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Riluzole

Riluzole is a medication used to treat amyotrophic lateral sclerosis (ALS) and other motor neuron diseases. Riluzole delays the onset of ventilator-dependence or tracheostomy in some people and may increase survival by two to three months. Riluzole is available in tablet and liquid form. A thin film version of riluzole which dissolves on the tongue…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N07XX02 (WHO)
Bioavailability
60±18%
CAS Number
1744-22-5 Y
ChEMBL
ChEMBL744 Y

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Overview

Medical uses

Adverse effects

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Mechanism of action

Synthesis

Research

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Map overview Semantic statistics

Riluzole

Nodes55
Edges54
Triples57
Avg. degree1.96
Density0.036364
Components1

How this topic connects Entity context

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Riluzole

Top relations

related to Amyotrophic lateral sclerosis · 9
Riluzole → ALS, Cochrane Library, Drug Administration, EMA, European Medicines Agency, FDA, In, United States, US Food
related to Mechanism of action · 7
Riluzole → GABAA, However, In, NMDA, Rather, The, TTX-sensitive
related to Research · 7
Riluzole → American Spinal Injury Association, ASIA, However, Huntington's, NIHL, Parkinson's, These
Legal status · 5
Riluzole → AU: S4 (Prescription only), CA: ℞-only, EU: Rx Only, UK: POM (Prescription only), US: ℞-only
related to Legal status · 2
Riluzole → European Union, October
3D model (JSmol) · 1
Riluzole → Interactive image
AHFS/Drugs.com · 1
Riluzole → Monograph
ATC code · 1
Riluzole → N07XX02 (WHO)
Bioavailability · 1
Riluzole → 60±18%
CAS Number · 1
Riluzole → 1744-22-5 Y

Important terminology Word statistics

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Important terminology

glutamate also may known effects treatment disease als states available action amyotrophic lateral sclerosis binding exservan legal status cyp1a2 approved

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Riluzole3D model (JSmol)Interactive image1.00infobox
RiluzoleAHFS/Drugs.comMonograph1.00infobox
RiluzoleATC codeN07XX02 (WHO)1.00infobox
RiluzoleBioavailability60±18%1.00infobox
RiluzoleCAS Number1744-22-5 Y1.00infobox
RiluzoleChEMBLChEMBL744 Y1.00infobox
RiluzoleChemSpider4892 Y1.00infobox
RiluzoleCompTox Dashboard (EPA)DTXSID30451921.00infobox
RiluzoleDrugBankDB00740 Y1.00infobox
RiluzoleECHA InfoCard100.124.7541.00infobox
RiluzoleElimination half-life9–15 hours1.00infobox
RiluzoleExcretionUrine (90%)1.00infobox
RiluzoleFormulaC8H5F3N2OS1.00infobox
RiluzoleIUPHAR/BPS23261.00infobox
RiluzoleKEGGD00775 Y1.00infobox
RiluzoleLegal statusAU: S4 (Prescription only)1.00infobox
RiluzoleLegal statusCA: ℞-only1.00infobox
RiluzoleLegal statusUK: POM (Prescription only)1.00infobox
RiluzoleLegal statusUS: ℞-only1.00infobox
RiluzoleLegal statusEU: Rx Only1.00infobox
RiluzoleMedlinePlusa6960131.00infobox
RiluzoleMetabolismHepatic (CYP1A2)1.00infobox
RiluzoleMolar mass234.20 g·mol−11.00infobox
RiluzolePregnancy categoryAU: B31.00infobox
RiluzoleProtein binding97%1.00infobox
RiluzolePubChem CID50701.00infobox
RiluzoleRoutes of administrationBy mouth1.00infobox
RiluzoleTrade namesRilutek, Tiglutik, Exservan, others1.00infobox
RiluzoleUNII7LJ087RS6F1.00infobox
Riluzoleis amedication used to treat amyotrophic lateral sclerosis0.90text

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