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Interleukin 1 receptor, type II: Function & Overview

Interleukin 1 receptor, type II (IL-1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor. IL1R2 also denotes its human gene.

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Interleukin 1 receptor, type II topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around Interleukin 1 receptor, type II.

Related topics
11
Source areas
2
Connected nodes
13
Extracted relationships
76
Related term clusters
10
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 9 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, Interleukin 1 receptor, type II, interleukin 1 receptor type 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3O4O
Band
2q11.2 · 1 B|1 18.65 cM
Bgee
corpus epididymis · mucosa of sigmoid colon · decidua · mucosa of pharynx · blood
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 1 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

For the semantics nerds

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Advanced semantic analysis

How Interleukin 1 receptor, type II connects Entity context

The extracted context around Interleukin 1 receptor, type II shows recurring relationship patterns in the source. For example, Interleukin 1 receptor, type II → blood, corpus epididymis, decidua, embryo, epithelium of nasopharynx, esophagus, gastrula, granulocyte, human penis, lip, mucosa of pharynx, mucosa of sigmoid colon, oral cavity, primary oocyte, right lung, skin of back, skin of external ear, subcutaneous adipose tissue, vulva Another extracted example is Interleukin 1 receptor, type II → cytokine-mediated signaling pathway, cytoplasm, extracellular region, immune response, integral component of membrane, interleukin-1 binding, interleukin-1 receptor activity, interleukin-1, type II, blocking receptor activity, interleukin-1-mediated signaling pathway, membrane, negative regulation of cytokine production involved in inflammatory response, negative regulation of interleukin-1-mediated signaling pathway, negative regulation of protein processing, plasma membrane, protein binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

Interleukin 1 receptor, type II

Top relations

Bgee · 19
Interleukin 1 receptor, type II → blood, corpus epididymis, decidua, embryo, epithelium of nasopharynx, esophagus, gastrula, granulocyte, human penis, lip, mucosa of pharynx, mucosa of sigmoid colon, oral cavity, primary oocyte, right lung, skin of back, skin of external ear, subcutaneous adipose tissue, vulva
RNA expression pattern · 19
Interleukin 1 receptor, type II → blood, corpus epididymis, decidua, embryo, epithelium of nasopharynx, esophagus, gastrula, granulocyte, human penis, lip, mucosa of pharynx, mucosa of sigmoid colon, oral cavity, primary oocyte, right lung, skin of back, skin of external ear, subcutaneous adipose tissue, vulva
Gene ontology · 15
Interleukin 1 receptor, type II → cytokine-mediated signaling pathway, cytoplasm, extracellular region, immune response, integral component of membrane, interleukin-1 binding, interleukin-1 receptor activity, interleukin-1, type II, blocking receptor activity, interleukin-1-mediated signaling pathway, membrane, negative regulation of cytokine production involved in inflammatory response, negative regulation of interleukin-1-mediated signaling pathway, negative regulation of protein processing, plasma membrane, protein binding
Band · 2
Interleukin 1 receptor, type II → 1 B|1 18.65 cM, 2q11.2
Chr. · 2
Interleukin 1 receptor, type II → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
Interleukin 1 receptor, type II → 102,028,544 bp, 40,164,391 bp
Aliases · 1
Interleukin 1 receptor, type II → IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, Interleukin 1 receptor, type II, interleukin 1 receptor type 2
Available structures · 1
Interleukin 1 receptor, type II → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3O4O
BioGPS · 1
Interleukin 1 receptor, type II → More reference expression data
Databases · 1
Interleukin 1 receptor, type II → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human receptor bp gene protein chr band chromosome also il1r2 interleukin type ii external location cluster mouse interleukin-1 cytokine signaling

