FCER1A

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Explore the main themes, entities and connections around FCER1A. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Immunoglobulin E Mast cells Basophils Dendritic cells Langerhans cells

14 related topics

Gene regulation

IL-4 Transcription factors GATA-1 PU.1 YY1

6 related topics

Expression

Antigen presenting cells Antigen presentation Macrophages Neutrophils Platelets

6 related topics

Therapeutic relevance

Omalizumab Allergen immunotherapy Ligelizumab Quilizumab CD23

6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: FCER1A, FCE1A, FcERI, Fc fragment of IgE receptor Ia
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2Q, 1F6A, 1J86, 1J87, 1J88, 1J89, 1RPQ, 2Y7Q
Band: 1q23.2 · 1 H3|1 80.33 cM
Bgee: skin of thigh · skin of hip · skin of arm · granulocyte · mononuclear cell
BioGPS: More reference expression data
Chr.: Chromosome 1 (human) · Chromosome 1 (mouse)

Topics to explore

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Overview

Genetic variation

Promoter Promoter (genetics)

Gene regulation

IL-4 IL-4-inhibitor-1
Transcription factors Transcription factor
GATA-1 GATA1
PU.1 SPI1
YY1
Elf-1 ELF1

Expression

Antigen presenting cells Antigen-presenting cell
Antigen presentation
Macrophages Macrophage
Neutrophils Neutrophil
Platelets Platelet
Eosinophils Eosinophil

Structure

Function

Clinical significance

Polymorphisms Polymorphism (biology)
Pharmacogenetic Pharmacogenomics

Therapeutic relevance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes50

Edges49

Triples122

Avg. degree1.96

Density0.04

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

FCER1A

Top relations

related to Therapeutic relevance · 22

FCER1A → After, Although, As, Because FCER1A, CD23, FcεRI, IgE, IgE-FcεRI, IgE-mediated, In, Later, Ligelizumab, Many, MEDI4212, Omalizumab, Past, Quilizumab, The IgE-FcεRI, There, This

Bgee · 19

FCER1A → blood, bone marrow, carotid body, esophagus, gallbladder, granulocyte, lip, monocyte, mononuclear cell, muscle of thigh, oral cavity, skin of arm, skin of external ear, skin of hip, skin of thigh, spermatid, testicle, tunica adventitia of aorta, vulva

RNA expression pattern · 19

related to Gene regulation · 11

FCER1A → Elf-1, FCεRI, GATA-1, IgE, IL-4, In, Many, PU, The, These, YY1

Gene ontology · 7

FCER1A → cell surface, Fc-epsilon receptor signaling pathway, IgE binding, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane

related to history · 7

FCER1A → Early, FCER1A's, FcεRI, IgE, Later, One, Recent

related to Function · 6

FCER1A → Activation, FcεRI, IgE, Langerhans, The, When

related to Clinical significance · 4

FCER1A → Because FCER1A, Different FCER1A, IgE, The

related to Genetic variation · 4

FCER1A → IgE, In FCER1A, Some, The

Band · 2

FCER1A → 1 H3|1 80.33 cM, 1q23.2

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ige fcεri receptor cells allergic gene mast expression binding promoter omalizumab studies also bp regulation human immune polymorphisms basophils signaling

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
FCER1A	Aliases	FCER1A, FCE1A, FcERI, Fc fragment of IgE receptor Ia	1.00	infobox
FCER1A	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2Q, 1F6A, 1J86, 1J87, 1J88, 1J89, 1RPQ, 2Y7Q	1.00	infobox
FCER1A	Band	1q23.2	1.00	infobox
FCER1A	Band	1 H3\|1 80.33 cM	1.00	infobox
FCER1A	Bgee	skin of thigh	1.00	infobox
FCER1A	Bgee	skin of hip	1.00	infobox
FCER1A	Bgee	skin of arm	1.00	infobox
FCER1A	Bgee	granulocyte	1.00	infobox
FCER1A	Bgee	mononuclear cell	1.00	infobox
FCER1A	Bgee	monocyte	1.00	infobox
FCER1A	Bgee	oral cavity	1.00	infobox
FCER1A	Bgee	vulva	1.00	infobox
FCER1A	Bgee	testicle	1.00	infobox
FCER1A	Bgee	gallbladder	1.00	infobox
FCER1A	Bgee	tunica adventitia of aorta	1.00	infobox
FCER1A	Bgee	blood	1.00	infobox
FCER1A	Bgee	lip	1.00	infobox
FCER1A	Bgee	bone marrow	1.00	infobox
FCER1A	Bgee	skin of external ear	1.00	infobox
FCER1A	Bgee	esophagus	1.00	infobox
FCER1A	Bgee	muscle of thigh	1.00	infobox
FCER1A	Bgee	spermatid	1.00	infobox
FCER1A	Bgee	carotid body	1.00	infobox
FCER1A	BioGPS	More reference expression data	1.00	infobox
FCER1A	Chr.	Chromosome 1 (human)	1.00	infobox
FCER1A	Chr.	Chromosome 1 (mouse)	1.00	infobox
FCER1A	Databases	NCBI: entry; OMA: entry	1.00	infobox
FCER1A	End	159,308,224 bp	1.00	infobox
FCER1A	End	173,054,781 bp	1.00	infobox
FCER1A	Ensembl	ENSG00000179639	1.00	infobox

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