Riluzole

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Riluzole topic overview

The analysis highlights Applications and Research as prominent areas in the source structure around Riluzole.

Related topics: 47
Source areas: 7
Connected nodes: 54
Extracted relationships: 57
Concept neighborhoods: 21
Bridge connections: 54

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Research · 20 topics

Adverse effects · 9 topics

Mechanism of action · 7 topics

Overview · 5 topics

Medical uses · 3 topics

Synthesis · 2 topics

Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol): Interactive image
AHFS/Drugs.com: Monograph
ATC code: N07XX02 (WHO)
Bioavailability: 60±18%
CAS Number: 1744-22-5 Y
ChEMBL: ChEMBL744 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Food and Drug Administration
European Medicines Agency (EMA) European Medicines Agency
Cochrane Library

Adverse effects

Interactions

CYP1A2

Mechanism of action

TTX Tetrodotoxin
Sodium channels Sodium channel
Neurons Neuron
Kainate Kainate receptor
NMDA receptors NMDA receptor
GABAA receptors GABAA receptor
Glutamate receptors Glutamate receptor

Synthesis

Research

Case studies Case study
Randomized controlled trials Randomized controlled trial
Neuroprotective Neuroprotection
Glutamate Glutamate (neurotransmitter)
Mood disorders Mood disorder
Anxiety disorders Anxiety disorder
Huntington's disease
Parkinson's disease
American Spinal Injury Association
Mortality rates Mortality rate
Noise-induced hearing loss
Cisplatin
Ototoxicity Ototoxic
Antioxidant
Apoptotic
Sublingual
Yale University
Generalized anxiety disorder
Prodrug
Troriluzole

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Riluzole connects Entity context

The extracted context around Riluzole shows recurring relationship patterns in the source. For example, Riluzole → ALS, Cochrane Library, Drug Administration, EMA, European Medicines Agency, FDA, In, United States, US Food Another extracted example is Riluzole → GABAA, However, In, NMDA, Rather, The, TTX-sensitive. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Amyotrophic lateral sclerosis · 9

Riluzole → ALS, Cochrane Library, Drug Administration, EMA, European Medicines Agency, FDA, In, United States, US Food

related to Mechanism of action · 7

Riluzole → GABAA, However, In, NMDA, Rather, The, TTX-sensitive

related to Research · 7

Riluzole → American Spinal Injury Association, ASIA, However, Huntington's, NIHL, Parkinson's, These

Legal status · 5

Riluzole → AU: S4 (Prescription only), CA: ℞-only, EU: Rx Only, UK: POM (Prescription only), US: ℞-only

related to Legal status · 2

Riluzole → European Union, October

3D model (JSmol) · 1

Riluzole → Interactive image

AHFS/Drugs.com · 1

Riluzole → Monograph

ATC code · 1

Riluzole → N07XX02 (WHO)

Bioavailability · 1

Riluzole → 60±18%

CAS Number · 1

Riluzole → 1744-22-5 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

glutamate also may known effects treatment disease als states available action amyotrophic lateral sclerosis binding exservan legal status cyp1a2 approved

