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GNAI3: Measurement, Interactions & Overview

Guanine nucleotide-binding protein G(k) subunit alpha is a protein that in humans is encoded by the GNAI3 gene. This protein is one of the 4 subunits in the Gi/o family of G-proteins. These subunits play an important role in inhibitory signaling for G protein-coupled receptors. Variants in this gene are associated with Auriculocondylar Syndrome 1, a rare…

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GNAI3 topic overview

The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around GNAI3.

Related topics
15
Source areas
2
Connected nodes
17
Extracted relationships
118
Concept neighborhoods
6
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 10 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S
Band
1p13.3 · 3 F2.3|3 46.83 cM
Bgee
gingival epithelium · skin of thigh · parietal pleura · visceral pleura · hair follicle
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GNAI3 connects Entity context

The extracted context around GNAI3 shows recurring relationship patterns in the source. For example, GNAI3 → adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, brain development, cell cycle, cell division, centrosome, cytoplasm, cytoskeleton, dopamine receptor signaling pathway, endoplasmic reticulum membrane, extracellular exosome, G protein-coupled receptor binding, G protein-coupled receptor signaling pathway, G protein-coupled serotonin receptor binding, G-protein beta/gamma-subunit complex binding, GDP binding, Golgi apparatus, Golgi membrane, GTP binding, GTP metabolic process Another extracted example is GNAI3 → abdominal wall, cartilage tissue, cervix epithelium, dermis, efferent ductule, gastrula, gingival epithelium, granulocyte, hair follicle, medial ganglionic eminence, oral cavity, parietal pleura, primitive streak, seminal vesicula, skin of external ear, skin of hip, skin of thigh, tibia, vas deferens, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

GNAI3

Top relations

Gene ontology · 48
GNAI3 → adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, brain development, cell cycle, cell division, centrosome, cytoplasm, cytoskeleton, dopamine receptor signaling pathway, endoplasmic reticulum membrane, extracellular exosome, G protein-coupled receptor binding, G protein-coupled receptor signaling pathway, G protein-coupled serotonin receptor binding, G-protein beta/gamma-subunit complex binding, GDP binding, Golgi apparatus, Golgi membrane, GTP binding, GTP metabolic process
Bgee · 20
GNAI3 → abdominal wall, cartilage tissue, cervix epithelium, dermis, efferent ductule, gastrula, gingival epithelium, granulocyte, hair follicle, medial ganglionic eminence, oral cavity, parietal pleura, primitive streak, seminal vesicula, skin of external ear, skin of hip, skin of thigh, tibia, vas deferens, visceral pleura
RNA expression pattern · 20
GNAI3 → abdominal wall, cartilage tissue, cervix epithelium, dermis, efferent ductule, gastrula, gingival epithelium, granulocyte, hair follicle, medial ganglionic eminence, oral cavity, parietal pleura, primitive streak, seminal vesicula, skin of external ear, skin of hip, skin of thigh, tibia, vas deferens, visceral pleura
related to Interactions · 7
GNAI3 → RGS10RGS12, RGS14, RGS16, RGS18, RGS19, RGS5, RIC8A
Band · 2
GNAI3 → 1p13.3, 3 F2.3|3 46.83 cM
Chr. · 2
GNAI3 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
GNAI3 → 108,053,462 bp, 109,600,195 bp
Aliases · 1
GNAI3 → GNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A
Available structures · 1
GNAI3 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S
BioGPS · 1
GNAI3 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp protein chr human band chromosome subunit alpha location subunits mouse signaling protein-coupled associated ear gi external search 600

GNAI3 relationships Subject–Predicate–Object triples

TTTA extracted 118 structured relationships around GNAI3. Examples in this analysis include GNAI3 → Aliases → GNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A and GNAI3 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GNAI3AliasesGNAI3, 87U6, ARCND1, G protein subunit alpha i3, HG1A1.00infobox
GNAI3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IHB, 2ODE, 2V4Z, 4G5O, 4G5R, 4G5S1.00infobox
GNAI3Band1p13.31.00infobox
GNAI3Band3 F2.3|3 46.83 cM1.00infobox
GNAI3Bgeegingival epithelium1.00infobox
GNAI3Bgeeskin of thigh1.00infobox
GNAI3Bgeeparietal pleura1.00infobox
GNAI3Bgeevisceral pleura1.00infobox
GNAI3Bgeehair follicle1.00infobox
GNAI3Bgeeskin of hip1.00infobox
GNAI3Bgeetibia1.00infobox
GNAI3Bgeecartilage tissue1.00infobox
GNAI3Bgeeoral cavity1.00infobox
GNAI3Bgeecervix epithelium1.00infobox
GNAI3Bgeeabdominal wall1.00infobox
GNAI3Bgeemedial ganglionic eminence1.00infobox
GNAI3Bgeedermis1.00infobox
GNAI3Bgeeskin of external ear1.00infobox
GNAI3Bgeeprimitive streak1.00infobox
GNAI3Bgeeefferent ductule1.00infobox
GNAI3Bgeevas deferens1.00infobox
GNAI3Bgeegastrula1.00infobox
GNAI3Bgeeseminal vesicula1.00infobox
GNAI3Bgeegranulocyte1.00infobox
GNAI3BioGPSMore reference expression data1.00infobox
GNAI3Chr.Chromosome 1 (human)1.00infobox
GNAI3Chr.Chromosome 3 (mouse)1.00infobox
GNAI3DatabasesNCBI: entry; OMA: entry1.00infobox
GNAI3End109,600,195 bp1.00infobox
GNAI3End108,053,462 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GNAI3 bring nearby vocabulary together. In this analysis, examples include Protein, External and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GNAI3
    • Protein
    • External
    • Search
    • Gene
    • Location
    • Subunit
    • Chromosome
    • Human
    • Bp
    • Chr
    • Guanine
    • Humans
  • gnai3
    • Protein
    • External
    • Search
    • Gene
    • Location
    • Subunit
    • Chromosome
    • Human
    • Bp
    • Chr
    • Guanine
    • Humans
  • protein
    • External
    • Search
    • Location
    • Subunit
    • Chromosome
    • Human
    • Bp
    • Chr
    • Family
    • G-proteins
    • One
    • Associated
  • gene
    • Gnai3
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • Associated
    • Ear
    • End
    • External
    • F2
  • g protein-coupled receptors
    • Signaling
    • Role
    • Associated
    • Ear
    • End
    • External
    • F2
    • Mouse
    • Search
    • Subunits
    • Location
    • Band
  • gi/o
    • Family
    • G-proteins
    • One
    • Subunits
    • Subunit
    • Protein

Connections between topic areas Semantic bridges

For GNAI3, one of the stronger structural bridges in this analysis connects GNAI3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GNAI3 — Interactions · splits 7 ⟂ 11
GNAI3 — Overview · splits 12 ⟂ 6

Map overview Semantic statistics

GNAI3

Nodes18
Edges17
Triples118
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around GNAI3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GNAI3 · EN edition · Analysis: TopicsToTalkAbout

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