Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Exemestane

Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive…

Community, Culture, Applications & Research

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Exemestane. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L02BG06 (WHO)
Bioavailability
~60%[citation needed]
CAS Number
107868-30-4 Y
ChEBI
CHEBI:4953 N

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Exemestane

Nodes70
Edges69
Triples84
Avg. degree1.97
Density0.028571
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Exemestane

Top relations

related to Interactions · 9
Exemestane → AUC, Cmax, CYP3A4, Estrogens, It, Other, St John's Wort, The, While
related to Performance enhancement · 7
Exemestane → Along, FSH, It, LH, Selective, The, World Anti-Doping Agency's
related to Chemistry · 5
Exemestane → DMSO, It, Like, Optical, Pure
related to Pharmacokinetics · 5
Exemestane → CYP3A4, Highest, Maximal, Of, The
related to Research · 5
Exemestane → III, Interim, Oral, Preliminary, TEAM
has effect · 4
Exemestane → An, Aromasin, Nausea, The
related to Pharmacodynamics · 4
Exemestane → Any, ER-positive, Estrogen, The
is a · 3
Exemestane → irreversible steroidal aromatase inactivator of type I, steroid that is structurally similar to 4-androstenedione, white to off-white powder that is soluble in DMSO to at least 20 mg/mL
Legal status · 2
Exemestane → UK: POM (Prescription only), US: ℞-only
related to Medical uses · 2
Exemestane → October, US FDA

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

estrogen aromatase breast women cancer also postmenopausal tamoxifen enzyme inhibitors therapy cancers cyp3a4 inhibitor aromasin adjuvant premenopausal treatment patients mg

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Exemestane3D model (JSmol)Interactive image1.00infobox
ExemestaneAHFS/Drugs.comMonograph1.00infobox
ExemestaneATC codeL02BG06 (WHO)1.00infobox
ExemestaneBioavailability~60%[citation needed]1.00infobox
ExemestaneCAS Number107868-30-4 Y1.00infobox
ExemestaneChEBICHEBI:4953 N1.00infobox
ExemestaneChEMBLChEMBL1200374 Y1.00infobox
ExemestaneChemSpider54278 Y1.00infobox
ExemestaneCompTox Dashboard (EPA)DTXSID50230371.00infobox
ExemestaneDrug classAromatase inhibitor; Antiestrogen1.00infobox
ExemestaneDrugBankDB00990 Y1.00infobox
ExemestaneDuration of action4–5 days[citation needed]1.00infobox
ExemestaneECHA InfoCard100.171.1491.00infobox
ExemestaneElimination half-life24 hours1.00infobox
ExemestaneExcretionUrine and feces ~ 1:1 (mainly metabolites)1.00infobox
ExemestaneFormulaC20H24O21.00infobox
ExemestaneIUPHAR/BPS70731.00infobox
ExemestaneKEGGD00963 Y1.00infobox
ExemestaneLegal statusUK: POM (Prescription only)1.00infobox
ExemestaneLegal statusUS: ℞-only1.00infobox
ExemestaneMedlinePlusa6070061.00infobox
ExemestaneMetabolismLiver (CYP3A4, aldo-keto reductase)1.00infobox
ExemestaneMolar mass296.410 g·mol−11.00infobox
ExemestaneOther namesFCE-243041.00infobox
ExemestanePronunciation/ˌɛksəˈmɛˌsteɪn/ EK-sə-ME-stayn1.00infobox
ExemestaneProtein binding90%1.00infobox
ExemestanePubChem CID601981.00infobox
ExemestaneRoutes of administrationBy mouth1.00infobox
ExemestaneTrade namesAromasin1.00infobox
ExemestaneUNIINY22HMQ4BX1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.