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Farnesyltransferase: Research & Standards

Farnesyltransferase (EC 2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small…

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Farnesyltransferase topic overview

The analysis highlights Research and Standards as prominent areas in the source structure around Farnesyltransferase.

Related topics
41
Source areas
3
Connected nodes
44
Extracted relationships
31
Concept neighborhoods
24
Bridge connections
44

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 29 topics
Farnesyltransferase structure and function · 10 topics
Structural studies · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA
enzyme data
CAS no.
131384-38-8
EC no.
2.5.1.58
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Farnesyltransferase structure and function

Structural studies

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Farnesyltransferase connects Entity context

The extracted context around Farnesyltransferase shows recurring relationship patterns in the source. For example, Farnesyltransferase → CaaX, Cysteine, FTase, FTase's, It, Only, The, There Another extracted example is Farnesyltransferase → All, Both, CaaX, SN2, The, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Farnesyltransferase

Top relations

related to Specificity · 8
Farnesyltransferase → CaaX, Cysteine, FTase, FTase's, It, Only, The, There
related to Farnesyltransferase structure and function · 6
Farnesyltransferase → All, Both, CaaX, SN2, The, This
related to overview · 3
Farnesyltransferase → Most, SH, This
BRENDA · 1
Farnesyltransferase → enzyme data
CAS no. · 1
Farnesyltransferase → 131384-38-8
EC no. · 1
Farnesyltransferase → 2.5.1.58
ExPASy · 1
Farnesyltransferase → NiceZyme view
Gene Ontology · 1
Farnesyltransferase → AmiGO / QuickGO
KEGG · 1
Farnesyltransferase → enzyme entry
MetaCyc · 1
Farnesyltransferase → metabolic pathway

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

proteins ftase farnesyl group substrates cysteine subunit protein also motif diphosphate alpha amino called caax acid inhibitors agents 58 enzyme

Farnesyltransferase relationships Subject–Predicate–Object triples

TTTA extracted 31 structured relationships around Farnesyltransferase. Examples in this analysis include Farnesyltransferase → BRENDA → enzyme data and Farnesyltransferase → CAS no. → 131384-38-8. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FarnesyltransferaseBRENDAenzyme data1.00infobox
FarnesyltransferaseCAS no.131384-38-81.00infobox
FarnesyltransferaseEC no.2.5.1.581.00infobox
FarnesyltransferaseExPASyNiceZyme view1.00infobox
FarnesyltransferaseGene OntologyAmiGO / QuickGO1.00infobox
FarnesyltransferaseKEGGenzyme entry1.00infobox
FarnesyltransferaseMetaCycmetabolic pathway1.00infobox
FarnesyltransferaseNCBIproteins1.00infobox
FarnesyltransferasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
FarnesyltransferasePMCarticles1.00infobox
FarnesyltransferasePubMedarticles1.00infobox
FarnesyltransferaseRheareactions1.00infobox
FarnesyltransferaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Farnesyltransferase bring nearby vocabulary together. In this analysis, examples include Substrates, Farnesyl and Group. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Farnesyltransferase
    • Substrates
    • Farnesyl
    • Group
    • Enzyme
    • Isoprenoid
    • Lipid
    • Two
    • Also
    • Called
    • Diphosphate
    • Protein
    • Cysteine
  • farnesyltransferase
    • Substrates
    • Farnesyl
    • Group
    • Enzyme
    • Isoprenoid
    • Lipid
    • Two
    • Also
    • Called
    • Diphosphate
    • Protein
    • Cysteine
  • farnesyltransferase structure and function
    • Substrates
    • Farnesyl
    • Group
    • Enzyme
    • Isoprenoid
    • Lipid
    • Proteins
    • Two
    • Also
    • Called
    • Diphosphate
    • Protein
  • farnesyl group
    • Called
    • Diphosphate
    • Isoprenoid
    • Proteins
    • Farnesyl
    • Group
    • Enzyme
    • Hydrophobic
    • Lipid
    • Farnesyltransferase
    • Protein
    • Type
  • farnesyl diphosphate
    • Diphosphate
    • Farnesyl
    • Group
    • Proteins
    • Enzyme
    • Hydrophobic
    • Isoprenoid
    • Lipid
    • Farnesyltransferase
    • Protein
    • Type
    • Cysteine
  • amino acid
    • Acids
    • Caax
    • Motif
    • Amino
    • Isoprenoid
    • Targets
    • Called
    • Protein
    • Three
    • Cysteine
    • Group
    • Ftase
  • cysteine
    • Farnesyl
    • Enzyme
    • Isoprenoid
    • Lipid
    • Pdb
    • Structures
    • Diphosphate
    • Motif
    • Type
    • Amino
    • Farnesyltransferase
    • Group
  • ftase inhibitors
    • Agents
    • Inhibitors
    • Protein
    • Shown
    • Anti-cancer
    • Isoprenoid
    • Acids
    • Also
    • Motif
    • Amino
    • Group
    • Proteins

Connections between topic areas Semantic bridges

For Farnesyltransferase, one of the stronger structural bridges in this analysis connects Farnesyltransferase with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Farnesyltransferase — Overview · splits 15 ⟂ 30
Farnesyltransferase — Farnesyltransferase structure and function · splits 34 ⟂ 11
Farnesyltransferase — Structural studies · splits 42 ⟂ 3

Map overview Semantic statistics

Farnesyltransferase

Nodes45
Edges44
Triples31
Avg. degree1.96
Density0.044444
Components1

Source & methodology

TTTA analyzes the structure around Farnesyltransferase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Farnesyltransferase · EN edition · Analysis: TopicsToTalkAbout

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