 | section |
| Genetic linkage | related to Recombination frequency | In | 0.60 | section |
| Genetic linkage | related to Recombination frequency | This | 0.60 | section |
| Genetic linkage | related to Recombination frequency | Double | 0.60 | section |
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