IGFBP7

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IGFBP7 topic overview

The analysis highlights Regions, Function and Interactions as prominent areas in the source structure around IGFBP7.

Related topics: 15
Source areas: 4
Connected nodes: 19
Extracted relationships: 123
Concept neighborhoods: 11
Bridge connections: 19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics

Overview · 5 topics

Interactions · 4 topics

Structure · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF, insulin like growth factor binding protein 7
Band: 4q12 · 5|5 C3.3
Bgee: vena cava · renal medulla · saphenous vein · Epithelium of choroid plexus · pericardium
BioGPS: More reference expression data
Chr.: Chromosome 4 (human) · Chromosome 5 (mouse)
Databases: NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein
Gene
Insulin-like growth factors Insulin-like growth factor
IGFBPs Insulin-like growth factor-binding protein
Cell adhesion

Structure

Heparin

Function

Interactions

Interact Protein-protein interaction
Insulin-like growth factor 1
VPS24
IGF1R Insulin-like growth factor 1 receptor

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IGFBP7 connects Entity context

The extracted context around IGFBP7 shows recurring relationship patterns in the source. For example, IGFBP7 → cell adhesion, cellular response to hormone stimulus, collagen-containing extracellular matrix, embryo implantation, endoplasmic reticulum lumen, extracellular exosome, extracellular matrix, extracellular matrix structural constituent, extracellular region, extracellular space, growth factor binding, insulin-like growth factor binding, negative regulation of cell population proliferation, post-translational protein modification, protein binding, regulation of cell growth, regulation of steroid biosynthetic process, response to cortisol, response to heat, response to organic cyclic compound Another extracted example is IGFBP7 → aortic valve, ascending aorta, carotid body, Descending thoracic aorta, Epithelium of choroid plexus, epithelium of lens, mesenteric lymph nodes, pericardium, proximal tubule, renal corpuscle, renal medulla, right coronary artery, right kidney, right lung, saphenous vein, superficial temporal artery, tunica media of zone of aorta, urethra, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 21

IGFBP7 → cell adhesion, cellular response to hormone stimulus, collagen-containing extracellular matrix, embryo implantation, endoplasmic reticulum lumen, extracellular exosome, extracellular matrix, extracellular matrix structural constituent, extracellular region, extracellular space, growth factor binding, insulin-like growth factor binding, negative regulation of cell population proliferation, post-translational protein modification, protein binding, regulation of cell growth, regulation of steroid biosynthetic process, response to cortisol, response to heat, response to organic cyclic compound

Bgee · 19

IGFBP7 → aortic valve, ascending aorta, carotid body, Descending thoracic aorta, Epithelium of choroid plexus, epithelium of lens, mesenteric lymph nodes, pericardium, proximal tubule, renal corpuscle, renal medulla, right coronary artery, right kidney, right lung, saphenous vein, superficial temporal artery, tunica media of zone of aorta, urethra, vena cava

RNA expression pattern · 19

related to Learning and memory · 13

IGFBP7 → Alzheimer's, Blocking IGFBP7, DNA, Elevation, European Neuroscience Institute-Goettingen, Germany, IGF2, IGF2/IGFBP7, PTSD, Targeting IGFBP7, The, These, This

related to Structure · 12

IGFBP7 → Arginine, At, Glu-38, Glycine, Heparin, IGF-1, In, Phenylalanine, Structural, The, This, This Valine

related to Types · 11

IGFBP7 → ADAR, ADAR1, ADAR3, ADARs, ECS, Editing Complentary Sequence, Inosines, It, RNA, The, There

related to Interactions · 4

IGFBP7 → IGF-1, IGF1R, Insulin-like, VPS24

is a · 3

IGFBP7 → critical regulator of memory consolidation and might be used as biomarker for Alzheimer's disease, substrate for ADAR1 based on the expression spectrum of the editing enzyme, substrate for ADAR1 based on the expression spectrum of the editing enzyme.SitesThe pre-mRNA of this protein is edited at two positions

Band · 2

IGFBP7 → 4q12, 5|5 C3.3

Chr. · 2

IGFBP7 → Chromosome 4 (human), Chromosome 5 (mouse)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

editing protein growth binding bp rna human position sites region chr band site gene acid heparin insulin-like function regulation amino

