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Interleukin-7 receptor-α

Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene.

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Aliases
IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP1
Band
5p13.2 · 15 A1|15 4.16 cM
Bgee
right lung · granulocyte · lymph node · lower lobe of lung · epithelium of nasopharynx
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 15 (mouse)

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Interleukin-7 receptor-α

Nodes8
Edges7
Triples88
Avg. degree1.75
Density0.25
Components1

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Interleukin-7 receptor-α

Top relations

Gene ontology · 29
Interleukin-7 receptor-α → antigen binding, B cell proliferation, cell morphogenesis, cell surface receptor signaling pathway, clathrin-coated vesicle membrane, cytokine receptor activity, external side of plasma membrane, extracellular region, homeostasis of number of cells, immune response, immunoglobulin production, integral component of membrane, interleukin-7 receptor activity, interleukin-7-mediated signaling pathway, lymph node development, membrane, membrane organization, negative regulation of T cell apoptotic process, negative regulation of T cell mediated cytotoxicity, plasma membrane
Bgee · 18
Interleukin-7 receptor-α → appendix, blood, bone marrow, epithelium of nasopharynx, gallbladder, granulocyte, lower lobe of lung, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, Paneth cell, pharynx, right lung, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, upper lobe of left lung
RNA expression pattern · 18
Interleukin-7 receptor-α → appendix, blood, bone marrow, epithelium of nasopharynx, gallbladder, granulocyte, lower lobe of lung, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, Paneth cell, pharynx, right lung, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, upper lobe of left lung
Band · 2
Interleukin-7 receptor-α → 15 A1|15 4.16 cM, 5p13.2
Chr. · 2
Interleukin-7 receptor-α → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2
Interleukin-7 receptor-α → 35,879,603 bp, 9,530,262 bp
Aliases · 1
Interleukin-7 receptor-α → IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor
Available structures · 1
Interleukin-7 receptor-α → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP1
BioGPS · 1
Interleukin-7 receptor-α → More reference expression data
Databases · 1
Interleukin-7 receptor-α → NCBI: entry; OMA: entry

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Important terminology

human interleukin-7 receptor bp chr band gene il7r subunit chromosome protein external mouse location pdb uniprot alpha il7r-α available cd127

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Interleukin-7 receptor-αAliasesIL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor1.00infobox
Interleukin-7 receptor-αAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP11.00infobox
Interleukin-7 receptor-αBand5p13.21.00infobox
Interleukin-7 receptor-αBand15 A1|15 4.16 cM1.00infobox
Interleukin-7 receptor-αBgeeright lung1.00infobox
Interleukin-7 receptor-αBgeegranulocyte1.00infobox
Interleukin-7 receptor-αBgeelymph node1.00infobox
Interleukin-7 receptor-αBgeelower lobe of lung1.00infobox
Interleukin-7 receptor-αBgeeepithelium of nasopharynx1.00infobox
Interleukin-7 receptor-αBgeeappendix1.00infobox
Interleukin-7 receptor-αBgeeblood1.00infobox
Interleukin-7 receptor-αBgeethymus1.00infobox
Interleukin-7 receptor-αBgeeupper lobe of left lung1.00infobox
Interleukin-7 receptor-αBgeegallbladder1.00infobox
Interleukin-7 receptor-αBgeemesenteric lymph nodes1.00infobox
Interleukin-7 receptor-αBgeespleen1.00infobox
Interleukin-7 receptor-αBgeetibiofemoral joint1.00infobox
Interleukin-7 receptor-αBgeesubcutaneous adipose tissue1.00infobox
Interleukin-7 receptor-αBgeebone marrow1.00infobox
Interleukin-7 receptor-αBgeePaneth cell1.00infobox
Interleukin-7 receptor-αBgeepharynx1.00infobox
Interleukin-7 receptor-αBgeelumbar subsegment of spinal cord1.00infobox
Interleukin-7 receptor-αBioGPSMore reference expression data1.00infobox
Interleukin-7 receptor-αChr.Chromosome 5 (human)1.00infobox
Interleukin-7 receptor-αChr.Chromosome 15 (mouse)1.00infobox
Interleukin-7 receptor-αDatabasesNCBI: entry; OMA: entry1.00infobox
Interleukin-7 receptor-αEnd35,879,603 bp1.00infobox
Interleukin-7 receptor-αEnd9,530,262 bp1.00infobox
Interleukin-7 receptor-αEnsemblENSG000001686851.00infobox
Interleukin-7 receptor-αEntrez35751.00infobox

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