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GRB10: Interactions, Function & Overview

Growth factor receptor-bound protein 10 also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene.

Language: English [EN]
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GRB10 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around GRB10.

Related topics
14
Source areas
3
Connected nodes
17
Extracted relationships
98
Concept neighborhoods
10
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Function · 5 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 10
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV
Band
7p12.1 · 11 A1|11 7.15 cM
Bgee
body of pancreas · pars compacta · visceral pleura · Brodmann area 23 · pars reticulata
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GRB10 connects Entity context

The extracted context around GRB10 shows recurring relationship patterns in the source. For example, GRB10 → abdominal wall, atrioventricular valve, atrium, body of pancreas, Brodmann area 23, dermis, dorsal motor nucleus of vagus nerve, endocardial cushion, endothelial cell, Epithelium of choroid plexus, Gonadal ridge, mandibular prominence, maxillary prominence, middle temporal gyrus, pancreatic ductal cell, pars compacta, pars reticulata, primitive streak, ureter, visceral pleura Another extracted example is GRB10 → axon guidance, cytoplasm, cytosol, identical protein binding, insulin receptor binding, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, negative regulation of Wnt signaling pathway, plasma membrane, positive regulation of cold-induced thermogenesis, positive regulation of phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein binding, protein-containing complex, response to insulin, signal transduction. Use these groups to spot repeated connection types before inspecting the individual relationships.

GRB10

Top relations

Bgee · 20
GRB10 → abdominal wall, atrioventricular valve, atrium, body of pancreas, Brodmann area 23, dermis, dorsal motor nucleus of vagus nerve, endocardial cushion, endothelial cell, Epithelium of choroid plexus, Gonadal ridge, mandibular prominence, maxillary prominence, middle temporal gyrus, pancreatic ductal cell, pars compacta, pars reticulata, primitive streak, ureter, visceral pleura
Gene ontology · 20
GRB10 → axon guidance, cytoplasm, cytosol, identical protein binding, insulin receptor binding, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, negative regulation of Wnt signaling pathway, plasma membrane, positive regulation of cold-induced thermogenesis, positive regulation of phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein binding, protein-containing complex, response to insulin, signal transduction
RNA expression pattern · 20
GRB10 → abdominal wall, atrioventricular valve, atrium, body of pancreas, Brodmann area 23, dermis, dorsal motor nucleus of vagus nerve, endocardial cushion, endothelial cell, Epithelium of choroid plexus, Gonadal ridge, mandibular prominence, maxillary prominence, middle temporal gyrus, pancreatic ductal cell, pars compacta, pars reticulata, primitive streak, ureter, visceral pleura
related to External links · 7
GRB10 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, Protein, This, United States National Library
related to Interactions · 7
GRB10 → Abl, BCR, C-Raf, Insulin, Insulin-like, Kit, MAP2K1
Band · 2
GRB10 → 11 A1|11 7.15 cM, 7p12.1
Chr. · 2
GRB10 → Chromosome 11 (mouse), Chromosome 7 (human)
End · 2
GRB10 → 11,988,683 bp, 50,793,462 bp
Aliases · 1
GRB10 → GRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 10
Available structures · 1
GRB10 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp protein growth chr human band factor chromosome insulin receptor location mouse insulin-like 10 grb-ir function external known receptor-binding

GRB10 relationships Subject–Predicate–Object triples

TTTA extracted 98 structured relationships around GRB10. Examples in this analysis include GRB10 → Aliases → GRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 10 and GRB10 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GRB10AliasesGRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS, growth factor receptor bound protein 101.00infobox
GRB10Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HK0, 1NRV1.00infobox
GRB10Band7p12.11.00infobox
GRB10Band11 A1|11 7.15 cM1.00infobox
GRB10Bgeebody of pancreas1.00infobox
GRB10Bgeepars compacta1.00infobox
GRB10Bgeevisceral pleura1.00infobox
GRB10BgeeBrodmann area 231.00infobox
GRB10Bgeepars reticulata1.00infobox
GRB10Bgeeendothelial cell1.00infobox
GRB10Bgeedorsal motor nucleus of vagus nerve1.00infobox
GRB10Bgeemiddle temporal gyrus1.00infobox
GRB10Bgeepancreatic ductal cell1.00infobox
GRB10BgeeEpithelium of choroid plexus1.00infobox
GRB10Bgeemandibular prominence1.00infobox
GRB10Bgeeendocardial cushion1.00infobox
GRB10Bgeeatrium1.00infobox
GRB10Bgeemaxillary prominence1.00infobox
GRB10Bgeeatrioventricular valve1.00infobox
GRB10BgeeGonadal ridge1.00infobox
GRB10Bgeeabdominal wall1.00infobox
GRB10Bgeeureter1.00infobox
GRB10Bgeeprimitive streak1.00infobox
GRB10Bgeedermis1.00infobox
GRB10BioGPSMore reference expression data1.00infobox
GRB10Chr.Chromosome 7 (human)1.00infobox
GRB10Chr.Chromosome 11 (mouse)1.00infobox
GRB10DatabasesNCBI: entry; OMA: entry1.00infobox
GRB10End50,793,462 bp1.00infobox
GRB10End11,988,683 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GRB10 bring nearby vocabulary together. In this analysis, examples include Gene, Growth and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GRB10
    • Gene
    • Growth
    • Protein
    • Receptor
    • Insulin
    • Function
    • Interact
    • Known
    • Search
    • Insulin-like
    • Location
    • Chromosome
  • grb10
    • Gene
    • Growth
    • Protein
    • Receptor
    • Insulin
    • Function
    • Interact
    • Known
    • Search
    • Insulin-like
    • Location
    • Chromosome
  • protein
    • Insulin
    • Function
    • Known
    • Receptor-binding
    • Search
    • Tyrosine
    • Insulin-like
    • Location
    • Receptor
    • Chromosome
    • Human
    • Bp
  • gene
    • Grb10
    • Growth
    • Insulin
    • Protein
    • Insulin-like
    • Location
    • Receptor
    • Chromosome
    • Human
    • Bp
    • Chr
    • A1
  • receptor tyrosine kinases
    • Interact
    • Search
    • Insulin-like
    • Location
    • Signaling
    • Human
    • A1
    • Encoded
    • End
    • Function
    • Growth
    • Isoforms
  • abl gene
    • Grb10
    • Growth
    • Insulin
    • Protein
    • Insulin-like
    • Location
    • Receptor
    • Chromosome
    • Human
    • Bp
    • Chr
    • A1
  • bcr gene
    • Grb10
    • Growth
    • Insulin
    • Protein
    • Insulin-like
    • Location
    • Receptor
    • Chromosome
    • Human
    • Bp
    • Chr
    • A1
  • function
    • Search
    • Location
    • Receptor
    • Chromosome
    • Human
    • Signaling
    • Bp
    • Chr
    • A1
    • End
    • Grb-ir
    • Grb10

Connections between topic areas Semantic bridges

For GRB10, one of the stronger structural bridges in this analysis connects GRB10 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GRB10Interactions · splits 10 ⟂ 8
GRB10Function · splits 12 ⟂ 6
GRB10Overview · splits 15 ⟂ 3

Map overview Semantic statistics

GRB10

Nodes18
Edges17
Triples98
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around GRB10 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GRB10 · EN edition · Analysis: TopicsToTalkAbout

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