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Fibrillarin

rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene.

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Function

15 related topics

Interactions

3 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
FBL, FIB, FLRN, RNU3IP1, fibrillarin, Nop1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IPX
Band
19q13.2 · 7|7 A3
Bgee
ganglionic eminence · left ovary · right ovary · skin of abdomen · skin of leg
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)

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Overview

Function

Interactions

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Map overview Semantic statistics

Fibrillarin

Nodes24
Edges23
Triples115
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

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Fibrillarin

Top relations

Gene ontology · 29
Fibrillarin → ATPase binding, box C/D RNA 3'-end processing, box C/D RNP complex, Cajal body, chromosome, dense fibrillar component, extracellular exosome, fibrillar center, granular component, histone glutamine methylation, histone-glutamine methyltransferase activity, membrane, methylation, methyltransferase activity, nucleolus, nucleoplasm, nucleus, osteoblast differentiation, protein binding, RNA binding
Bgee · 19
Fibrillarin → bone marrow, canal of the cervix, ectocervix, embryo, epiblast, fallopian tube, ganglionic eminence, left ovary, lens, lip, monocyte, right ovary, skin of abdomen, skin of leg, spleen, tail of embryo, thymus, ventricular zone, yolk sac
RNA expression pattern · 19
Fibrillarin → bone marrow, canal of the cervix, ectocervix, embryo, epiblast, fallopian tube, ganglionic eminence, left ovary, lens, lip, monocyte, right ovary, skin of abdomen, skin of leg, spleen, tail of embryo, thymus, ventricular zone, yolk sac
related to Function · 16
Fibrillarin → Antisera, DFC, It, Its, N-terminal, RNA, RNA-binding, RNAs, RNP, SnRNAs, SnRNP, The, This, U13, U3, U8
is a · 3
Fibrillarin → component of several ribonucleoproteins including a nucleolar small nuclear ribonucleoprotein, enzyme that in humans is encoded by the FBL gene, snoRNA methyltransferase has been reviewed
Band · 2
Fibrillarin → 19q13.2, 7|7 A3
Chr. · 2
Fibrillarin → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
Fibrillarin → 27,878,694 bp, 39,846,379 bp
related to Interactions · 2
Fibrillarin → DDX5, SMN1
Aliases · 1
Fibrillarin → FBL, FIB, FLRN, RNU3IP1, fibrillarin, Nop1

Important terminology Word statistics

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Important terminology

protein bp gene chr human chromosome band small 19 fbl nucleolar 15 5-kda component processing location function ribonucleoprotein contains domain

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FibrillarinAliasesFBL, FIB, FLRN, RNU3IP1, fibrillarin, Nop11.00infobox
FibrillarinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2IPX1.00infobox
FibrillarinBand19q13.21.00infobox
FibrillarinBand7|7 A31.00infobox
FibrillarinBgeeganglionic eminence1.00infobox
FibrillarinBgeeleft ovary1.00infobox
FibrillarinBgeeright ovary1.00infobox
FibrillarinBgeeskin of abdomen1.00infobox
FibrillarinBgeeskin of leg1.00infobox
FibrillarinBgeecanal of the cervix1.00infobox
FibrillarinBgeeventricular zone1.00infobox
FibrillarinBgeeectocervix1.00infobox
FibrillarinBgeefallopian tube1.00infobox
FibrillarinBgeemonocyte1.00infobox
FibrillarinBgeeepiblast1.00infobox
FibrillarinBgeeyolk sac1.00infobox
FibrillarinBgeebone marrow1.00infobox
FibrillarinBgeelens1.00infobox
FibrillarinBgeelip1.00infobox
FibrillarinBgeespleen1.00infobox
FibrillarinBgeethymus1.00infobox
FibrillarinBgeetail of embryo1.00infobox
FibrillarinBgeeembryo1.00infobox
FibrillarinBioGPSMore reference expression data1.00infobox
FibrillarinChr.Chromosome 19 (human)1.00infobox
FibrillarinChr.Chromosome 7 (mouse)1.00infobox
FibrillarinDatabasesNCBI: entry; OMA: entry1.00infobox
FibrillarinEnd39,846,379 bp1.00infobox
FibrillarinEnd27,878,694 bp1.00infobox
FibrillarinEnsemblENSG00000105202 ENSG000002805481.00infobox

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