IGFBP7 relationships Subject–Predicate–Object triples

TTTA extracted 123 structured relationships around IGFBP7. Examples in this analysis include IGFBP7 → Aliases → IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF, insulin like growth factor binding protein 7 and IGFBP7 → Band → 4q12. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
IGFBP7	Aliases	IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF, insulin like growth factor binding protein 7	1.00	infobox
IGFBP7	Band	4q12	1.00	infobox
IGFBP7	Band	5\|5 C3.3	1.00	infobox
IGFBP7	Bgee	vena cava	1.00	infobox
IGFBP7	Bgee	renal medulla	1.00	infobox
IGFBP7	Bgee	saphenous vein	1.00	infobox
IGFBP7	Bgee	Epithelium of choroid plexus	1.00	infobox
IGFBP7	Bgee	pericardium	1.00	infobox
IGFBP7	Bgee	superficial temporal artery	1.00	infobox
IGFBP7	Bgee	Descending thoracic aorta	1.00	infobox
IGFBP7	Bgee	right coronary artery	1.00	infobox
IGFBP7	Bgee	urethra	1.00	infobox
IGFBP7	Bgee	ascending aorta	1.00	infobox
IGFBP7	Bgee	aortic valve	1.00	infobox
IGFBP7	Bgee	epithelium of lens	1.00	infobox
IGFBP7	Bgee	right kidney	1.00	infobox
IGFBP7	Bgee	tunica media of zone of aorta	1.00	infobox
IGFBP7	Bgee	proximal tubule	1.00	infobox
IGFBP7	Bgee	renal corpuscle	1.00	infobox
IGFBP7	Bgee	carotid body	1.00	infobox
IGFBP7	Bgee	right lung	1.00	infobox
IGFBP7	Bgee	mesenteric lymph nodes	1.00	infobox
IGFBP7	BioGPS	More reference expression data	1.00	infobox
IGFBP7	Chr.	Chromosome 4 (human)	1.00	infobox
IGFBP7	Chr.	Chromosome 5 (mouse)	1.00	infobox
IGFBP7	Databases	NCBI: entry; OMA: entry	1.00	infobox
IGFBP7	End	57,110,385 bp	1.00	infobox
IGFBP7	End	77,555,888 bp	1.00	infobox
IGFBP7	Ensembl	ENSG00000163453	1.00	infobox
IGFBP7	Entrez	3490	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IGFBP7 bring nearby vocabulary together. In this analysis, examples include Alzheimer's, Memory and Factor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

IGFBP7
- Alzheimer's
- Memory
- Factor
- Found
- Function
- Gene
- Insulin-like
- Location
- Protein
- Chromosome
- Regulation
- Chr
igfbp7
- Alzheimer's
- Memory
- Factor
- Found
- Function
- Gene
- Insulin-like
- Location
- Protein
- Chromosome
- Regulation
- Chr
protein
- Regulation
- Cell
- Heparin
- Acid
- Rna
- Adhesion
- Location
- Chromosome
- Factor
- Chr
- Edited
- Human
gene
- Location
- Chromosome
- Chr
- Human
- Bp
- Band
- Factor
- Function
- Growth
- Insulin-like
- Regulation
- Protein
insulin-like growth factors
- Factor
- Insulin-like
- Regulation
- Protein
- Binding
- Function
- Gene
- Igfbp7
- Sites
- Location
- Cell
- Chromosome
cell adhesion
- Cell
- Also
- Heparin
- Regulation
- Protein
- Binding
- Growth
- Location
- Band
- Chromosome
- Factor
- Found
insulin-like growth factor 1
- Factor
- Growth
- Insulin-like
- Regulation
- Protein
- Location
- Sites
- Binding
- Chromosome
- Function
- Gene
- Chr
function
- Regulation
- Location
- Binding
- Chromosome
- Factor
- Gene
- Growth
- Insulin-like
- Chr
- Human
- Memory
- Bp

Connections between topic areas Semantic bridges

For IGFBP7, one of the stronger structural bridges in this analysis connects IGFBP7 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

IGFBP7 — Overview · splits 14 ⟂ 6

IGFBP7 — Function · splits 14 ⟂ 6

IGFBP7 — Interactions · splits 15 ⟂ 5

Map overview Semantic statistics

IGFBP7

Nodes20

Edges19

Triples123

Avg. degree1.9

Density0.1

Components1

Source & methodology

TTTA analyzes the structure around IGFBP7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IGFBP7 · EN edition · Analysis: TopicsToTalkAbout