DYNC1H1

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Explore the main themes, entities and connections around DYNC1H1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Clinical relevance

Axonal transport Neurodegenerative disease Charcot-Marie-Tooth Spinal muscular atrophy with lower extremity predominance 1 Amyotrophic lateral sclerosis

5 related topics

Interactions

Interact Protein complex PAFAH1B1 CDC5L

4 related topics

Overview

Protein Gene Dynein Motor protein

4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: DYNC1H1, DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22, CMT2O, dynein cytoplasmic 1 heavy chain 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BOR, 2BOT
Band: 14q32.31 · 12 F1|12 60.7 cM
Bgee: ganglionic eminence · ventricular zone · prefrontal cortex · stromal cell of endometrium · right frontal lobe
BioGPS: More reference expression data
Chr.: Chromosome 14 (human) · Chromosome 12 (mouse)

Topics to explore

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Overview

Interactions

Interact Protein-protein interaction
Protein complex
PAFAH1B1
CDC5L

Clinical relevance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes17

Edges16

Triples141

Avg. degree1.88

Density0.117647

Components1

How this topic connects Entity context

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DYNC1H1

Top relations

Gene ontology · 52

DYNC1H1 → antigen processing and presentation of exogenous peptide antigen via MHC class II, ATP binding, ATPase activity, axon cytoplasm, azurophil granule lumen, cell cortex, cell cycle, cell division, centrosome, ciliary basal body-plasma membrane docking, cytoplasm, cytoplasmic dynein complex, cytoplasmic microtubule, cytoplasmic microtubule organization, cytoskeletal motor activity, cytoskeleton, cytosol, dynein complex, dynein intermediate chain binding, dynein light chain binding

Bgee · 19

DYNC1H1 → Brodmann area 9, C1 segment, CA3 field, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, external carotid artery, facial motor nucleus, ganglionic eminence, lateral nuclear group of thalamus, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, stromal cell of endometrium, superior frontal gyrus, ventricular zone

RNA expression pattern · 19

related to Clinical relevance · 19

DYNC1H1 → Amyotrophic, Another, As, Autosomal, Charcot-Marie-Tooth, Defects, Due, DYNC1H1-related, DYNC1H1-Related Disorders, Given, In, It, Mutations, Prior, Recent, September, SMA-LED1, The, These

related to Interactions · 6

DYNC1H1 → CDC5L, Dynactin, MDa, Other, PAFAH1B1, The

related to Society and Culture · 3

DYNC1H1 → DYNC1H1-related, The, The DYNC1H1 Association

Band · 2

DYNC1H1 → 12 F1|12 60.7 cM, 14q32.31

Chr. · 2

DYNC1H1 → Chromosome 12 (mouse), Chromosome 14 (human)

End · 2

DYNC1H1 → 102,056,443 bp, 110,633,379 bp

Aliases · 1

DYNC1H1 → DYNC1H1, DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22, CMT2O, dynein cytoplasmic 1 heavy chain 1

Important terminology Word statistics

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Important terminology

dynein gene bp cytoplasmic chain chromosome heavy chr human band protein disorders 14 cell dync1h1-related transport external motor location symptoms

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
DYNC1H1	Aliases	DYNC1H1, DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22, CMT2O, dynein cytoplasmic 1 heavy chain 1	1.00	infobox
DYNC1H1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BOR, 2BOT	1.00	infobox
DYNC1H1	Band	14q32.31	1.00	infobox
DYNC1H1	Band	12 F1\|12 60.7 cM	1.00	infobox
DYNC1H1	Bgee	ganglionic eminence	1.00	infobox
DYNC1H1	Bgee	ventricular zone	1.00	infobox
DYNC1H1	Bgee	prefrontal cortex	1.00	infobox
DYNC1H1	Bgee	stromal cell of endometrium	1.00	infobox
DYNC1H1	Bgee	right frontal lobe	1.00	infobox
DYNC1H1	Bgee	right hemisphere of cerebellum	1.00	infobox
DYNC1H1	Bgee	Brodmann area 9	1.00	infobox
DYNC1H1	Bgee	postcentral gyrus	1.00	infobox
DYNC1H1	Bgee	lateral nuclear group of thalamus	1.00	infobox
DYNC1H1	Bgee	C1 segment	1.00	infobox
DYNC1H1	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
DYNC1H1	Bgee	primary visual cortex	1.00	infobox
DYNC1H1	Bgee	CA3 field	1.00	infobox
DYNC1H1	Bgee	entorhinal cortex	1.00	infobox
DYNC1H1	Bgee	superior frontal gyrus	1.00	infobox
DYNC1H1	Bgee	perirhinal cortex	1.00	infobox
DYNC1H1	Bgee	external carotid artery	1.00	infobox
DYNC1H1	Bgee	central gray substance of midbrain	1.00	infobox
DYNC1H1	Bgee	facial motor nucleus	1.00	infobox
DYNC1H1	BioGPS	More reference expression data	1.00	infobox
DYNC1H1	Chr.	Chromosome 14 (human)	1.00	infobox
DYNC1H1	Chr.	Chromosome 12 (mouse)	1.00	infobox
DYNC1H1	Databases	NCBI: entry; OMA: entry	1.00	infobox
DYNC1H1	End	102,056,443 bp	1.00	infobox
DYNC1H1	End	110,633,379 bp	1.00	infobox
DYNC1H1	Ensembl	ENSG00000197102	1.00	infobox

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