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FCER1A: Regions, Function & Gene regulation

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, also known as FCER1A, is a protein which in humans is encoded by the FCER1A gene.

Language: English [EN]
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FCER1A topic overview

The analysis highlights Regions, Function and Gene regulation as prominent areas in the source structure around FCER1A.

Related topics
41
Source areas
8
Connected nodes
49
Extracted relationships
122
Concept neighborhoods
19
Bridge connections
49

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 14 topics
Expression · 6 topics
Gene regulation · 6 topics
Therapeutic relevance · 6 topics
Structure · 4 topics
Clinical significance · 2 topics
Overview · 2 topics
Genetic variation · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
FCER1A, FCE1A, FcERI, Fc fragment of IgE receptor Ia
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2Q, 1F6A, 1J86, 1J87, 1J88, 1J89, 1RPQ, 2Y7Q
Band
1q23.2 · 1 H3|1 80.33 cM
Bgee
skin of thigh · skin of hip · skin of arm · granulocyte · mononuclear cell
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Genetic variation

Gene regulation

Expression

Structure

Function

Clinical significance

Therapeutic relevance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FCER1A connects Entity context

The extracted context around FCER1A shows recurring relationship patterns in the source. For example, FCER1A → After, Although, As, Because FCER1A, CD23, FcεRI, IgE, IgE-FcεRI, IgE-mediated, In, Later, Ligelizumab, Many, MEDI4212, Omalizumab, Past, Quilizumab, The IgE-FcεRI, There, This Another extracted example is FCER1A → blood, bone marrow, carotid body, esophagus, gallbladder, granulocyte, lip, monocyte, mononuclear cell, muscle of thigh, oral cavity, skin of arm, skin of external ear, skin of hip, skin of thigh, spermatid, testicle, tunica adventitia of aorta, vulva. Use these groups to spot repeated connection types before inspecting the individual relationships.

FCER1A

Top relations

related to Therapeutic relevance · 22
FCER1A → After, Although, As, Because FCER1A, CD23, FcεRI, IgE, IgE-FcεRI, IgE-mediated, In, Later, Ligelizumab, Many, MEDI4212, Omalizumab, Past, Quilizumab, The IgE-FcεRI, There, This
Bgee · 19
FCER1A → blood, bone marrow, carotid body, esophagus, gallbladder, granulocyte, lip, monocyte, mononuclear cell, muscle of thigh, oral cavity, skin of arm, skin of external ear, skin of hip, skin of thigh, spermatid, testicle, tunica adventitia of aorta, vulva
RNA expression pattern · 19
FCER1A → blood, bone marrow, carotid body, esophagus, gallbladder, granulocyte, lip, monocyte, mononuclear cell, muscle of thigh, oral cavity, skin of arm, skin of external ear, skin of hip, skin of thigh, spermatid, testicle, tunica adventitia of aorta, vulva
related to Gene regulation · 11
FCER1A → Elf-1, FCεRI, GATA-1, IgE, IL-4, In, Many, PU, The, These, YY1
Gene ontology · 7
FCER1A → cell surface, Fc-epsilon receptor signaling pathway, IgE binding, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane
related to history · 7
FCER1A → Early, FCER1A's, FcεRI, IgE, Later, One, Recent
related to Function · 6
FCER1A → Activation, FcεRI, IgE, Langerhans, The, When
related to Clinical significance · 4
FCER1A → Because FCER1A, Different FCER1A, IgE, The
related to Genetic variation · 4
FCER1A → IgE, In FCER1A, Some, The
Band · 2
FCER1A → 1 H3|1 80.33 cM, 1q23.2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ige fcεri receptor cells allergic gene mast expression binding promoter omalizumab studies also bp regulation human immune polymorphisms basophils signaling

