Infliximab

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Infliximab topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Infliximab.

Related topics: 86
Source areas: 6
Connected nodes: 92
Extracted relationships: 75
Related term clusters: 26
Bridge connections: 92

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 23 topics

Adverse effects · 19 topics

Medical uses · 18 topics

Pharmacology · 13 topics

Society and culture · 9 topics

History · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AHFS/Drugs.com: Monograph
ATC code: L04AB02 (WHO)
Bioavailability: 92% (IV, if 8% left in the syringe)
Biosimilars: infliximab-abda, infliximab-axxq, infliximab-dyyb, infliximab-qbtx, Avsola, Flixabi, Inflectra, Ixifi, Remsima, Renflexis, Zessly, Zymfentra
CAS Number: 170277-31-3 Y
ChEMBL: ChEMBL1201581 N

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Infliximab

9Autoimmune diseases · Crohn's disease · Ulcerative colitis

5Chimeric antibody · Immunoglobulin G · Monoclonal antibody

6Acute infusion reaction · Chimeric protein · Biopharmaceutical

6Golimumab · Adalimumab · Certolizumab pegol

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Medical uses

Adverse effects

Pharmacology

History

Society and culture

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Infliximab connects Entity context

The extracted context around Infliximab shows recurring relationship patterns in the source. For example, Infliximab → ACT1, ACT2, Colitis Treatment, Paul Rutgeerts, Th1, Th2, The Acute, TNF, Ulcerative, William Sandborn Another extracted example is Infliximab → Centocor, George Kollias, Inc, Jan Vilček, Janssen Biotech, Junming Le, Medicine, New York University School, TNF. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Ulcerative colitis · 10

Infliximab → ACT1, ACT2, Colitis Treatment, Paul Rutgeerts, Th1, Th2, The Acute, TNF, Ulcerative, William Sandborn

related to history · 9

Infliximab → Centocor, George Kollias, Inc, Jan Vilček, Janssen Biotech, Junming Le, Medicine, New York University School, TNF

related to Psoriatic arthritis · 7

Infliximab → Among, Based, NSAID, PsA, Results, Several, TNF

related to Availability/affordability · 6

Infliximab → CDAI, Crohn's, NHS, Patients, Since February, UK

Legal status · 5

Infliximab → AU: S4 (Prescription only), CA: ℞-only / Schedule D, EU: Rx-only, UK: POM (Prescription only), US: ℞-only

has effect · 5

Infliximab → Breactivation, Enbrel, Humira, T-cell, TNF-inhibiting

related to Pharmacology · 5

Infliximab → Additionally, DNA-derived, Etanercept, IgG, TNF

is a · 2

Infliximab → chimeric monoclonal antibody biologic, most frequently used biological agent in treating relapsing polychondritis

AHFS/Drugs.com · 1

Infliximab → Monograph

ATC code · 1

Infliximab → L04AB02 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

approved disease tnf patients treatment antibody use crohn's monoclonal chimeric psoriasis mouse colitis arthritis european united states human ulcerative medical

