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Digitoxin: History, Applications, Research & Art

Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting. Unlike digoxin, which is eliminated from the body via the kidneys, it is eliminated via the liver, and so can be used in patients…

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Digitoxin topic overview

The analysis highlights History, Applications, Research and Art as prominent areas in the source structure around Digitoxin.

Related topics
67
Source areas
9
Connected nodes
76
Extracted relationships
68
Concept neighborhoods
17
Bridge connections
76

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 17 topics
Pharmacology · 11 topics
Use as a weapon · 11 topics
Contraindications · 9 topics
Overview · 6 topics
Adverse effects and toxicity · 4 topics
History · 4 topics
Research · 3 topics
Medical uses · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
C01AA04 (WHO)
Bioavailability
98–100% (oral)
CAS Number
71-63-6 Y
ChEBI
CHEBI:28544 N
ChEMBL
ChEMBL254219 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects and toxicity

Interactions

Pharmacology

History

Use as a weapon

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Digitoxin connects Entity context

The extracted context around Digitoxin shows recurring relationship patterns in the source. For example, Digitoxin → Affair, Agatha Christie's Appointment, Calliphoridae, Casino Royale, College, Columbo, Country Roads, Crown, DeathElizabeth Peters' Die For, Heart, LoveCSI, Man, McMillan, Murder, Murder She Wrote, Private Practice, Rosewood, Several, The Descent, The Hardest Part Another extracted example is Digitoxin → Digoxin, Geriatric Population, Media, Medscape, Old Drug Be Rediscovered, Should, Toxicity, Wikimedia Commons Comparing, Wiktionary-logo-en-v2. Use these groups to spot repeated connection types before inspecting the individual relationships.

Digitoxin

Top relations

related to In fiction · 22
Digitoxin → Affair, Agatha Christie's Appointment, Calliphoridae, Casino Royale, College, Columbo, Country Roads, Crown, DeathElizabeth Peters' Die For, Heart, LoveCSI, Man, McMillan, Murder, Murder She Wrote, Private Practice, Rosewood, Several, The Descent, The Hardest Part
related to External links · 9
Digitoxin → Digoxin, Geriatric Population, Media, Medscape, Old Drug Be Rediscovered, Should, Toxicity, Wikimedia Commons Comparing, Wiktionary-logo-en-v2
related to Pharmacokinetics · 5
Digitoxin → CYP3A4, In, It, The, When
related to Interactions · 3
Digitoxin → CYP3A4, Drugs, P-gp
related to Use as a weapon · 2
Digitoxin → Belgian, Marie Alexandrine Becker
3D model (JSmol) · 1
Digitoxin → Interactive image
ATC code · 1
Digitoxin → C01AA04 (WHO)
Bioavailability · 1
Digitoxin → 98–100% (oral)
CAS Number · 1
Digitoxin → 71-63-6 Y
ChEBI · 1
Digitoxin → CHEBI:28544 N

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

digoxin heart used cyp3a4 toxicity via liver kidney failure use effects people include treatment certain function patients faeces structure impaired

