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Ibutamoren: Applications & Research

Ibutamoren (INNTooltip International Nonproprietary Name; developmental code MK-677, MK-0677, LUM-201, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the…

Language: English [EN]
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Ibutamoren topic overview

The analysis highlights Applications and Research as prominent areas in the source structure around Ibutamoren.

Related topics
27
Source areas
4
Connected nodes
32
Extracted relationships
29
Related term clusters
27
Bridge connections
32

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 15 topics
Effect on lean mass · 9 topics
Effect on sleep architecture · 2 topics
Non-research use · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
CAS Number
159634-47-6 Y 159752-10-0 (mesylate)
ChEMBL
ChEMBL13817
ChemSpider
154975
CompTox Dashboard (EPA)
DTXSID90166700
DrugBank
DB18214 N

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Effect on lean mass

Effect on sleep architecture

Non-research use

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Ibutamoren connects Entity context

The extracted context around Ibutamoren shows recurring relationship patterns in the source. For example, Ibutamoren → LUM-201, OraGrowtH210, OraGrowtH212 Trials, PGHD, Phase, Topline Another extracted example is Ibutamoren → GH, IGF-1, June. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ibutamoren

Top relations

related to Growth hormone deficiency · 6
Ibutamoren → LUM-201, OraGrowtH210, OraGrowtH212 Trials, PGHD, Phase, Topline
related to Effect on lean mass · 3
Ibutamoren → GH, IGF-1, June
related to Non-research use · 3
Ibutamoren → Investigational New Drug, Since, United States
3D model (JSmol) · 1
Ibutamoren → Interactive image
CAS Number · 1
Ibutamoren → 159634-47-6 Y 159752-10-0 (mesylate)
ChEMBL · 1
Ibutamoren → ChEMBL13817
ChemSpider · 1
Ibutamoren → 154975
CompTox Dashboard (EPA) · 1
Ibutamoren → DTXSID90166700
DrugBank · 1
Ibutamoren → DB18214 N
ECHA InfoCard · 1
Ibutamoren → 100.236.734

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

growth hormone increase levels mass shown gh igf-1 deficiency also mk-677 study sleep ghrelin name mk-0677 l-163 191 oratrope secretion

Ibutamoren relationships Subject–Predicate–Object triples

TTTA extracted 29 structured relationships around Ibutamoren. Examples in this analysis include Ibutamoren → 3D model (JSmol) → Interactive image and Ibutamoren → CAS Number → 159634-47-6 Y 159752-10-0 (mesylate). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ibutamoren3D model (JSmol)Interactive image1.00infobox
IbutamorenCAS Number159634-47-6 Y 159752-10-0 (mesylate)1.00infobox
IbutamorenChEMBLChEMBL138171.00infobox
IbutamorenChemSpider1549751.00infobox
IbutamorenCompTox Dashboard (EPA)DTXSID901667001.00infobox
IbutamorenDrugBankDB18214 N1.00infobox
IbutamorenECHA InfoCard100.236.7341.00infobox
IbutamorenElimination half-life4–6 hours (in beagles); IGF-1 levels remain elevated in humans with a single oral dose for up to 24 hours1.00infobox
IbutamorenFormulaC27H36N4O5S1.00infobox
IbutamorenIUPHAR/BPS58671.00infobox
IbutamorenLegal statusInvestigational New Drug1.00infobox
IbutamorenMolar mass528.67 g·mol−11.00infobox
IbutamorenOther namesMK-677; MK-0677; L-163,191; Oratrope1.00infobox
IbutamorenPubChem CID99390501.00infobox
IbutamorenRoutes of administrationBy mouth1.00infobox
IbutamorenUNIIGJ0EGN38UL1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Ibutamoren bring nearby vocabulary together. In this analysis, examples include Hormone, Growth and Study. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ibutamoren
    • Hormone
    • Growth
    • Study
    • Mk-677
    • Sleep
    • Deficiency
    • Increase
    • Drug
    • Ghrelin
    • Humans
    • Investigational
    • L-163
  • ibutamoren
    • Hormone
    • Growth
    • Study
    • Mk-677
    • Sleep
    • Deficiency
    • Increase
    • Drug
    • Ghrelin
    • Humans
    • Investigational
    • L-163
  • growth hormone secretagogue
    • Hormone
    • Deficiency
    • Levels
    • Mk-677
    • Ibutamoren
    • Gh
    • Shown
    • Children
    • Increase
    • L-163
    • Mass
    • Mk-0677
  • growth hormone
    • Hormone
    • Deficiency
    • Levels
    • Mk-677
    • Ibutamoren
    • Gh
    • Shown
    • Children
    • Increase
    • L-163
    • Mass
    • Mk-0677
  • hormone
    • Deficiency
    • Mk-677
    • Ibutamoren
    • Levels
    • Children
    • L-163
    • Mass
    • Mk-0677
    • Name
    • Oratrope
    • Potential
    • Gh
  • insulin-like growth factor 1
    • Hormone
    • Deficiency
    • Levels
    • Gh
    • Mk-677
    • Ibutamoren
    • Shown
    • Increase
    • Children
    • Hormones
    • Igf-1
    • L-163
  • gh–igf-1 axis
    • Secretion
    • Also
    • Igf-1
    • L-163
    • Mk-0677
    • Name
    • Oratrope
    • Cortisol
    • Lean
    • Levels
    • Mk-677
    • Shown
  • growth hormone deficiency
    • Hormone
    • Deficiency
    • Levels
    • Growth
    • Children
    • Mass
    • Mk-677
    • Ibutamoren
    • Gh
    • Shown
    • Increase
    • L-163

Connections between topic areas Semantic bridges

For Ibutamoren, one of the stronger structural bridges in this analysis connects Ibutamoren with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Ibutamoren — Overview · splits 17 ⟂ 16
Ibutamoren — Effect on lean mass · splits 23 ⟂ 10
Ibutamoren — Effect on sleep architecture · splits 30 ⟂ 3

Map overview Semantic statistics

Ibutamoren

Nodes33
Edges32
Triples29
Avg. degree1.94
Density0.060606
Components1

Source & methodology

TTTA analyzes the structure around Ibutamoren to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ibutamoren · EN edition · Analysis: TopicsToTalkAbout

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