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Iloprost

Iloprost, sold under the brand name Ventavis among others, is a medication used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon, frostbite, and other conditions in which the blood vessels are constricted and blood cannot flow to the tissues. Iloprost is a prostacyclin mimetic.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AC11 (WHO)
Bioavailability
Not determined
CAS Number
78919-13-8 Y 73873-87-7
ChEMBL
ChEMBL236025 Y

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Overview

Medical uses

Pharmacology

Side effects

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Map overview Semantic statistics

Iloprost

Nodes36
Edges35
Triples50
Avg. degree1.94
Density0.055556
Components1

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Iloprost

Top relations

related to Pharmacology · 11
Iloprost → Activation, E2, EP1, EP2, EP3, EP4, It, PGI2, PGI2's, The, While Iloprost
related to Medical uses · 8
Iloprost → EU, III, In, New York Heart Association, NYHA Class, PAH, US, WHO Group
Legal status · 3
Iloprost → EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
has effect · 3
Iloprost → In, Serious, Ventavis
is a · 2
Iloprost → analog of PGI2 that activates PGI2's receptor, prostacyclin mimetic.For pulmonary arterial hypertension
3D model (JSmol) · 1
Iloprost → Interactive image
AHFS/Drugs.com · 1
Iloprost → Monograph
ATC code · 1
Iloprost → B01AC11 (WHO)
Bioavailability · 1
Iloprost → Not determined
CAS Number · 1
Iloprost → 78919-13-8 Y 73873-87-7

Important terminology Word statistics

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Important terminology

pulmonary hypertension arterial us blood vessels prostacyclin ventavis flow vasodilation kidney inhalation name via frostbite treatment heart failure events treat

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Iloprost3D model (JSmol)Interactive image1.00infobox
IloprostAHFS/Drugs.comMonograph1.00infobox
IloprostATC codeB01AC11 (WHO)1.00infobox
IloprostBioavailabilityNot determined1.00infobox
IloprostCAS Number78919-13-8 Y 73873-87-71.00infobox
IloprostChEMBLChEMBL236025 Y1.00infobox
IloprostChemSpider4470703 N1.00infobox
IloprostCompTox Dashboard (EPA)DTXSID20410461.00infobox
IloprostDrugBankDB01088 Y1.00infobox
IloprostECHA InfoCard100.163.8871.00infobox
IloprostElimination half-life20–30 minutes1.00infobox
IloprostExcretionKidney (68%) and fecal (12%)1.00infobox
IloprostFormulaC22H32O41.00infobox
IloprostKEGGD02721 Y1.00infobox
IloprostLegal statusUS: ℞-only1.00infobox
IloprostLegal statusEU: Rx-only1.00infobox
IloprostLegal statusIn general: ℞ (Prescription only)1.00infobox
IloprostLicense dataUS DailyMed: Iloprost1.00infobox
IloprostMedlinePlusa6120321.00infobox
IloprostMetabolismVia β-oxidation to inactive tetranor-iloprost1.00infobox
IloprostMolar mass360.494 g·mol−11.00infobox
IloprostProtein binding60%1.00infobox
IloprostPubChem CID53111811.00infobox
IloprostRoutes of administrationInhalation, intravenous1.00infobox
IloprostTrade namesVentavis, Ilomedine, Aurlumyn1.00infobox
IloprostUNIIJED5K35YGL1.00infobox
Iloprostis aprostacyclin mimetic.For pulmonary arterial hypertension0.90text
Iloprostis aanalog of PGI2 that activates PGI2's receptor0.90text

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