Digitoxin relationships Subject–Predicate–Object triples

TTTA extracted 68 structured relationships around Digitoxin. Examples in this analysis include Digitoxin → 3D model (JSmol) → Interactive image and Digitoxin → ATC code → C01AA04 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Digitoxin3D model (JSmol)Interactive image1.00infobox
DigitoxinATC codeC01AA04 (WHO)1.00infobox
DigitoxinBioavailability98–100% (oral)1.00infobox
DigitoxinCAS Number71-63-6 Y1.00infobox
DigitoxinChEBICHEBI:28544 N1.00infobox
DigitoxinChEMBLChEMBL254219 N1.00infobox
DigitoxinChemSpider389987 N1.00infobox
DigitoxinCompTox Dashboard (EPA)DTXSID00229331.00infobox
DigitoxinDrugBankDB01396 N1.00infobox
DigitoxinECHA InfoCard100.000.6911.00infobox
DigitoxinElimination half-life7–8 days1.00infobox
DigitoxinExcretion60% via urine, 40% via faeces1.00infobox
DigitoxinFormulaC41H64O131.00infobox
DigitoxinIUPHAR/BPS67821.00infobox
DigitoxinKEGGD00297 N1.00infobox
DigitoxinLegal statusIn general: ℞ (Prescription only)1.00infobox
DigitoxinMetabolismLiver (CYP3A4)1.00infobox
DigitoxinMolar mass764.950 g·mol−11.00infobox
DigitoxinProtein binding90–97%1.00infobox
DigitoxinPubChem CID4412071.00infobox
DigitoxinRoutes of administrationBy mouth, Intravenous injection1.00infobox
DigitoxinTrade namesDigalen, Digitaline, Digitmerck, others1.00infobox
DigitoxinUNIIE90NZP2L9U1.00infobox
Digitoxinis acardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Digitoxin bring nearby vocabulary together. In this analysis, examples include Heart, Toxicity and Used. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Digitoxin
    • Heart
    • Toxicity
    • Used
    • Digoxin
    • Failure
    • Treatment
    • Cyp3a4
    • Diuretics
    • Effective
    • Mechanism
    • Metabolism
    • P-gp
  • digitoxin
    • Heart
    • Toxicity
    • Used
    • Digoxin
    • Failure
    • Treatment
    • Cyp3a4
    • Diuretics
    • Effective
    • Mechanism
    • Metabolism
    • P-gp
  • heart failure
    • Treatment
    • Used
    • Failure
    • Heart
    • Contraindications
    • Kinds
    • Several
    • Weapon
    • Effective
    • Heartbeat
    • Levels
    • Mechanism
  • heart arrhythmia
    • Kinds
    • Certain
    • Used
    • Failure
    • Cardiac
    • Contraindications
    • Heart
    • Several
    • Weapon
    • Heartbeat
    • Levels
    • Potassium
  • cyp3a4
    • Include
    • Diuretics
    • Metabolism
    • P-gp
    • Heartbeat
    • Levels
    • Potassium
    • Liver
    • Toxicity
    • Digitoxin
    • Heart
    • Bradycardia
  • contraindications
    • Bradycardia
    • Mechanism
    • Metabolism
    • Uses
    • Weapon
    • Heart
    • Effects
    • Faeces
    • Failure
    • Function
    • Heartbeat
    • Impaired
  • adverse effects and toxicity
    • Similar
    • Mechanism
    • Metabolism
    • Treatment
    • Cyp3a4
    • Contraindications
    • Structure
    • Uses
    • Weapon
    • Digoxin
    • Bradycardia
    • Diuretics
  • use as a weapon
    • People
    • Contraindications
    • Mechanism
    • Metabolism
    • Several
    • Used
    • Uses
    • Heart
    • Effects
    • Faeces
    • Failure
    • Function

Connections between topic areas Semantic bridges

For Digitoxin, one of the stronger structural bridges in this analysis connects Digitoxin with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DigitoxinInteractions · splits 59 ⟂ 18
DigitoxinPharmacology · splits 65 ⟂ 12
DigitoxinUse as a weapon · splits 65 ⟂ 12
DigitoxinContraindications · splits 67 ⟂ 10
DigitoxinOverview · splits 70 ⟂ 7
DigitoxinAdverse effects and toxicity · splits 72 ⟂ 5
DigitoxinHistory · splits 72 ⟂ 5
DigitoxinResearch · splits 73 ⟂ 4
DigitoxinMedical uses · splits 74 ⟂ 3

Map overview Semantic statistics

Digitoxin

Nodes77
Edges76
Triples68
Avg. degree1.97
Density0.025974
Components1

Source & methodology

TTTA analyzes the structure around Digitoxin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Research & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Digitoxin · EN edition · Analysis: TopicsToTalkAbout

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