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Midodrine

Midodrine, sold under the brand name Proamatine among others, is an antihypotensive medication used to treat orthostatic hypotension (low blood pressure when standing) and urinary incontinence. It is taken by mouth.

[EN, English, English]

History, Community, Culture & Applications

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Explore the main themes, entities and connections around Midodrine. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C01CA17 (WHO)
Bioavailability
93% (as desglymidodrine)
CAS Number
42794-76-3 Y
ChEBI
CHEBI:6933

Topics to explore

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Overview

Medical uses

Contraindications

Pharmacology

Chemistry

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Midodrine

Nodes72
Edges71
Triples65
Avg. degree1.97
Density0.027778
Components1

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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Midodrine

Top relations

related to Names · 11
Midodrine → Amatine, British Approved Name, Gutron, In, Japanese Accepted Name, Midamine, Midon, Proamatine, ST-1085, TS-701, United States Adopted Name
related to history · 9
Midodrine → Drug Administration, FDA, Food, In August, In September, It, September, Shire, United States
related to External links · 3
Midodrine → Media, Wikimedia Commons, Wiktionary-logo-en-v2
related to Medical uses · 3
Midodrine → It, Small, Studies
Legal status · 2
Midodrine → AU: S4 (Prescription only), US: ℞-only
is a · 2
Midodrine → odorless, prodrug of its active metabolite desglymidodrine
related to Pharmacokinetics · 2
Midodrine → After, The
related to Synthesis · 2
Midodrine → Acylation, The
3D model (JSmol) · 1
Midodrine → Interactive image
AHFS/Drugs.com · 1
Midodrine → Monograph

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

blood pressure desglymidodrine metabolite used orthostatic urinary also drug name others agonist names prodrug available effects medical proamatine mouth α1-adrenergic

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Midodrine3D model (JSmol)Interactive image1.00infobox
MidodrineAHFS/Drugs.comMonograph1.00infobox
MidodrineATC codeC01CA17 (WHO)1.00infobox
MidodrineBioavailability93% (as desglymidodrine)1.00infobox
MidodrineCAS Number42794-76-3 Y1.00infobox
MidodrineChEBICHEBI:69331.00infobox
MidodrineChEMBLChEMBL12012121.00infobox
MidodrineChemSpider40501.00infobox
MidodrineChiralityRacemic mixture1.00infobox
MidodrineCompTox Dashboard (EPA)DTXSID00233211.00infobox
MidodrineDrug classα1-Adrenergic receptor agonist; Antihypotensive agent1.00infobox
MidodrineDrugBankDB002111.00infobox
MidodrineDuration of action2–6 hours1.00infobox
MidodrineECHA InfoCard100.151.349 100.050.842, 100.151.3491.00infobox
MidodrineElimination half-lifeMidodrine: 0.5 hours Desglymidodrine: 2–4 hours1.00infobox
MidodrineFormulaC12H18N2O41.00infobox
MidodrineIUPHAR/BPS72401.00infobox
MidodrineKEGGD082201.00infobox
MidodrineLegal statusAU: S4 (Prescription only)1.00infobox
MidodrineLegal statusUS: ℞-only1.00infobox
MidodrineLicense dataUS DailyMed: Midodrine1.00infobox
MidodrineMedlinePlusa6160301.00infobox
MidodrineMetabolismDeglycination1.00infobox
MidodrineMetabolites• Desglymidodrine1.00infobox
MidodrineMolar mass254.286 g·mol−11.00infobox
MidodrineOnset of action≤1 hour1.00infobox
MidodrineOther namesST-1085; TS-701; 2,5-Dimethoxy-β-hydroxy-N-(aminoethanonyl)phenethylamine; 2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide; 1-2',5'-Dimethoxyphenyl-1)-2 glycinamidoe…1.00infobox
MidodrinePregnancy categoryAU: C1.00infobox
MidodrinePubChem CID41951.00infobox
MidodrineRoutes of administrationBy mouth1.00infobox

Related concept clusters Concept neighborhoods

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