FCER1A relationships Subject–Predicate–Object triples

TTTA extracted 122 structured relationships around FCER1A. Examples in this analysis include FCER1A → Aliases → FCER1A, FCE1A, FcERI, Fc fragment of IgE receptor Ia and FCER1A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2Q, 1F6A, 1J86, 1J87, 1J88, 1J89, 1RPQ, 2Y7Q. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FCER1AAliasesFCER1A, FCE1A, FcERI, Fc fragment of IgE receptor Ia1.00infobox
FCER1AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F2Q, 1F6A, 1J86, 1J87, 1J88, 1J89, 1RPQ, 2Y7Q1.00infobox
FCER1ABand1q23.21.00infobox
FCER1ABand1 H3|1 80.33 cM1.00infobox
FCER1ABgeeskin of thigh1.00infobox
FCER1ABgeeskin of hip1.00infobox
FCER1ABgeeskin of arm1.00infobox
FCER1ABgeegranulocyte1.00infobox
FCER1ABgeemononuclear cell1.00infobox
FCER1ABgeemonocyte1.00infobox
FCER1ABgeeoral cavity1.00infobox
FCER1ABgeevulva1.00infobox
FCER1ABgeetesticle1.00infobox
FCER1ABgeegallbladder1.00infobox
FCER1ABgeetunica adventitia of aorta1.00infobox
FCER1ABgeeblood1.00infobox
FCER1ABgeelip1.00infobox
FCER1ABgeebone marrow1.00infobox
FCER1ABgeeskin of external ear1.00infobox
FCER1ABgeeesophagus1.00infobox
FCER1ABgeemuscle of thigh1.00infobox
FCER1ABgeespermatid1.00infobox
FCER1ABgeecarotid body1.00infobox
FCER1ABioGPSMore reference expression data1.00infobox
FCER1AChr.Chromosome 1 (human)1.00infobox
FCER1AChr.Chromosome 1 (mouse)1.00infobox
FCER1ADatabasesNCBI: entry; OMA: entry1.00infobox
FCER1AEnd159,308,224 bp1.00infobox
FCER1AEnd173,054,781 bp1.00infobox
FCER1AEnsemblENSG000001796391.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around FCER1A bring nearby vocabulary together. In this analysis, examples include Associated, Levels and Ige. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • FCER1A
    • Associated
    • Levels
    • Ige
    • Polymorphisms
    • Gene
    • Expression
    • Genetic
    • Serum
    • May
    • Receptor
    • Regions
    • Promoter
  • fcer1a
    • Associated
    • Levels
    • Ige
    • Polymorphisms
    • Gene
    • Expression
    • Genetic
    • Serum
    • May
    • Receptor
    • Regions
    • Promoter
  • gene regulation
    • Chromosome
    • Bp
    • Chr
    • Human
    • Regions
    • Expression
    • Immune
    • Band
    • Genetic
    • Receptor
    • Associated
    • Polymorphisms
  • expression
    • Fcer1a
    • Regions
    • Gene
    • Regulation
    • Chromosome
    • Bp
    • Cell
    • Chr
    • Genetic
    • Human
    • Expressed
    • Promoter
  • gene
    • Chromosome
    • Bp
    • Chr
    • Human
    • Regions
    • Expression
    • Band
    • Genetic
    • Receptor
    • Regulation
    • Ige
    • Cell
  • genetic variation
    • Regulation
    • Chromosome
    • Bp
    • Chr
    • Human
    • Serum
    • Associated
    • Polymorphisms
    • Regions
    • Levels
    • Expression
    • Asthma
  • mast cells
    • Mast
    • Basophils
    • Immune
    • Monocytes
    • Expressed
    • Fcεri
    • Receptor
    • High
    • Regulation
    • Expression
    • Ige
    • Human
  • antigen presenting cells
    • Mast
    • Basophils
    • Immune
    • Monocytes
    • Expressed
    • Fcεri
    • Receptor
    • High
    • Regulation
    • Expression
    • Ige
    • Human

Connections between topic areas Semantic bridges

For FCER1A, one of the stronger structural bridges in this analysis connects FCER1A with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FCER1AFunction · splits 35 ⟂ 15
FCER1AGene regulation · splits 43 ⟂ 7
FCER1AExpression · splits 43 ⟂ 7
FCER1ATherapeutic relevance · splits 43 ⟂ 7
FCER1AStructure · splits 45 ⟂ 5
FCER1AOverview · splits 47 ⟂ 3
FCER1AClinical significance · splits 47 ⟂ 3

Map overview Semantic statistics

FCER1A

Nodes50
Edges49
Triples122
Avg. degree1.96
Density0.04
Components1

Source & methodology

TTTA analyzes the structure around FCER1A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Gene regulation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FCER1A · EN edition · Analysis: TopicsToTalkAbout

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