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Infliximab: History, Community, Culture & Applications

Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, and Behçet's disease. It is given by slow injection into a vein…

Language: English [EN]
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Infliximab topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Infliximab.

Related topics
87
Source areas
6
Connected nodes
93
Extracted relationships
91
Concept neighborhoods
26
Bridge connections
93

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 23 topics
Adverse effects · 19 topics
Medical uses · 18 topics
Pharmacology · 13 topics
Society and culture · 10 topics
History · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AHFS/Drugs.com
Monograph
ATC code
L04AB02 (WHO)
Bioavailability
92% (IV, if 8% left in the syringe)
Biosimilars
infliximab-abda, infliximab-axxq, infliximab-dyyb, infliximab-qbtx, Avsola, Flixabi, Inflectra, Ixifi, Remsima, Renflexis, Zessly, Zymfentra
CAS Number
170277-31-3 Y
ChEMBL
ChEMBL1201581 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Pharmacology

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Infliximab connects Entity context

The extracted context around Infliximab shows recurring relationship patterns in the source. For example, Infliximab → ACT1, ACT2, At, Colitis Treatment, However, Paul Rutgeerts, Th1, Th2, The Acute, TNF, Ulcerative, William Sandborn Another extracted example is Infliximab → Centocor, George Kollias, Inc, Jan Vilček, Janssen Biotech, Junming Le, Medicine, New York University School, The, TNF. Use these groups to spot repeated connection types before inspecting the individual relationships.

Infliximab

Top relations

related to Ulcerative colitis · 12
Infliximab → ACT1, ACT2, At, Colitis Treatment, However, Paul Rutgeerts, Th1, Th2, The Acute, TNF, Ulcerative, William Sandborn
related to history · 10
Infliximab → Centocor, George Kollias, Inc, Jan Vilček, Janssen Biotech, Junming Le, Medicine, New York University School, The, TNF
related to Psoriatic arthritis · 10
Infliximab → Among, AS, Based, In, NSAID, PsA, Results, Several, The, TNF
related to Availability/affordability · 9
Infliximab → CDAI, Crohn's, For, In, NHS, Patients, Since February, The, UK
has effect · 6
Infliximab → Breactivation, Enbrel, Humira, Some, T-cell, TNF-inhibiting
related to Pharmacology · 6
Infliximab → Additionally, DNA-derived, Etanercept, IgG, It, TNF
Legal status · 5
Infliximab → AU: S4 (Prescription only), CA: ℞-only / Schedule D, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
is a · 3
Infliximab → chimeric monoclonal antibody biologic, most frequently used biological agent in treating relapsing polychondritis, therapeutic alternative on the World Health Organization's List of Essential Medicines..mw-parser-output .toclimit-2 .toclevel-1 ul
related to External links · 3
Infliximab → Media, Wikimedia Commons, Wiktionary-logo-en-v2
related to Other · 2
Infliximab → Behçet's, It

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

approved disease tnf patients treatment antibody use crohn's monoclonal chimeric psoriasis mouse colitis arthritis european united states human ulcerative medical

