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Chimeric RNA

Chimeric RNA, sometimes referred to as a fusion transcript, is composed of exons from two or more different genes that have the potential to encode novel proteins. These mRNAs are different from those produced by conventional splicing as they are produced by two or more gene loci.

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Overview

Review of RNA Production

RNA Splicing

Discovery of Chimeric RNA

Chimeric protein products

Characteristics of chimeric proteins

Computational tools for detecting chimeric RNA

Chimeric RNA in lower eukaryotes

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Chimeric RNA

Nodes72
Edges71
Triples65
Avg. degree1.97
Density0.027778
Components1

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Chimeric RNA

Top relations

related to Chimeric protein products · 23
Chimeric RNA → Abelson, ABL, AML, Among, BCR, BCR-ABL, Chimeric, CML, For, FUS-ERG, In, JAZF1, JJAZ1, MLL-AF6, MOZ-CBP, Notable, Numerous, One, RNA, SUZ12
related to Discovery of Chimeric RNA · 17
Chimeric RNA → Deep, DNA, FISH, JAZF1, JJAZ1, One, Originally, Recently, RNA, RNAs, RNAseq, These, These RNAseq, They, This, Using Southern, While
related to RNA Splicing · 13
Chimeric RNA → After DNA, Although, Creating, Depending, DNA, Fusion, Historically, However, Normally, RNA, The, They, This
related to Chimeric RNA in lower eukaryotes · 5
Chimeric RNA → Although, In, RNA, RNAs, This

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Important terminology

rna chimeric dna protein transcripts fusion exons proteins genes transcript splicing gene two different known data expressed sequencing transcription products

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
colorectalinstance ofFusion proteins are very tissue-specific and they are frequently associated with cancers0.80text
prostateinstance ofFusion proteins are very tissue-specific and they are frequently associated with cancers0.80text
and mesotheliomasinstance ofFusion proteins are very tissue-specific and they are frequently associated with cancers0.80text
trans-splicing of pre-mRNAsinstance ofchimeric transcripts can be generated in several ways0.80text
RNA transcription runoffinstance ofchimeric transcripts can be generated in several ways0.80text
from other errors in RNA transcription or they can also be the result of gene fusion following inter-chromosomal translocations or rearrangementsinstance ofchimeric transcripts can be generated in several ways0.80text
the ability to process longinstance ofunknown genes and unannotated splice variants of known genes.FusionAnalyser is a tool dedicated to the identification of driver fusion rearrangements in human cancer through the…0.80text
Chimeric RNArelated to Chimeric protein productsNumerous0.60section
Chimeric RNArelated to Chimeric protein productsRNA0.60section
Chimeric RNArelated to Chimeric protein productsIn0.60section
Chimeric RNArelated to Chimeric protein productsAmong0.60section
Chimeric RNArelated to Chimeric protein productsFor0.60section

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