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Mannan-binding lectin: Regions & Measurement

Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as an opsonin and via the lectin pathway.

Language: English [EN]
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Mannan-binding lectin topic overview

The analysis highlights Regions and Measurement as prominent areas in the source structure around Mannan-binding lectin.

Related topics
40
Source areas
4
Connected nodes
44
Extracted relationships
96
Concept neighborhoods
14
Bridge connections
44

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 29 topics
Overview · 4 topics
Structure · 4 topics
Clinical significance · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD, mannose binding lectin 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HUP
Band
10q21.1 · 19 C1|19 25.14 cM
Bgee
right lobe of liver · testicle · buccal mucosa cell · kidney · haematopoietic system
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Mannan-binding lectin connects Entity context

The extracted context around Mannan-binding lectin shows recurring relationship patterns in the source. For example, Mannan-binding lectin → acute-phase response, calcium ion binding, calcium-dependent protein binding, carbohydrate binding, cell surface, collagen, collagen-containing extracellular matrix, complement activation, complement activation, classical pathway, complement activation, lectin pathway, defense response to bacterium, defense response to Gram-positive bacterium, extracellular matrix, extracellular region, extracellular space, growth plate cartilage chondrocyte morphogenesis, immune system process, innate immune response, killing by host of symbiont cells, mannose binding Another extracted example is Mannan-binding lectin → atrium, buccal mucosa cell, extensor digitorum longus muscle, gallbladder, haematopoietic system, jejunum, kidney, left lobe of liver, morula, plantaris muscle, primary oocyte, right atrium, right auricle of heart, right lobe of liver, secondary oocyte, spleen, stomach, testicle, yolk sac, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Mannan-binding lectin

Top relations

Gene ontology · 28
Mannan-binding lectin → acute-phase response, calcium ion binding, calcium-dependent protein binding, carbohydrate binding, cell surface, collagen, collagen-containing extracellular matrix, complement activation, complement activation, classical pathway, complement activation, lectin pathway, defense response to bacterium, defense response to Gram-positive bacterium, extracellular matrix, extracellular region, extracellular space, growth plate cartilage chondrocyte morphogenesis, immune system process, innate immune response, killing by host of symbiont cells, mannose binding
Bgee · 20
Mannan-binding lectin → atrium, buccal mucosa cell, extensor digitorum longus muscle, gallbladder, haematopoietic system, jejunum, kidney, left lobe of liver, morula, plantaris muscle, primary oocyte, right atrium, right auricle of heart, right lobe of liver, secondary oocyte, spleen, stomach, testicle, yolk sac, zygote
RNA expression pattern · 20
Mannan-binding lectin → atrium, buccal mucosa cell, extensor digitorum longus muscle, gallbladder, haematopoietic system, jejunum, kidney, left lobe of liver, morula, plantaris muscle, primary oocyte, right atrium, right auricle of heart, right lobe of liver, secondary oocyte, spleen, stomach, testicle, yolk sac, zygote
Band · 2
Mannan-binding lectin → 10q21.1, 19 C1|19 25.14 cM
Chr. · 2
Mannan-binding lectin → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
Mannan-binding lectin → 30,217,087 bp, 52,772,784 bp
Aliases · 1
Mannan-binding lectin → MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD, mannose binding lectin 2
Available structures · 1
Mannan-binding lectin → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HUP
BioGPS · 1
Mannan-binding lectin → More reference expression data
Databases · 1
Mannan-binding lectin → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mbl lectin human also bp mbl2 protein gene chr band chromosome 10 complement pathway function activation genes polymorphisms system surface

