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GRAP2: Interactions, Function & Overview

GRB2-related adapter protein 2 also known as GRB2-related adaptor downstream of Shc (GADS) is a 37 kDa protein that in humans is encoded by the GRAP2 gene.

Language: English [EN]
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GRAP2 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around GRAP2.

Related topics
11
Source areas
3
Connected nodes
14
Extracted relationships
76
Concept neighborhoods
8
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Overview · 3 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GRAP2, GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38, GRB2-related adaptor protein 2, GRB2 related adaptor protein 2
Band
22q13.1 · 15|15 E1
Bgee
monocyte · granulocyte · blood · thymus · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GRAP2 connects Entity context

The extracted context around GRAP2 shows recurring relationship patterns in the source. For example, GRAP2 → cell differentiation, cell migration, cell-cell signaling, cytoplasm, cytosol, endosome, extrinsic component of cytoplasmic side of plasma membrane, Fc-epsilon receptor signaling pathway, innate immune response, non-membrane spanning protein tyrosine kinase activity, nucleus, peptidyl-tyrosine autophosphorylation, positive regulation of signal transduction, protein binding, Ras protein signal transduction, regulation of cell population proliferation, signaling receptor binding, T cell costimulation, T cell receptor signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway Another extracted example is GRAP2 → appendix, blood, bone marrow cell, embryo, epithelium of colon, genital tubercle, granulocyte, lymph node, mesenteric lymph nodes, monocyte, seminiferous tubule, spleen, tail of embryo, testicle, thymus, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

GRAP2

Top relations

Gene ontology · 20
GRAP2 → cell differentiation, cell migration, cell-cell signaling, cytoplasm, cytosol, endosome, extrinsic component of cytoplasmic side of plasma membrane, Fc-epsilon receptor signaling pathway, innate immune response, non-membrane spanning protein tyrosine kinase activity, nucleus, peptidyl-tyrosine autophosphorylation, positive regulation of signal transduction, protein binding, Ras protein signal transduction, regulation of cell population proliferation, signaling receptor binding, T cell costimulation, T cell receptor signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway
Bgee · 16
GRAP2 → appendix, blood, bone marrow cell, embryo, epithelium of colon, genital tubercle, granulocyte, lymph node, mesenteric lymph nodes, monocyte, seminiferous tubule, spleen, tail of embryo, testicle, thymus, yolk sac
RNA expression pattern · 16
GRAP2 → appendix, blood, bone marrow cell, embryo, epithelium of colon, genital tubercle, granulocyte, lymph node, mesenteric lymph nodes, monocyte, seminiferous tubule, spleen, tail of embryo, testicle, thymus, yolk sac
related to Interactions · 4
GRAP2 → CCNDBP1, CD28, Linker, Lymphocyte
Band · 2
GRAP2 → 15|15 E1, 22q13.1
Chr. · 2
GRAP2 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
GRAP2 → 39,973,721 bp, 80,537,055 bp
Aliases · 1
GRAP2 → GRAP2, GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38, GRB2-related adaptor protein 2, GRB2 related adaptor protein 2
BioGPS · 1
GRAP2 → More reference expression data
Databases · 1
GRAP2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein bp gene chr human band chromosome 22 grb2-related adaptor location mouse gads function member 973 721 end 39 15

GRAP2 relationships Subject–Predicate–Object triples

TTTA extracted 76 structured relationships around GRAP2. Examples in this analysis include GRAP2 → Aliases → GRAP2, GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38, GRB2-related adaptor protein 2, GRB2 related adaptor protein 2 and GRAP2 → Band → 22q13.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GRAP2AliasesGRAP2, GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38, GRB2-related adaptor protein 2, GRB2 related adaptor protein 21.00infobox
GRAP2Band22q13.11.00infobox
GRAP2Band15|15 E11.00infobox
GRAP2Bgeemonocyte1.00infobox
GRAP2Bgeegranulocyte1.00infobox
GRAP2Bgeeblood1.00infobox
GRAP2Bgeethymus1.00infobox
GRAP2Bgeelymph node1.00infobox
GRAP2Bgeetesticle1.00infobox
GRAP2Bgeespleen1.00infobox
GRAP2Bgeeepithelium of colon1.00infobox
GRAP2Bgeeappendix1.00infobox
GRAP2Bgeebone marrow cell1.00infobox
GRAP2Bgeeyolk sac1.00infobox
GRAP2Bgeeembryo1.00infobox
GRAP2Bgeemesenteric lymph nodes1.00infobox
GRAP2Bgeegenital tubercle1.00infobox
GRAP2Bgeetail of embryo1.00infobox
GRAP2Bgeeseminiferous tubule1.00infobox
GRAP2BioGPSMore reference expression data1.00infobox
GRAP2Chr.Chromosome 22 (human)1.00infobox
GRAP2Chr.Chromosome 15 (mouse)1.00infobox
GRAP2DatabasesNCBI: entry; OMA: entry1.00infobox
GRAP2End39,973,721 bp1.00infobox
GRAP2End80,537,055 bp1.00infobox
GRAP2EnsemblENSG000001003511.00infobox
GRAP2Entrez94021.00infobox
GRAP2External IDsOMIM: 604518; MGI: 1333842; GeneCards: GRAP21.00infobox
GRAP2Gene location (Human)Gene location (Human)Chr.Chromosome 22 (human)Band22q13.1Start39,901,084 bpEnd39,973,721 bp1.00infobox
GRAP2Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 15 (mouse)Band15|15 E1Start80,456,795 bpEnd80,537,055 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GRAP2 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GRAP2
    • Gene
    • Protein
    • Function
    • Grb2
    • Grb2-related
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
    • Kda
  • grap2
    • Gene
    • Protein
    • Function
    • Grb2
    • Grb2-related
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
    • Kda
  • gene
    • Location
    • Chromosome
    • Grap2
    • Human
    • Bp
    • Chr
    • End
    • Function
    • Grb2
    • Mouse
    • Grb2-related
    • Protein
  • protein
    • Member
    • Binding
    • Domains
    • Family
    • Function
    • Grb2
    • Kinase
    • Related
    • Sh3
    • Signaling
    • Location
    • Chromosome
  • lymphocyte cytosolic protein 2
    • Member
    • Binding
    • Domains
    • Family
    • Function
    • Grb2
    • Kinase
    • Related
    • Sh3
    • Signaling
    • Location
    • Chromosome
  • function
    • Grb2
    • Location
    • Chromosome
    • Gene
    • Grap2
    • Human
    • Bp
    • Chr
    • Binding
    • End
    • Family
    • Gads
  • grb2
    • Location
    • Human
    • Binding
    • End
    • Family
    • Kinase
    • Mouse
    • Related
    • Signaling
    • Protein
    • Grb2-related
    • Member
  • kda
    • Humans
    • Known
    • Shc
    • Protein

Connections between topic areas Semantic bridges

For GRAP2, one of the stronger structural bridges in this analysis connects GRAP2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GRAP2Interactions · splits 7 ⟂ 8
GRAP2Overview · splits 11 ⟂ 4

Map overview Semantic statistics

GRAP2

Nodes15
Edges14
Triples76
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around GRAP2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GRAP2 · EN edition · Analysis: TopicsToTalkAbout

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