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Droxidopa

Droxidopa, also known as L-threo-dihydroxyphenylserine (L-DOPS) and sold under the brand names Northera and Dops among others, is sympathomimetic medication which is used in the treatment of hypotension (low blood pressure) and for other indications. It is taken by mouth.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C01CA27 (WHO)
Bioavailability
90%
CAS Number
23651-95-8 Y
ChEBI
CHEBI:31524

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Overview

Medical uses

Side effects

Pharmacology

Chemistry

History

Society and culture

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Map overview Semantic statistics

Droxidopa

Nodes88
Edges87
Triples92
Avg. degree1.98
Density0.022727
Components1

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Droxidopa

Top relations

related to Pharmacology · 13
Droxidopa → AAAD, AAADI, BBB, CNS, DDC, DOPA, Increased, It, L-amino, Lodosyn, NOH, Patients, PNS
related to Clinical trials · 11
Droxidopa → Chelsea Therapeutics, In, Lundbeck, Midodrine, MSA, NOH, ODS, PAF, PD, Sept, US
related to history · 9
Droxidopa → Asian, FAP, IDH, Japan, MSA, NOH, PD, Sumitomo Pharmaceuticals, The
related to Medical uses · 8
Droxidopa → FAP, For, IDH, MSA, NOH, PAF, Parkinson's, The
related to Chemistry · 5
Droxidopa → L-3, L-DOPA, L-DOPS, L-serine, Whereas
related to External links · 5
Droxidopa → Archived, Drug Information Portal, January, Medicine, National Library
related to Names · 5
Droxidopa → Brand, Dops, INNTooltip International Nonproprietary Name, JANTooltip Japanese Accepted Name, Northera
Legal status · 2
Droxidopa → In general: ℞ (Prescription only), US: ℞-only
is a · 2
Droxidopa → precursor and prodrug of norepinephrine, synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine
has effect · 2
Droxidopa → The, With

Important terminology Word statistics

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Important terminology

norepinephrine treatment hypotension also blood orthostatic indications names drug used side effects acid noh dizziness prodrug levodopa brain japan l-dops

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Droxidopa3D model (JSmol)Interactive image1.00infobox
DroxidopaAHFS/Drugs.comMonograph1.00infobox
DroxidopaATC codeC01CA27 (WHO)1.00infobox
DroxidopaBioavailability90%1.00infobox
DroxidopaCAS Number23651-95-8 Y1.00infobox
DroxidopaChEBICHEBI:315241.00infobox
DroxidopaChEMBLChEMBL21038271.00infobox
DroxidopaChemSpider839271.00infobox
DroxidopaCompTox Dashboard (EPA)DTXSID60464221.00infobox
DroxidopaDrugBankDB062621.00infobox
DroxidopaECHA InfoCard100.215.2541.00infobox
DroxidopaElimination half-life1.5 hours1.00infobox
DroxidopaExcretionKidney1.00infobox
DroxidopaFormulaC9H11NO51.00infobox
DroxidopaKEGGD012771.00infobox
DroxidopaLegal statusUS: ℞-only1.00infobox
DroxidopaLegal statusIn general: ℞ (Prescription only)1.00infobox
DroxidopaLicense dataUS DailyMed: Droxidopa1.00infobox
DroxidopaMedlinePlusa6140251.00infobox
DroxidopaMetabolismLiver1.00infobox
DroxidopaMetabolitesNorepinephrine1.00infobox
DroxidopaMolar mass213.189 g·mol−11.00infobox
DroxidopaOther names3,4-Dihydroxyphenylserine; 3,4-threo-DOPS; L-threo-Dihydroxyphenylserine; L-DOPS; L-threo-DOPS; Threo-DOPS; β,3-Dihydroxytyrosine; (–)-threo-3-(3,4-Dihydroxyphenyl)-L-serine; SM…1.00infobox
DroxidopaPubChem CID929741.00infobox
DroxidopaRoutes of administrationBy mouth1.00infobox
DroxidopaTrade namesNorthera, Dops1.00infobox
DroxidopaUNIIJ7A92W69L71.00infobox
Droxidopais asynthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine0.90text
Droxidopais aprecursor and prodrug of norepinephrine0.90text

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