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GRB10

Growth factor receptor-bound protein 10 also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene.

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Interactions

7 related topics

Function

5 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
GRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 10
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV
Band
7p12.1 · 11 A1|11 7.15 cM
Bgee
body of pancreas · pars compacta · visceral pleura · Brodmann area 23 · pars reticulata
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 11 (mouse)

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Overview

Function

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Map overview Semantic statistics

GRB10

Nodes18
Edges17
Triples98
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

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GRB10

Top relations

Bgee · 20
GRB10 → abdominal wall, atrioventricular valve, atrium, body of pancreas, Brodmann area 23, dermis, dorsal motor nucleus of vagus nerve, endocardial cushion, endothelial cell, Epithelium of choroid plexus, Gonadal ridge, mandibular prominence, maxillary prominence, middle temporal gyrus, pancreatic ductal cell, pars compacta, pars reticulata, primitive streak, ureter, visceral pleura
Gene ontology · 20
GRB10 → axon guidance, cytoplasm, cytosol, identical protein binding, insulin receptor binding, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, negative regulation of Wnt signaling pathway, plasma membrane, positive regulation of cold-induced thermogenesis, positive regulation of phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein binding, protein-containing complex, response to insulin, signal transduction
RNA expression pattern · 20
GRB10 → abdominal wall, atrioventricular valve, atrium, body of pancreas, Brodmann area 23, dermis, dorsal motor nucleus of vagus nerve, endocardial cushion, endothelial cell, Epithelium of choroid plexus, Gonadal ridge, mandibular prominence, maxillary prominence, middle temporal gyrus, pancreatic ductal cell, pars compacta, pars reticulata, primitive streak, ureter, visceral pleura
related to External links · 7
GRB10 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, Protein, This, United States National Library
related to Interactions · 7
GRB10 → Abl, BCR, C-Raf, Insulin, Insulin-like, Kit, MAP2K1
Band · 2
GRB10 → 11 A1|11 7.15 cM, 7p12.1
Chr. · 2
GRB10 → Chromosome 11 (mouse), Chromosome 7 (human)
End · 2
GRB10 → 11,988,683 bp, 50,793,462 bp
Aliases · 1
GRB10 → GRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 10
Available structures · 1
GRB10 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV

Important terminology Word statistics

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Important terminology

gene bp protein growth chr human band factor chromosome insulin receptor location mouse insulin-like 10 grb-ir function external known receptor-binding

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GRB10AliasesGRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 101.00infobox
GRB10Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV1.00infobox
GRB10Band7p12.11.00infobox
GRB10Band11 A1|11 7.15 cM1.00infobox
GRB10Bgeebody of pancreas1.00infobox
GRB10Bgeepars compacta1.00infobox
GRB10Bgeevisceral pleura1.00infobox
GRB10BgeeBrodmann area 231.00infobox
GRB10Bgeepars reticulata1.00infobox
GRB10Bgeeendothelial cell1.00infobox
GRB10Bgeedorsal motor nucleus of vagus nerve1.00infobox
GRB10Bgeemiddle temporal gyrus1.00infobox
GRB10Bgeepancreatic ductal cell1.00infobox
GRB10BgeeEpithelium of choroid plexus1.00infobox
GRB10Bgeemandibular prominence1.00infobox
GRB10Bgeeendocardial cushion1.00infobox
GRB10Bgeeatrium1.00infobox
GRB10Bgeemaxillary prominence1.00infobox
GRB10Bgeeatrioventricular valve1.00infobox
GRB10BgeeGonadal ridge1.00infobox
GRB10Bgeeabdominal wall1.00infobox
GRB10Bgeeureter1.00infobox
GRB10Bgeeprimitive streak1.00infobox
GRB10Bgeedermis1.00infobox
GRB10BioGPSMore reference expression data1.00infobox
GRB10Chr.Chromosome 7 (human)1.00infobox
GRB10Chr.Chromosome 11 (mouse)1.00infobox
GRB10DatabasesNCBI: entry; OMA: entry1.00infobox
GRB10End50,793,462 bp1.00infobox
GRB10End11,988,683 bp1.00infobox

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