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Isosorbide dinitrate

Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent angina pectoris. It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine. It is taken by mouth or under the tongue.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C01DA08 (WHO) C05AE02 (WHO)
Bioavailability
10–90%, average 25%
CAS Number
87-33-2 Y
ChEBI
CHEBI:6061 Y

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Side effects

Mechanism of action

Society and culture

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Map overview Semantic statistics

Isosorbide dinitrate

Nodes30
Edges29
Triples58
Avg. degree1.93
Density0.066667
Components1

How this topic connects Entity context

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Isosorbide dinitrate

Top relations

related to Society and culture · 13
Isosorbide dinitrate → Argentina, BiDil, Dilatrate-SR, FDA Orange Book, Hong Kong, Isoket, Isordil, Isosorbide, It, Schwarz, United Kingdom, US, Valeant
related to Tolerance · 8
Isosorbide dinitrate → After, II, Impaired, Neurohormonal, NO, NO-related, The, These
related to Mechanism of action · 4
Isosorbide dinitrate → NO, Similar, The, This
related to Medical uses · 3
Isosorbide dinitrate → It, Long-acting, The
3D model (JSmol) · 1
Isosorbide dinitrate → Interactive image
AHFS/Drugs.com · 1
Isosorbide dinitrate → Monograph
ATC code · 1
Isosorbide dinitrate → C01DA08 (WHO) C05AE02 (WHO)
Bioavailability · 1
Isosorbide dinitrate → 10–90%, average 25%
CAS Number · 1
Isosorbide dinitrate → 87-33-2 Y
ChEBI · 1
Isosorbide dinitrate → CHEBI:6061 Y

Important terminology Word statistics

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Important terminology

isosorbide dinitrate include medication side effects used heart failure tolerance nitrate together blood pregnancy mouth release esophageal spasms angina useful

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Isosorbide dinitrate3D model (JSmol)Interactive image1.00infobox
Isosorbide dinitrateAHFS/Drugs.comMonograph1.00infobox
Isosorbide dinitrateATC codeC01DA08 (WHO) C05AE02 (WHO)1.00infobox
Isosorbide dinitrateBioavailability10–90%, average 25%1.00infobox
Isosorbide dinitrateCAS Number87-33-2 Y1.00infobox
Isosorbide dinitrateChEBICHEBI:6061 Y1.00infobox
Isosorbide dinitrateChEMBLChEMBL2171310 N1.00infobox
Isosorbide dinitrateChemSpider6619 Y1.00infobox
Isosorbide dinitrateCompTox Dashboard (EPA)DTXSID00458321.00infobox
Isosorbide dinitrateDrugBankDB00883 Y1.00infobox
Isosorbide dinitrateECHA InfoCard100.001.5831.00infobox
Isosorbide dinitrateElimination half-life1 hour1.00infobox
Isosorbide dinitrateExcretionKidney1.00infobox
Isosorbide dinitrateFormulaC6H8N2O81.00infobox
Isosorbide dinitrateKEGGD00516 Y1.00infobox
Isosorbide dinitrateLegal statusIn general: ℞ (Prescription only)1.00infobox
Isosorbide dinitrateLicense dataUS DailyMed: Isosorbide dinitrate1.00infobox
Isosorbide dinitrateMedlinePlusa6823481.00infobox
Isosorbide dinitrateMetabolismLiver1.00infobox
Isosorbide dinitrateMolar mass236.136 g·mol−11.00infobox
Isosorbide dinitrateOther namesISDN; (3R,3aS,6S,6aS)-hexahydrofuro[3,2-b]furan-3,6-diyl dinitrate1.00infobox
Isosorbide dinitratePregnancy categoryAU: B11.00infobox
Isosorbide dinitratePubChem CID68831.00infobox
Isosorbide dinitrateRoutes of administrationBy mouth1.00infobox
Isosorbide dinitrateTrade namesIsordil, others1.00infobox
Isosorbide dinitrateUNIIIA7306519N1.00infobox
Isosorbide dinitrateis amedication used for heart failure0.90text

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