Infliximab relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around Infliximab. Examples in this analysis include Infliximab → AHFS/Drugs.com → Monograph and Infliximab → ATC code → L04AB02 (WHO). The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Infliximab	AHFS/Drugs.com	Monograph	1.00	infobox
Infliximab	ATC code	L04AB02 (WHO)	1.00	infobox
Infliximab	Bioavailability	92% (IV, if 8% left in the syringe)	1.00	infobox
Infliximab	Biosimilars	infliximab-abda, infliximab-axxq, infliximab-dyyb, infliximab-qbtx, Avsola, Flixabi, Inflectra, Ixifi, Remsima, Renflexis, Zessly, Zymfentra	1.00	infobox
Infliximab	CAS Number	170277-31-3 Y	1.00	infobox
Infliximab	ChEMBL	ChEMBL1201581 N	1.00	infobox
Infliximab	ChemSpider	none	1.00	infobox
Infliximab	CompTox Dashboard (EPA)	DTXSID9040504	1.00	infobox
Infliximab	DrugBank	DB00065 Y	1.00	infobox
Infliximab	Elimination half-life	9.5 days	1.00	infobox
Infliximab	Formula	C6428H9912N1694O1987S46	1.00	infobox
Infliximab	KEGG	D02598 Y	1.00	infobox
Infliximab	Legal status	AU: S4 (Prescription only)	1.00	infobox
Infliximab	Legal status	CA: ℞-only / Schedule D	1.00	infobox
Infliximab	Legal status	UK: POM (Prescription only)	1.00	infobox
Infliximab	Legal status	US: ℞-only	1.00	infobox
Infliximab	Legal status	EU: Rx-only	1.00	infobox
Infliximab	License data	US DailyMed: Infliximab	1.00	infobox
Infliximab	MedlinePlus	a604023	1.00	infobox
Infliximab	Metabolism	reticuloendothelial system	1.00	infobox
Infliximab	Molar mass	144190.64 g·mol−1	1.00	infobox
Infliximab	Pregnancy category	AU: C	1.00	infobox
Infliximab	Routes of administration	Intravenous, subcutaneous	1.00	infobox
Infliximab	Source	Chimeric (mouse/human)	1.00	infobox
Infliximab	Target	Tumor necrosis factors (TNF)	1.00	infobox
Infliximab	Trade names	Remicade, others	1.00	infobox
Infliximab	Type	Whole antibody	1.00	infobox
Infliximab	UNII	B72HH48FLU	1.00	infobox
Infliximab	is a	chimeric monoclonal antibody biologic	0.90	text
Infliximab	is a	most frequently used biological agent in treating relapsing polychondritis	0.90	text

Related concept clusters Related term clusters

The concept neighborhoods around Infliximab bring nearby vocabulary together. In this analysis, examples include Disease, Patients and Treatment. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Infliximab
- Disease
- Patients
- Treatment
- Treated
- Antibody
- Use
- Used
- Severe
- Colitis
- Crohn's
- Tnf
- Fistulae
infliximab
- Disease
- Patients
- Treatment
- Treated
- Antibody
- Use
- Used
- Severe
- Colitis
- Crohn's
- Tnf
- Fistulae
crohn's disease
- Disease
- Arthritis
- Treatment
- Fistulae
- Inflammatory
- Severe
- Ulcerative
- Infliximab
- Psoriatic
- Used
- Patients
- Colitis
chimeric
- Antibody
- Monoclonal
- Human
- Mouse
- Remicade
- Medical
- Biosimilars
- Eu
- Fistulae
- Inflammatory
- Effects
- Psoriatic
monoclonal antibodies
- Adalimumab
- Drug
- Human
- Mouse
- Antibodies
- Monoclonal
- Tnf
- Inflammatory
- Remicade
- Etanercept
- Used
- Arthritis
antibody constant region
- Chimeric
- Mouse
- Monoclonal
- Human
- Remicade
- Medical
- Infliximab
- Tnf
- Biosimilars
- Eu
- Fistulae
- Inflammatory
ulcerative colitis
- Ulcerative
- Psoriatic
- Treated
- Arthritis
- Disease
- Crohn's
- Biosimilars
- Treatment
- Patients
- Infliximab
- Eu
- Fistulae
rheumatoid arthritis
- Psoriatic
- Psoriasis
- Crohn's
- Tnf
- Ulcerative
- Colitis
- Disease
- Biosimilars
- Eu
- Fistulae
- Inflammatory
- Remicade

Connections between topic areas Semantic bridges

For Infliximab, one of the stronger structural bridges in this analysis connects Infliximab with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Infliximab — Overview · splits 69 ⟂ 24

Infliximab — Adverse effects · splits 73 ⟂ 20

Infliximab — Medical uses · splits 74 ⟂ 19

Infliximab — Pharmacology · splits 79 ⟂ 14

Infliximab — Society and culture · splits 83 ⟂ 10

Infliximab — History · splits 88 ⟂ 5

Map overview Semantic statistics

Infliximab

Nodes93

Edges92

Triples75

Avg. degree1.98

Density0.021505

Components1

Source & methodology

TTTA analyzes the structure around Infliximab to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Infliximab · EN edition · Analysis: TopicsToTalkAbout

Infliximab: History, Community, Culture & Applications

Infliximab topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Medical uses

Adverse effects

Pharmacology

History

Society and culture

For the semantics nerds

Advanced semantic analysis

How Infliximab connects Entity context

Infliximab

Top relations

Important terminology

Important terminology

Infliximab relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

Infliximab

Source & methodology