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Heat shock 10 kDa protein 1 (Hsp10), also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF), is a protein that in humans is encoded by the HSPE1 gene. The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL.
The analysis highlights Structure and function, Clinical utility and Detection as prominent areas in the source structure around GroES.
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Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around GroES shows recurring relationship patterns in the source. For example, GroES → abdominal wall, blastocyst, C1 segment, embryo, epiblast, human kidney, hypothalamus, left adrenal cortex, left adrenal gland, migratory enteric neural crest cell, mucosa of transverse colon, neural tube, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, ventricular zone, yolk sac Another extracted example is GroES → activation of cysteine-type endopeptidase activity involved in apoptotic process, ATP binding, chaperone binding, chaperone cofactor-dependent protein refolding, cytoplasm, extracellular exosome, membrane, metal ion binding, mitochondrial matrix, mitochondrion, osteoblast differentiation, protein binding, protein folding, response to unfolded protein, RNA binding, unfolded protein binding. Use these groups to spot repeated connection types before inspecting the individual relationships.
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epf pregnancy groel protein human bp chr band fertilization also gene chromosome marker chaperonin hspe1 binding may within embryos test
TTTA extracted 90 structured relationships around GroES. Examples in this analysis include GroES → Aliases → HSPE1, heat shock 10kDa protein 1, CPN10, EPF, GROES, HSP10, heat shock protein family E (Hsp10) member 1 and GroES → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4PJ1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| GroES | Aliases | HSPE1, heat shock 10kDa protein 1, CPN10, EPF, GROES, HSP10, heat shock protein family E (Hsp10) member 1 | 1.00 | infobox |
| GroES | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4PJ1 | 1.00 | infobox |
| GroES | Band | 2q33.1 | 1.00 | infobox |
| GroES | Band | 1|1 C1.2 | 1.00 | infobox |
| GroES | Bgee | right adrenal gland | 1.00 | infobox |
| GroES | Bgee | right adrenal cortex | 1.00 | infobox |
| GroES | Bgee | left adrenal gland | 1.00 | infobox |
| GroES | Bgee | left adrenal cortex | 1.00 | infobox |
| GroES | Bgee | mucosa of transverse colon | 1.00 | infobox |
| GroES | Bgee | right lobe of liver | 1.00 | infobox |
| GroES | Bgee | hypothalamus | 1.00 | infobox |
| GroES | Bgee | human kidney | 1.00 | infobox |
| GroES | Bgee | ventricular zone | 1.00 | infobox |
| GroES | Bgee | C1 segment | 1.00 | infobox |
| GroES | Bgee | embryo | 1.00 | infobox |
| GroES | Bgee | yolk sac | 1.00 | infobox |
| GroES | Bgee | right kidney | 1.00 | infobox |
| GroES | Bgee | epiblast | 1.00 | infobox |
| GroES | Bgee | blastocyst | 1.00 | infobox |
| GroES | Bgee | abdominal wall | 1.00 | infobox |
| GroES | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| GroES | Bgee | neural tube | 1.00 | infobox |
| GroES | BioGPS | More reference expression data | 1.00 | infobox |
| GroES | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| GroES | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| GroES | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| GroES | End | 197,503,449 bp | 1.00 | infobox |
| GroES | End | 55,130,466 bp | 1.00 | infobox |
| GroES | Ensembl | ENSG00000115541 | 1.00 | infobox |
| GroES | Entrez | 3336 | 1.00 | infobox |
The concept neighborhoods around GroES bring nearby vocabulary together. In this analysis, examples include Protein, Atp and Subunits. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For GroES, one of the stronger structural bridges in this analysis connects GroES with Structure and function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around GroES to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure and function, Clinical utility & Detection, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — GroES · EN edition · Analysis: TopicsToTalkAbout