Interleukin 1 receptor, type II relationships Subject–Predicate–Object triples

TTTA extracted 76 structured relationships around Interleukin 1 receptor, type II. Examples in this analysis include Interleukin 1 receptor, type II → Aliases → IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, Interleukin 1 receptor, type II, interleukin 1 receptor type 2 and Interleukin 1 receptor, type II → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3O4O. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Interleukin 1 receptor, type IIAliasesIL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, Interleukin 1 receptor, type II, interleukin 1 receptor type 21.00infobox
Interleukin 1 receptor, type IIAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3O4O1.00infobox
Interleukin 1 receptor, type IIBand2q11.21.00infobox
Interleukin 1 receptor, type IIBand1 B|1 18.65 cM1.00infobox
Interleukin 1 receptor, type IIBgeecorpus epididymis1.00infobox
Interleukin 1 receptor, type IIBgeemucosa of sigmoid colon1.00infobox
Interleukin 1 receptor, type IIBgeedecidua1.00infobox
Interleukin 1 receptor, type IIBgeemucosa of pharynx1.00infobox
Interleukin 1 receptor, type IIBgeeblood1.00infobox
Interleukin 1 receptor, type IIBgeeright lung1.00infobox
Interleukin 1 receptor, type IIBgeeepithelium of nasopharynx1.00infobox
Interleukin 1 receptor, type IIBgeehuman penis1.00infobox
Interleukin 1 receptor, type IIBgeeoral cavity1.00infobox
Interleukin 1 receptor, type IIBgeevulva1.00infobox
Interleukin 1 receptor, type IIBgeegastrula1.00infobox
Interleukin 1 receptor, type IIBgeegranulocyte1.00infobox
Interleukin 1 receptor, type IIBgeeskin of external ear1.00infobox
Interleukin 1 receptor, type IIBgeeesophagus1.00infobox
Interleukin 1 receptor, type IIBgeelip1.00infobox
Interleukin 1 receptor, type IIBgeeskin of back1.00infobox
Interleukin 1 receptor, type IIBgeesubcutaneous adipose tissue1.00infobox
Interleukin 1 receptor, type IIBgeeprimary oocyte1.00infobox
Interleukin 1 receptor, type IIBgeeembryo1.00infobox
Interleukin 1 receptor, type IIBioGPSMore reference expression data1.00infobox
Interleukin 1 receptor, type IIChr.Chromosome 2 (human)1.00infobox
Interleukin 1 receptor, type IIChr.Chromosome 1 (mouse)1.00infobox
Interleukin 1 receptor, type IIDatabasesNCBI: entry; OMA: entry1.00infobox
Interleukin 1 receptor, type IIEnd102,028,544 bp1.00infobox
Interleukin 1 receptor, type IIEnd40,164,391 bp1.00infobox
Interleukin 1 receptor, type IIEnsemblENSG000001155901.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Interleukin 1 receptor, type II bring nearby vocabulary together. In this analysis, examples include Interleukin, Receptor and Type. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Interleukin 1 receptor, type II
    • Interleukin
    • Receptor
    • Type
    • Cd121b
    • Differentiation
    • Chromosome
    • Cluster
    • Ii
    • Also
    • Component
    • Extracellular
    • Il1r2
  • interleukin 1 receptor, type ii
    • Ii
    • Type
    • Cd121b
    • External
    • Function
    • Search
    • Il1r2
    • Receptor
    • Differentiation
    • Interleukin
    • Location
    • Protein
  • interleukin receptor
    • Type
    • Protein
    • Receptor
    • Signaling
    • Cd121b
    • Differentiation
    • Il1r2
    • Chromosome
    • Cluster
    • Gene
    • Ii
    • Human
  • gene
    • Chromosome
    • Location
    • Human
    • Il1r2
    • Bp
    • Chr
    • End
    • External
    • Function
    • Mouse
    • Search
    • Cytokine
  • decoy receptor
    • Type
    • Protein
    • Signaling
    • Il1r2
    • Chromosome
    • Gene
    • Human
    • Binding
    • Component
    • External
    • Extracellular
    • Function
  • interleukin-1 receptor
    • Component
    • Extracellular
    • Signaling
    • Type
    • Protein
    • Il1r2
    • Chromosome
    • Gene
    • Mouse
    • Search
    • Human
    • Binding
  • interleukin 1 receptor antagonist
    • Type
    • Protein
    • Receptor
    • Signaling
    • Cd121b
    • Differentiation
    • Il1r2
    • Chromosome
    • Cluster
    • Gene
    • Ii
    • Human
  • interleukin 4
    • Receptor
    • Type
    • Cd121b
    • Differentiation
    • Cluster
    • Ii
    • Also
    • Il1r2
    • Protein
    • Human
    • Known
    • Activity

Connections between topic areas Semantic bridges

For Interleukin 1 receptor, type II, one of the stronger structural bridges in this analysis connects Interleukin 1 receptor, type II with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Interleukin 1 receptor, type II — Function · splits 4 ⟂ 10
Interleukin 1 receptor, type II — Overview · splits 11 ⟂ 3

Map overview Semantic statistics

Interleukin 1 receptor, type II

Nodes14
Edges13
Triples76
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around Interleukin 1 receptor, type II to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Interleukin 1 receptor, type II · EN edition · Analysis: TopicsToTalkAbout

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