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Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes the survival of many types of neurons. It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes, i.e. it is…
The analysis highlights History and Art as prominent areas in the source structure around Glial cell line-derived neurotrophic factor.
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The extracted context around Glial cell line-derived neurotrophic factor shows recurring relationship patterns in the source. For example, Glial cell line-derived neurotrophic factor → adult locomotory behavior, axon guidance, branching involved in ureteric bud morphogenesis, chemoattractant activity involved in axon guidance, chemoattraction of axon, commissural neuron axon guidance, dorsal spinal cord development, embryonic organ development, enteric nervous system development, extracellular region, extracellular space, growth factor activity, intracellular anatomical structure, MAPK cascade, mesenchymal to epithelial transition involved in metanephros morphogenesis, metanephros development, mRNA stabilization, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of neuron apoptotic process Another extracted example is Glial cell line-derived neurotrophic factor → Bowman's capsule, deltoid muscle, epithelium of small intestine, gastric mucosa, gastrocnemius muscle, genitourinary system, Gonadal ridge, Hindgut, inner muscle layer, medullary collecting duct, migratory enteric neural crest cell, mucosa of ileum, muscle layer of sigmoid colon, muscle of thigh, muscularis mucosae, quadriceps femoris muscle, renal corpuscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, tibialis anterior muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gdnf protein gene gfrα1 receptor also cell bp ret parkinson's cells factor chr human band disease neurotrophic neurons chromosome spermatogonia
TTTA extracted 123 structured relationships around Glial cell line-derived neurotrophic factor. Examples in this analysis include Glial cell line-derived neurotrophic factor → Aliases → GDNF, ATF1, ATF2, HFB1-HSCR3, glial cell derived neurotrophic factor, ATF and Glial cell line-derived neurotrophic factor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2V5E, 3FUB, 4UX8. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Glial cell line-derived neurotrophic factor | Aliases | GDNF, ATF1, ATF2, HFB1-HSCR3, glial cell derived neurotrophic factor, ATF | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2V5E, 3FUB, 4UX8 | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Band | 5p13.2 | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Band | 15|15 A1 | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | muscle of thigh | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | tibialis anterior muscle | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | deltoid muscle | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | gastrocnemius muscle | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | quadriceps femoris muscle | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | gastric mucosa | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | mucosa of ileum | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | medullary collecting duct | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | inner muscle layer | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | muscularis mucosae | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | renal corpuscle | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | Hindgut | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | Bowman's capsule | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | epithelium of small intestine | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | genitourinary system | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Bgee | Gonadal ridge | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | BioGPS | More reference expression data | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | End | 37,840,041 bp | 1.00 | infobox |
| Glial cell line-derived neurotrophic factor | End | 7,867,056 bp | 1.00 | infobox |
The concept neighborhoods around Glial cell line-derived neurotrophic factor bring nearby vocabulary together. In this analysis, examples include Neurotrophic, Line-derived and Factor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Glial cell line-derived neurotrophic factor, one of the stronger structural bridges in this analysis connects Glial cell line-derived neurotrophic factor with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Glial cell line-derived neurotrophic factor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Glial cell line-derived neurotrophic factor · EN edition · Analysis: TopicsToTalkAbout