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The hypothalamic–pituitary–gonadal axis (HPG axis, also known as the hypothalamic–pituitary–testicular/ovarian axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual endocrine glands were a single entity. Because these glands often act in concert, physiologists and endocrinologists find it convenient and descriptive…
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gnrh axis lh fsh estrogen hypothalamus hpg secretion levels also pituitary hormone neurons development function testosterone cells feedback hormones cycle
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| follicle development | instance of | regulating processes | 0.80 | text |
| oocyte maturation | instance of | regulating processes | 0.80 | text |
| and ovulation | instance of | regulating processes | 0.80 | text |
| neuropeptide Y | instance of | leptin influences GnRH neuronal activity indirectly via regulation of downstream mediators | 0.80 | text |
| α-melanocyte-stimulating hormone | instance of | leptin influences GnRH neuronal activity indirectly via regulation of downstream mediators | 0.80 | text |
| and agouti-related peptide | instance of | leptin influences GnRH neuronal activity indirectly via regulation of downstream mediators | 0.80 | text |
| obesity | instance of | particularly in the face of metabolic challenges | 0.80 | text |
| endothelin-1 | instance of | Luteolysis involves factors | 0.80 | text |
| TNFα | instance of | Luteolysis involves factors | 0.80 | text |
| which inhibit steroidogenesis | instance of | Luteolysis involves factors | 0.80 | text |
| induce apoptosis | instance of | Luteolysis involves factors | 0.80 | text |
| overtraining commonly seen in elite athletes | instance of | due to metabolic or stress-related factors | 0.80 | text |
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