Infliximab relationships Subject–Predicate–Object triples

TTTA extracted 91 structured relationships around Infliximab. Examples in this analysis include Infliximab → AHFS/Drugs.com → Monograph and Infliximab → ATC code → L04AB02 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
InfliximabAHFS/Drugs.comMonograph1.00infobox
InfliximabATC codeL04AB02 (WHO)1.00infobox
InfliximabBioavailability92% (IV, if 8% left in the syringe)1.00infobox
InfliximabBiosimilarsinfliximab-abda, infliximab-axxq, infliximab-dyyb, infliximab-qbtx, Avsola, Flixabi, Inflectra, Ixifi, Remsima, Renflexis, Zessly, Zymfentra1.00infobox
InfliximabCAS Number170277-31-3 Y1.00infobox
InfliximabChEMBLChEMBL1201581 N1.00infobox
InfliximabChemSpidernone1.00infobox
InfliximabCompTox Dashboard (EPA)DTXSID90405041.00infobox
InfliximabDrugBankDB00065 Y1.00infobox
InfliximabElimination half-life9.5 days1.00infobox
InfliximabFormulaC6428H9912N1694O1987S461.00infobox
InfliximabKEGGD02598 Y1.00infobox
InfliximabLegal statusAU: S4 (Prescription only)1.00infobox
InfliximabLegal statusCA: ℞-only / Schedule D1.00infobox
InfliximabLegal statusUK: POM (Prescription only)1.00infobox
InfliximabLegal statusUS: ℞-only1.00infobox
InfliximabLegal statusEU: Rx-only1.00infobox
InfliximabLicense dataUS DailyMed: Infliximab1.00infobox
InfliximabMedlinePlusa6040231.00infobox
InfliximabMetabolismreticuloendothelial system1.00infobox
InfliximabMolar mass144190.64 g·mol−11.00infobox
InfliximabPregnancy categoryAU: C1.00infobox
InfliximabRoutes of administrationIntravenous, subcutaneous1.00infobox
InfliximabSourceChimeric (mouse/human)1.00infobox
InfliximabTargetTumor necrosis factors (TNF)1.00infobox
InfliximabTrade namesRemicade, others1.00infobox
InfliximabTypeWhole antibody1.00infobox
InfliximabUNIIB72HH48FLU1.00infobox
Infliximabis achimeric monoclonal antibody biologic0.90text
Infliximabis atherapeutic alternative on the World Health Organization's List of Essential Medicines..mw-parser-output .toclimit-2 .toclevel-1 ul0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Infliximab bring nearby vocabulary together. In this analysis, examples include Disease, Patients and Treatment. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Infliximab
    • Disease
    • Patients
    • Treatment
    • Treated
    • Antibody
    • Use
    • Used
    • Severe
    • Colitis
    • Crohn's
    • Tnf
    • Fistulae
  • infliximab
    • Disease
    • Patients
    • Treatment
    • Treated
    • Antibody
    • Use
    • Used
    • Severe
    • Colitis
    • Crohn's
    • Tnf
    • Fistulae
  • crohn's disease
    • Disease
    • Arthritis
    • Treatment
    • Fistulae
    • Inflammatory
    • Severe
    • Ulcerative
    • Infliximab
    • Psoriatic
    • Used
    • Patients
    • Colitis
  • chimeric
    • Antibody
    • Monoclonal
    • Human
    • Mouse
    • Remicade
    • Medical
    • Biosimilars
    • Eu
    • Fistulae
    • Inflammatory
    • Effects
    • Psoriatic
  • monoclonal antibodies
    • Adalimumab
    • Drug
    • Human
    • Mouse
    • Antibodies
    • Monoclonal
    • Tnf
    • Inflammatory
    • Remicade
    • Etanercept
    • Used
    • Arthritis
  • antibody constant region
    • Chimeric
    • Mouse
    • Monoclonal
    • Human
    • Remicade
    • Medical
    • Infliximab
    • Tnf
    • Biosimilars
    • Eu
    • Fistulae
    • Inflammatory
  • ulcerative colitis
    • Ulcerative
    • Psoriatic
    • Treated
    • Arthritis
    • Disease
    • Crohn's
    • Biosimilars
    • Treatment
    • Patients
    • Infliximab
    • Eu
    • Fistulae
  • rheumatoid arthritis
    • Psoriatic
    • Psoriasis
    • Crohn's
    • Tnf
    • Ulcerative
    • Colitis
    • Disease
    • Biosimilars
    • Eu
    • Fistulae
    • Inflammatory
    • Remicade

Connections between topic areas Semantic bridges

For Infliximab, one of the stronger structural bridges in this analysis connects Infliximab with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Infliximab — Overview · splits 70 ⟂ 24
Infliximab — Adverse effects · splits 74 ⟂ 20
Infliximab — Medical uses · splits 75 ⟂ 19
Infliximab — Pharmacology · splits 80 ⟂ 14
Infliximab — Society and culture · splits 83 ⟂ 11
Infliximab — History · splits 89 ⟂ 5

Map overview Semantic statistics

Infliximab

Nodes94
Edges93
Triples91
Avg. degree1.98
Density0.021277
Components1

Source & methodology

TTTA analyzes the structure around Infliximab to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Infliximab · EN edition · Analysis: TopicsToTalkAbout

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