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GNAI3

Guanine nucleotide-binding protein G(k) subunit alpha is a protein that in humans is encoded by the GNAI3 gene. This protein is one of the 4 subunits in the Gi/o family of G-proteins. These subunits play an important role in inhibitory signaling for G protein-coupled receptors. Variants in this gene are associated with Auriculocondylar Syndrome 1, a rare…

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Aliases
GNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S
Band
1p13.3 · 3 F2.3|3 46.83 cM
Bgee
gingival epithelium · skin of thigh · parietal pleura · visceral pleura · hair follicle
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)

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GNAI3

Nodes18
Edges17
Triples118
Avg. degree1.89
Density0.111111
Components1

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GNAI3

Top relations

Gene ontology · 48
GNAI3 → adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, brain development, cell cycle, cell division, centrosome, cytoplasm, cytoskeleton, dopamine receptor signaling pathway, endoplasmic reticulum membrane, extracellular exosome, G protein-coupled receptor binding, G protein-coupled receptor signaling pathway, G protein-coupled serotonin receptor binding, G-protein beta/gamma-subunit complex binding, GDP binding, Golgi apparatus, Golgi membrane, GTP binding, GTP metabolic process
Bgee · 20
GNAI3 → abdominal wall, cartilage tissue, cervix epithelium, dermis, efferent ductule, gastrula, gingival epithelium, granulocyte, hair follicle, medial ganglionic eminence, oral cavity, parietal pleura, primitive streak, seminal vesicula, skin of external ear, skin of hip, skin of thigh, tibia, vas deferens, visceral pleura
RNA expression pattern · 20
GNAI3 → abdominal wall, cartilage tissue, cervix epithelium, dermis, efferent ductule, gastrula, gingival epithelium, granulocyte, hair follicle, medial ganglionic eminence, oral cavity, parietal pleura, primitive streak, seminal vesicula, skin of external ear, skin of hip, skin of thigh, tibia, vas deferens, visceral pleura
related to Interactions · 7
GNAI3 → RGS10RGS12, RGS14, RGS16, RGS18, RGS19, RGS5, RIC8A
Band · 2
GNAI3 → 1p13.3, 3 F2.3|3 46.83 cM
Chr. · 2
GNAI3 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
GNAI3 → 108,053,462 bp, 109,600,195 bp
Aliases · 1
GNAI3 → GNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A
Available structures · 1
GNAI3 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S
BioGPS · 1
GNAI3 → More reference expression data

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Important terminology

gene bp protein chr human band chromosome subunit alpha location subunits mouse signaling protein-coupled associated ear gi external search 600

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GNAI3AliasesGNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A1.00infobox
GNAI3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S1.00infobox
GNAI3Band1p13.31.00infobox
GNAI3Band3 F2.3|3 46.83 cM1.00infobox
GNAI3Bgeegingival epithelium1.00infobox
GNAI3Bgeeskin of thigh1.00infobox
GNAI3Bgeeparietal pleura1.00infobox
GNAI3Bgeevisceral pleura1.00infobox
GNAI3Bgeehair follicle1.00infobox
GNAI3Bgeeskin of hip1.00infobox
GNAI3Bgeetibia1.00infobox
GNAI3Bgeecartilage tissue1.00infobox
GNAI3Bgeeoral cavity1.00infobox
GNAI3Bgeecervix epithelium1.00infobox
GNAI3Bgeeabdominal wall1.00infobox
GNAI3Bgeemedial ganglionic eminence1.00infobox
GNAI3Bgeedermis1.00infobox
GNAI3Bgeeskin of external ear1.00infobox
GNAI3Bgeeprimitive streak1.00infobox
GNAI3Bgeeefferent ductule1.00infobox
GNAI3Bgeevas deferens1.00infobox
GNAI3Bgeegastrula1.00infobox
GNAI3Bgeeseminal vesicula1.00infobox
GNAI3Bgeegranulocyte1.00infobox
GNAI3BioGPSMore reference expression data1.00infobox
GNAI3Chr.Chromosome 1 (human)1.00infobox
GNAI3Chr.Chromosome 3 (mouse)1.00infobox
GNAI3DatabasesNCBI: entry; OMA: entry1.00infobox
GNAI3End109,600,195 bp1.00infobox
GNAI3End108,053,462 bp1.00infobox

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