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Integrin alpha 2

Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a transmembrane protein which in humans is encoded by the CD49b gene.

Biological functions, Clinical significance & Immune function

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Key facts & relationships

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Aliases
ITGA2, BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2, integrin subunit alpha 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AOX, 1DZI, 1V7P, 4BJ3
Band
5q11.2 · 13 D2.2|13 64.61 cM
Bgee
ventricular zone · epithelium of nasopharynx · bronchial epithelial cell · islet of Langerhans · visceral pleura
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

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Ligands

Biological functions

Immune function

Clinical significance

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Map overview Semantic statistics

Integrin alpha 2

Nodes112
Edges111
Triples162
Avg. degree1.98
Density0.017857
Components1

How this topic connects Entity context

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Integrin alpha 2

Top relations

Gene ontology · 74
Integrin alpha 2 → amyloid-beta binding, animal organ morphogenesis, axon, axon terminus, basal part of cell, blood coagulation, cell adhesion, cell adhesion mediated by integrin, cell population proliferation, cell projection, cell surface, cell-matrix adhesion, cell-substrate adhesion, cellular response to estradiol stimulus, cellular response to mechanical stimulus, cellular response to organic cyclic compound, collagen binding, collagen binding involved in cell-matrix adhesion, collagen receptor activity, collagen-activated signaling pathway
Bgee · 20
Integrin alpha 2 → blood, bronchial epithelial cell, cumulus cell, decidua, epithelium of nasopharynx, gastrula, gingival epithelium, islet of Langerhans, left lung lobe, lumbar spinal ganglion, molar, Paneth cell, seminal vesicula, skin of hip, skin of thigh, stellate reticulum, trigeminal ganglion, ventricular zone, visceral pleura, vulva
RNA expression pattern · 20
Integrin alpha 2 → blood, bronchial epithelial cell, cumulus cell, decidua, epithelium of nasopharynx, gastrula, gingival epithelium, islet of Langerhans, left lung lobe, lumbar spinal ganglion, molar, Paneth cell, seminal vesicula, skin of hip, skin of thigh, stellate reticulum, trigeminal ganglion, ventricular zone, visceral pleura, vulva
related to External links · 12
Integrin alpha 2 → CD49b, Cell Migration Gateway, CS1, Human Integrin, Human ITGA2, ITGA2, Medicine Medical Subject Headings, MeSH, National Library, PDB, PDBe-KB, UCSC Genome Browser
Band · 2
Integrin alpha 2 → 13 D2.2|13 64.61 cM, 5q11.2
Chr. · 2
Integrin alpha 2 → Chromosome 13 (mouse), Chromosome 5 (human)
End · 2
Integrin alpha 2 → 115,068,636 bp, 53,094,779 bp
Aliases · 1
Integrin alpha 2 → ITGA2, BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2, integrin subunit alpha 2
Available structures · 1
Integrin alpha 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AOX, 1DZI, 1V7P, 4BJ3
BioGPS · 1
Integrin alpha 2 → n/a

Important terminology Word statistics

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Important terminology

integrin α2β1 collagen extracellular receptor itga2 platelets cells gene adhesion cd49b cell matrix expression protein platelet blood binding signaling human

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Integrin alpha 2AliasesITGA2, BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2, integrin subunit alpha 21.00infobox
Integrin alpha 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AOX, 1DZI, 1V7P, 4BJ31.00infobox
Integrin alpha 2Band5q11.21.00infobox
Integrin alpha 2Band13 D2.2|13 64.61 cM1.00infobox
Integrin alpha 2Bgeeventricular zone1.00infobox
Integrin alpha 2Bgeeepithelium of nasopharynx1.00infobox
Integrin alpha 2Bgeebronchial epithelial cell1.00infobox
Integrin alpha 2Bgeeislet of Langerhans1.00infobox
Integrin alpha 2Bgeevisceral pleura1.00infobox
Integrin alpha 2Bgeeskin of thigh1.00infobox
Integrin alpha 2Bgeeskin of hip1.00infobox
Integrin alpha 2Bgeegingival epithelium1.00infobox
Integrin alpha 2Bgeeseminal vesicula1.00infobox
Integrin alpha 2Bgeevulva1.00infobox
Integrin alpha 2Bgeegastrula1.00infobox
Integrin alpha 2Bgeecumulus cell1.00infobox
Integrin alpha 2Bgeelumbar spinal ganglion1.00infobox
Integrin alpha 2Bgeemolar1.00infobox
Integrin alpha 2Bgeeblood1.00infobox
Integrin alpha 2Bgeetrigeminal ganglion1.00infobox
Integrin alpha 2BgeePaneth cell1.00infobox
Integrin alpha 2Bgeedecidua1.00infobox
Integrin alpha 2Bgeeleft lung lobe1.00infobox
Integrin alpha 2Bgeestellate reticulum1.00infobox
Integrin alpha 2BioGPSn/a1.00infobox
Integrin alpha 2Chr.Chromosome 5 (human)1.00infobox
Integrin alpha 2Chr.Chromosome 13 (mouse)1.00infobox
Integrin alpha 2DatabasesNCBI: entry; OMA: entry1.00infobox
Integrin alpha 2End53,094,779 bp1.00infobox
Integrin alpha 2End115,068,636 bp1.00infobox

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