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The bimolecular nucleophilic substitution (SN2) is a type of reaction mechanism that is common in organic chemistry. In the SN2 reaction, a strong nucleophile forms a new bond to an sp3-hybridised carbon atom via a backside attack, all while the leaving group detaches from the reaction center in a concerted (i.e. simultaneous) fashion.
Factors affecting the rate of the reaction, Reaction mechanism & E2 competition
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reaction sn2 nucleophile leaving group substitution substrate sn1 mechanism carbon nucleophilic reactions solvent groups center via substrates good bromide strong
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| this | instance of | Reactions | 0.80 | text |
| with an alkoxide as the nucleophile | instance of | Reactions | 0.80 | text |
| are known as the Williamson ether synthesis.If the substrate that is undergoing SN2 reaction has a chiral centre | instance of | Reactions | 0.80 | text |
| then inversion of configuration | instance of | Reactions | 0.80 | text |
| SN2 reaction | related to E2 competition | SN2 | 0.60 | section |
| SN2 reaction | related to E2 competition | E2 | 0.60 | section |
| SN2 reaction | related to E2 competition | This | 0.60 | section |
| SN2 reaction | related to E2 competition | Elimination | 0.60 | section |
| SN2 reaction | related to E2 competition | With | 0.60 | section |
| SN2 reaction | related to E2 competition | As | 0.60 | section |
| SN2 reaction | related to E2 competition | Other | 0.60 | section |
| SN2 reaction | related to E2 competition | In | 0.60 | section |
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