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CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic…
The analysis highlights Standards, Clinical significance and Overview as prominent areas in the source structure around CD23.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CD23 shows recurring relationship patterns in the source. For example, CD23 → carbohydrate binding, cytokine-mediated signaling pathway, external side of plasma membrane, extracellular exosome, extracellular region, IgE binding, integral component of membrane, integral component of plasma membrane, integrin binding, membrane, metal ion binding, Notch signaling pathway, plasma membrane, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of killing of cells of other organism, positive regulation of nitric-oxide synthase activity, positive regulation of nitric-oxide synthase biosynthetic process, protein binding Another extracted example is CD23 → appendix, blood, bone marrow cell, embryo, granulocyte, lymph node, mesenteric lymph nodes, monocyte, morula, mucosa of transverse colon, spleen, subcutaneous adipose tissue, testicle, thymus, tibiofemoral joint, tonsil, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cells ige human bp chr band antibody chromosome 19 receptor fc epsilon gene location cd23a known follicular fcer2 also external
TTTA extracted 100 structured relationships around CD23. Examples in this analysis include CD23 → Aliases → FCER2, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF, Fc fragment of IgE receptor II, FCErII, Fc epsilon receptor II and CD23 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KI1, 1T8C, 1T8D, 2H2R, 2H2T, 4EZM, 4G96, 4G9A, 4GI0, 4GJ0, 4GJX, 4GK1, 4GKO, 4J6J, 4J6K, 4J6L, 4J6M, 4J6N,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD23 | Aliases | FCER2, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF, Fc fragment of IgE receptor II, FCErII, Fc epsilon receptor II | 1.00 | infobox |
| CD23 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KI1, 1T8C, 1T8D, 2H2R, 2H2T, 4EZM, 4G96, 4G9A, 4GI0, 4GJ0, 4GJX, 4GK1, 4GKO, 4J6J, 4J6K, 4J6L, 4J6M, 4J6N,… | 1.00 | infobox |
| CD23 | Band | 19p13.2 | 1.00 | infobox |
| CD23 | Band | 8 A1.1|8 1.92 cM | 1.00 | infobox |
| CD23 | Bgee | testicle | 1.00 | infobox |
| CD23 | Bgee | granulocyte | 1.00 | infobox |
| CD23 | Bgee | spleen | 1.00 | infobox |
| CD23 | Bgee | lymph node | 1.00 | infobox |
| CD23 | Bgee | appendix | 1.00 | infobox |
| CD23 | Bgee | blood | 1.00 | infobox |
| CD23 | Bgee | monocyte | 1.00 | infobox |
| CD23 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| CD23 | Bgee | bone marrow cell | 1.00 | infobox |
| CD23 | Bgee | tonsil | 1.00 | infobox |
| CD23 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| CD23 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| CD23 | Bgee | embryo | 1.00 | infobox |
| CD23 | Bgee | thymus | 1.00 | infobox |
| CD23 | Bgee | tibiofemoral joint | 1.00 | infobox |
| CD23 | Bgee | white adipose tissue | 1.00 | infobox |
| CD23 | Bgee | morula | 1.00 | infobox |
| CD23 | BioGPS | More reference expression data | 1.00 | infobox |
| CD23 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| CD23 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| CD23 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD23 | End | 7,702,146 bp | 1.00 | infobox |
| CD23 | End | 3,744,175 bp | 1.00 | infobox |
| CD23 | Ensembl | ENSG00000104921 | 1.00 | infobox |
| CD23 | Entrez | 2208 | 1.00 | infobox |
| CD23 | External IDs | OMIM: 151445; MGI: 95497; GeneCards: FCER2 | 1.00 | infobox |
The concept neighborhoods around CD23 bring nearby vocabulary together. In this analysis, examples include Cells, Ige and Known. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CD23, one of the stronger structural bridges in this analysis connects CD23 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CD23 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CD23 · EN edition · Analysis: TopicsToTalkAbout