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Farnesyltransferase

Farnesyltransferase (EC 2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small…

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Overview

ECEnzymesPrenyltransferaseIsoprenoidFarnesyl group
29 related topics

Farnesyltransferase structure and function

SubunitsBeta subunitAlpha helicesZincCation
10 related topics

Structural studies

StructuresPDB
2 related topics

Key facts & relationships

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BRENDA
enzyme data
CAS no.
131384-38-8
EC no.
2.5.1.58
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

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Overview

Farnesyltransferase structure and function

Structural studies

Advanced semantic analysis

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Map overview Semantic statistics

Farnesyltransferase

Nodes45
Edges44
Triples31
Avg. degree1.96
Density0.044444
Components1

How this topic connects Entity context

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Farnesyltransferase

Top relations

related to Specificity · 8
Farnesyltransferase → CaaX, Cysteine, FTase, FTase's, It, Only, The, There
related to Farnesyltransferase structure and function · 6
Farnesyltransferase → All, Both, CaaX, SN2, The, This
related to overview · 3
Farnesyltransferase → Most, SH, This
BRENDA · 1
Farnesyltransferase → enzyme data
CAS no. · 1
Farnesyltransferase → 131384-38-8
EC no. · 1
Farnesyltransferase → 2.5.1.58
ExPASy · 1
Farnesyltransferase → NiceZyme view
Gene Ontology · 1
Farnesyltransferase → AmiGO / QuickGO
KEGG · 1
Farnesyltransferase → enzyme entry
MetaCyc · 1
Farnesyltransferase → metabolic pathway

Important terminology Word statistics

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Important terminology

proteins ftase farnesyl group substrates cysteine subunit protein also motif diphosphate alpha amino called caax acid inhibitors agents 58 enzyme

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FarnesyltransferaseBRENDAenzyme data1.00infobox
FarnesyltransferaseCAS no.131384-38-81.00infobox
FarnesyltransferaseEC no.2.5.1.581.00infobox
FarnesyltransferaseExPASyNiceZyme view1.00infobox
FarnesyltransferaseGene OntologyAmiGO / QuickGO1.00infobox
FarnesyltransferaseKEGGenzyme entry1.00infobox
FarnesyltransferaseMetaCycmetabolic pathway1.00infobox
FarnesyltransferaseNCBIproteins1.00infobox
FarnesyltransferasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
FarnesyltransferasePMCarticles1.00infobox
FarnesyltransferasePubMedarticles1.00infobox
FarnesyltransferaseRheareactions1.00infobox
FarnesyltransferaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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    Min side: 3
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