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Digitoxin

Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting. Unlike digoxin, which is eliminated from the body via the kidneys, it is eliminated via the liver, and so can be used in patients…

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3D model (JSmol)
Interactive image
ATC code
C01AA04 (WHO)
Bioavailability
98–100% (oral)
CAS Number
71-63-6 Y
ChEBI
CHEBI:28544 N
ChEMBL
ChEMBL254219 N

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Overview

Medical uses

Contraindications

Adverse effects and toxicity

Interactions

Pharmacology

History

Use as a weapon

Research

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Map overview Semantic statistics

Digitoxin

Nodes77
Edges76
Triples68
Avg. degree1.97
Density0.025974
Components1

How this topic connects Entity context

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Digitoxin

Top relations

related to In fiction · 22
Digitoxin → Affair, Agatha Christie's Appointment, Calliphoridae, Casino Royale, College, Columbo, Country Roads, Crown, DeathElizabeth Peters' Die For, Heart, LoveCSI, Man, McMillan, Murder, Murder She Wrote, Private Practice, Rosewood, Several, The Descent, The Hardest Part
related to External links · 9
Digitoxin → Digoxin, Geriatric Population, Media, Medscape, Old Drug Be Rediscovered, Should, Toxicity, Wikimedia Commons Comparing, Wiktionary-logo-en-v2
related to Pharmacokinetics · 5
Digitoxin → CYP3A4, In, It, The, When
related to Interactions · 3
Digitoxin → CYP3A4, Drugs, P-gp
related to Use as a weapon · 2
Digitoxin → Belgian, Marie Alexandrine Becker
3D model (JSmol) · 1
Digitoxin → Interactive image
ATC code · 1
Digitoxin → C01AA04 (WHO)
Bioavailability · 1
Digitoxin → 98–100% (oral)
CAS Number · 1
Digitoxin → 71-63-6 Y
ChEBI · 1
Digitoxin → CHEBI:28544 N

Important terminology Word statistics

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Important terminology

digoxin heart used cyp3a4 toxicity via liver kidney failure use effects people include treatment certain function patients faeces structure impaired

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Digitoxin3D model (JSmol)Interactive image1.00infobox
DigitoxinATC codeC01AA04 (WHO)1.00infobox
DigitoxinBioavailability98–100% (oral)1.00infobox
DigitoxinCAS Number71-63-6 Y1.00infobox
DigitoxinChEBICHEBI:28544 N1.00infobox
DigitoxinChEMBLChEMBL254219 N1.00infobox
DigitoxinChemSpider389987 N1.00infobox
DigitoxinCompTox Dashboard (EPA)DTXSID00229331.00infobox
DigitoxinDrugBankDB01396 N1.00infobox
DigitoxinECHA InfoCard100.000.6911.00infobox
DigitoxinElimination half-life7–8 days1.00infobox
DigitoxinExcretion60% via urine, 40% via faeces1.00infobox
DigitoxinFormulaC41H64O131.00infobox
DigitoxinIUPHAR/BPS67821.00infobox
DigitoxinKEGGD00297 N1.00infobox
DigitoxinLegal statusIn general: ℞ (Prescription only)1.00infobox
DigitoxinMetabolismLiver (CYP3A4)1.00infobox
DigitoxinMolar mass764.950 g·mol−11.00infobox
DigitoxinProtein binding90–97%1.00infobox
DigitoxinPubChem CID4412071.00infobox
DigitoxinRoutes of administrationBy mouth, Intravenous injection1.00infobox
DigitoxinTrade namesDigalen, Digitaline, Digitmerck, others1.00infobox
DigitoxinUNIIE90NZP2L9U1.00infobox
Digitoxinis acardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia0.90text

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