Mannan-binding lectin relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around Mannan-binding lectin. Examples in this analysis include Mannan-binding lectin → Aliases → MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD, mannose binding lectin 2 and Mannan-binding lectin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HUP. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Mannan-binding lectinAliasesMBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD, mannose binding lectin 21.00infobox
Mannan-binding lectinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HUP1.00infobox
Mannan-binding lectinBand10q21.11.00infobox
Mannan-binding lectinBand19 C1|19 25.14 cM1.00infobox
Mannan-binding lectinBgeeright lobe of liver1.00infobox
Mannan-binding lectinBgeetesticle1.00infobox
Mannan-binding lectinBgeebuccal mucosa cell1.00infobox
Mannan-binding lectinBgeekidney1.00infobox
Mannan-binding lectinBgeehaematopoietic system1.00infobox
Mannan-binding lectinBgeeatrium1.00infobox
Mannan-binding lectinBgeeright atrium1.00infobox
Mannan-binding lectinBgeespleen1.00infobox
Mannan-binding lectinBgeeright auricle of heart1.00infobox
Mannan-binding lectinBgeestomach1.00infobox
Mannan-binding lectinBgeeleft lobe of liver1.00infobox
Mannan-binding lectinBgeeprimary oocyte1.00infobox
Mannan-binding lectinBgeesecondary oocyte1.00infobox
Mannan-binding lectinBgeezygote1.00infobox
Mannan-binding lectinBgeeyolk sac1.00infobox
Mannan-binding lectinBgeegallbladder1.00infobox
Mannan-binding lectinBgeeplantaris muscle1.00infobox
Mannan-binding lectinBgeeextensor digitorum longus muscle1.00infobox
Mannan-binding lectinBgeemorula1.00infobox
Mannan-binding lectinBgeejejunum1.00infobox
Mannan-binding lectinBioGPSMore reference expression data1.00infobox
Mannan-binding lectinChr.Chromosome 10 (human)1.00infobox
Mannan-binding lectinChr.Chromosome 19 (mouse)1.00infobox
Mannan-binding lectinDatabasesNCBI: entry; OMA: entry1.00infobox
Mannan-binding lectinEnd52,772,784 bp1.00infobox
Mannan-binding lectinEnd30,217,087 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Mannan-binding lectin bring nearby vocabulary together. In this analysis, examples include Pathway, Binding and Activation. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Mannan-binding lectin
    • Pathway
    • Binding
    • Activation
    • System
    • Function
    • Complement
    • Protein
    • Innate
    • Mbp
    • Location
    • Mannose
    • Structure
  • mannan-binding lectin
    • Pathway
    • Binding
    • Activation
    • System
    • Function
    • Complement
    • Protein
    • Innate
    • Mbp
    • Location
    • Mannose
    • Structure
  • lectin
    • Pathway
    • Binding
    • Activation
    • System
    • Function
    • Complement
    • Protein
    • Innate
    • Mbp
    • Location
    • Mannose
    • Structure
  • innate immunity
    • Pathway
    • Mbp
    • Mouse
    • Opsonin
    • Protein
    • Bacterium
    • Binding
    • Cells
    • Expression
    • Lectin
    • Liver
    • Location
  • lectin pathway
    • Pathway
    • System
    • Binding
    • Complement
    • Protein
    • Activation
    • Function
    • Three
    • Innate
    • Mbp
    • Location
    • Mannose
  • the classical pathway
    • System
    • Complement
    • Protein
    • Binding
    • Activation
    • Three
    • Mouse
    • Bacterium
    • Cells
    • Expression
    • Liver
    • Location
  • the alternative pathway
    • System
    • Complement
    • Protein
    • Binding
    • Activation
    • Three
    • Mouse
    • Bacterium
    • Cells
    • Expression
    • Liver
    • Location
  • function
    • Binding
    • Cells
    • Expression
    • Location
    • Mannose
    • Structure
    • Lectin
    • Activation
    • Bp
    • Chr
    • Chromosome
    • Gene

Connections between topic areas Semantic bridges

For Mannan-binding lectin, one of the stronger structural bridges in this analysis connects Mannan-binding lectin with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Mannan-binding lectinFunction · splits 15 ⟂ 30
Mannan-binding lectinOverview · splits 40 ⟂ 5
Mannan-binding lectinStructure · splits 40 ⟂ 5
Mannan-binding lectinClinical significance · splits 41 ⟂ 4

Map overview Semantic statistics

Mannan-binding lectin

Nodes45
Edges44
Triples96
Avg. degree1.96
Density0.044444
Components1

Source & methodology

TTTA analyzes the structure around Mannan-binding lectin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Mannan-binding lectin · EN edition · Analysis: TopicsToTalkAbout

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