Riluzole relationships Subject–Predicate–Object triples

TTTA extracted 57 structured relationships around Riluzole. Examples in this analysis include Riluzole → 3D model (JSmol) → Interactive image and Riluzole → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Riluzole	3D model (JSmol)	Interactive image	1.00	infobox
Riluzole	AHFS/Drugs.com	Monograph	1.00	infobox
Riluzole	ATC code	N07XX02 (WHO)	1.00	infobox
Riluzole	Bioavailability	60±18%	1.00	infobox
Riluzole	CAS Number	1744-22-5 Y	1.00	infobox
Riluzole	ChEMBL	ChEMBL744 Y	1.00	infobox
Riluzole	ChemSpider	4892 Y	1.00	infobox
Riluzole	CompTox Dashboard (EPA)	DTXSID3045192	1.00	infobox
Riluzole	DrugBank	DB00740 Y	1.00	infobox
Riluzole	ECHA InfoCard	100.124.754	1.00	infobox
Riluzole	Elimination half-life	9–15 hours	1.00	infobox
Riluzole	Excretion	Urine (90%)	1.00	infobox
Riluzole	Formula	C8H5F3N2OS	1.00	infobox
Riluzole	IUPHAR/BPS	2326	1.00	infobox
Riluzole	KEGG	D00775 Y	1.00	infobox
Riluzole	Legal status	AU: S4 (Prescription only)	1.00	infobox
Riluzole	Legal status	CA: ℞-only	1.00	infobox
Riluzole	Legal status	UK: POM (Prescription only)	1.00	infobox
Riluzole	Legal status	US: ℞-only	1.00	infobox
Riluzole	Legal status	EU: Rx Only	1.00	infobox
Riluzole	MedlinePlus	a696013	1.00	infobox
Riluzole	Metabolism	Hepatic (CYP1A2)	1.00	infobox
Riluzole	Molar mass	234.20 g·mol−1	1.00	infobox
Riluzole	Pregnancy category	AU: B3	1.00	infobox
Riluzole	Protein binding	97%	1.00	infobox
Riluzole	PubChem CID	5070	1.00	infobox
Riluzole	Routes of administration	By mouth	1.00	infobox
Riluzole	Trade names	Rilutek, Tiglutik, Exservan, others	1.00	infobox
Riluzole	UNII	7LJ087RS6F	1.00	infobox
Riluzole	is a	medication used to treat amyotrophic lateral sclerosis	0.90	text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Riluzole bring nearby vocabulary together. In this analysis, examples include Known, Glutamate and Als. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Riluzole
- Known
- Glutamate
- Als
- Approved
- Use
- May
- Treatment
- Also
- Available
- Contraindications
- Cyp1a2
- Exservan
riluzole
- Known
- Glutamate
- Als
- Approved
- Use
- May
- Treatment
- Also
- Available
- Contraindications
- Cyp1a2
- Exservan
amyotrophic lateral sclerosis
- Lateral
- Sclerosis
- Als
- Administration
- Legal
- Status
- Contraindications
- Cyp1a2
- Drugs
- Exservan
- Medical
- Motor
food and drug administration
- Legal
- Status
- Amyotrophic
- Contraindications
- Cyp1a2
- Drugs
- Exservan
- Lateral
- Medical
- Overdose
- Pregnancy
- Receptors
adverse effects
- Administration
- Also
- Glutamate
- Legal
- Status
- Cyp1a2
- Drugs
- Exservan
- Lateral
- Medical
- Months
- Motor
mechanism of action
- Binding
- Drug
- Administration
- Legal
- Status
- Also
- Amyotrophic
- Contraindications
- Cyp1a2
- Drugs
- Exservan
- Lateral
medical uses
- Approved
- Administration
- Legal
- Status
- Contraindications
- Cyp1a2
- Drugs
- Overdose
- Pregnancy
- Research
- Sclerosis
- United
cyp1a2
- Legal
- Status
- Drugs
- Exservan
- Lateral
- Medical
- Overdose
- Pregnancy
- Research
- Sclerosis
- United
- Approved

Connections between topic areas Semantic bridges

For Riluzole, one of the stronger structural bridges in this analysis connects Riluzole with Research. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Riluzole — Research · splits 34 ⟂ 21

Riluzole — Adverse effects · splits 45 ⟂ 10

Riluzole — Mechanism of action · splits 47 ⟂ 8

Riluzole — Overview · splits 49 ⟂ 6

Riluzole — Medical uses · splits 51 ⟂ 4

Riluzole — Synthesis · splits 52 ⟂ 3

Map overview Semantic statistics

Riluzole

Nodes55

Edges54

Triples57

Avg. degree1.96

Density0.036364

Components1

Source & methodology

TTTA analyzes the structure around Riluzole to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Riluzole · EN edition · Analysis: TopicsToTalkAbout